HPA-1 polymorphism of αIIbβ3 modulates platelet adhesion onto immobilized fibrinogen in an in-vit... more HPA-1 polymorphism of αIIbβ3 modulates platelet adhesion onto immobilized fibrinogen in an in-vitro flow system
The incidence of acquired von Willebrand syndrome (AvWS) in patients with heart disease is common... more The incidence of acquired von Willebrand syndrome (AvWS) in patients with heart disease is commonly perceived as rare. However, its occurrence is underestimated and underdiagnosed, potentially leading to inadequate treatment resulting in increased morbidity and mortality.In patients with cardiac disease, AvWS frequently occurs in patients with structural heart disease and in those undergoing mechanical circulatory support (MCS).The clinical manifestation of an AvWS is usually characterized by apparent or occult gastrointestinal (GI) or mucocutaneous hemorrhage frequently accompanied by signs of anemia and/or increased bleeding during surgical procedures. The primary change is loss of high-molecular weight von Willebrand factor multimers (HMWM). Whereas the loss of HMWM in patients with structural heart disease is caused by increased HMWM cleavage by von Willebrand factor (vWF)-cleaving protease, ADAMTS13, AvWS in MCS patients is predominantly a result of a high shear stress coupled ...
It is known that shoulder surgery may cause iatrogenic injury to the axillary nerve as a serious ... more It is known that shoulder surgery may cause iatrogenic injury to the axillary nerve as a serious complication, but there is little evidence to indicate whether the axillary nerve is at risk of injury during an anterolateral acromial approach for minimally-invasive plate osteosynthesis (MIPO) of proximal humerus fractures. We hypothesised that this surgical method is safe for the axillary nerve and would preserve it from iatrogenic injury. We conducted a prospective follow-up cohort study on 49 consecutive patients with proximal humerus fractures who were managed with MIPO through an anterolateral approach. All patients underwent standardised electroneurographic testing, with assessment of amplitudes of evoked compound muscle action potentials (CMAP) and distal motor latencies (DML) of the axillary nerves, pre- and post-operatively. Six weeks after injury, all patients underwent needle electromyographic (EMG) testing of anterior, middle, posterior deltoid, teres minor and paraspinal ...
3. kongres Hrvatskog društva za neurovaskularne poremećaje Hrvatskog liječeničkog zbora i Hrvatskog društva za prevenciju moždanog udara sa međunarodnim sudjelovanjem _knjiga sažetaka ; u: Liječnički vjesnik 128 (2006) (S), 2006
Tenzijska glavobolja spada u skupinu primarnih glavobolja, nedovoljno poznatog uzroka. Rizik nast... more Tenzijska glavobolja spada u skupinu primarnih glavobolja, nedovoljno poznatog uzroka. Rizik nastanka ove primarne glavobolje nije jasno defi niran kao ni tijek bolesti. Internacionalno udruženje za glavobolju klasifi ciralo je glavobolje u primarne i sekundarne. Posebnu pažnju pridaje klasifi kaciji tenzijskih glavobolja, tzv. Tension-Type Headache (TTH). Prema toj klasifi kaciji TTH se s obzirom na učestalost pojavljivanja dijeli na epizodne tenzijske glavobolje, učestale-epizodične tenzijske glavobolje te kronične tenzijske glavobolje. Nadalje, epizodične TTH dijele se s obzirom na perikranijsku napetost. Epizodične tenzijske glavobolje mogu biti rijetke (do 12 dana/godišnje) i učestale epizodične TTH koje se češće javljaju i duže traju (<15 dana/mjesec). Kronične TTH traju 15 ili više dana/ mjesec (tablica 1). Kronična TTH značajno umanjuje kvalitetu života (QOL) oboljelog zbog intenziteta boli kao i trajanja bolnog sindroma. Uz to, diferencira se i moguća TTH kao epizodična ...
HPA-1 polymorphism of αIIbβ3 modulates platelet adhesion onto immobilized fibrinogen in an in-vit... more HPA-1 polymorphism of αIIbβ3 modulates platelet adhesion onto immobilized fibrinogen in an in-vitro flow system
The incidence of acquired von Willebrand syndrome (AvWS) in patients with heart disease is common... more The incidence of acquired von Willebrand syndrome (AvWS) in patients with heart disease is commonly perceived as rare. However, its occurrence is underestimated and underdiagnosed, potentially leading to inadequate treatment resulting in increased morbidity and mortality.In patients with cardiac disease, AvWS frequently occurs in patients with structural heart disease and in those undergoing mechanical circulatory support (MCS).The clinical manifestation of an AvWS is usually characterized by apparent or occult gastrointestinal (GI) or mucocutaneous hemorrhage frequently accompanied by signs of anemia and/or increased bleeding during surgical procedures. The primary change is loss of high-molecular weight von Willebrand factor multimers (HMWM). Whereas the loss of HMWM in patients with structural heart disease is caused by increased HMWM cleavage by von Willebrand factor (vWF)-cleaving protease, ADAMTS13, AvWS in MCS patients is predominantly a result of a high shear stress coupled ...
It is known that shoulder surgery may cause iatrogenic injury to the axillary nerve as a serious ... more It is known that shoulder surgery may cause iatrogenic injury to the axillary nerve as a serious complication, but there is little evidence to indicate whether the axillary nerve is at risk of injury during an anterolateral acromial approach for minimally-invasive plate osteosynthesis (MIPO) of proximal humerus fractures. We hypothesised that this surgical method is safe for the axillary nerve and would preserve it from iatrogenic injury. We conducted a prospective follow-up cohort study on 49 consecutive patients with proximal humerus fractures who were managed with MIPO through an anterolateral approach. All patients underwent standardised electroneurographic testing, with assessment of amplitudes of evoked compound muscle action potentials (CMAP) and distal motor latencies (DML) of the axillary nerves, pre- and post-operatively. Six weeks after injury, all patients underwent needle electromyographic (EMG) testing of anterior, middle, posterior deltoid, teres minor and paraspinal ...
3. kongres Hrvatskog društva za neurovaskularne poremećaje Hrvatskog liječeničkog zbora i Hrvatskog društva za prevenciju moždanog udara sa međunarodnim sudjelovanjem _knjiga sažetaka ; u: Liječnički vjesnik 128 (2006) (S), 2006
Tenzijska glavobolja spada u skupinu primarnih glavobolja, nedovoljno poznatog uzroka. Rizik nast... more Tenzijska glavobolja spada u skupinu primarnih glavobolja, nedovoljno poznatog uzroka. Rizik nastanka ove primarne glavobolje nije jasno defi niran kao ni tijek bolesti. Internacionalno udruženje za glavobolju klasifi ciralo je glavobolje u primarne i sekundarne. Posebnu pažnju pridaje klasifi kaciji tenzijskih glavobolja, tzv. Tension-Type Headache (TTH). Prema toj klasifi kaciji TTH se s obzirom na učestalost pojavljivanja dijeli na epizodne tenzijske glavobolje, učestale-epizodične tenzijske glavobolje te kronične tenzijske glavobolje. Nadalje, epizodične TTH dijele se s obzirom na perikranijsku napetost. Epizodične tenzijske glavobolje mogu biti rijetke (do 12 dana/godišnje) i učestale epizodične TTH koje se češće javljaju i duže traju (<15 dana/mjesec). Kronične TTH traju 15 ili više dana/ mjesec (tablica 1). Kronična TTH značajno umanjuje kvalitetu života (QOL) oboljelog zbog intenziteta boli kao i trajanja bolnog sindroma. Uz to, diferencira se i moguća TTH kao epizodična ...
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