Diabetes is a syndrome which is characterized clinically as hyperglycemia due to absolute or rela... more Diabetes is a syndrome which is characterized clinically as hyperglycemia due to absolute or relative deficiency of insulin production and progressive resistance of insulin. In recent years there is a fast increase in the occurrence and prevalence of diabetes mellitus. In the present study sphaeranthus amaranthoides was screened for antidiabetic activity in invitro. In the present search synthesis of silver phyto nanoparticles and their antidiabetic activity were studied. This is the first attempt of introducing silver herbal nanoparticles isolation and antidiabetic assessment. This is because silver nanoparticles possess a very high surface to volume ratio. This can be utilized in areas where high surface areas are critical for success. This could for example be in the catalytic industry. In biology and biochemistry nanoparticles have attracted much attention. The aim of the current work is to screen for invitro inhibition of alpha-amylase enzyme activity of extract of sphaeranthus amaranthoides silver nanoparticles. The silver nanoparticles showed a dose response inhibitory activity on α-amylase. Acarbose was used a standard drug. The IC50 value for plant extract is 0.28g/ml where as for acarbose is 0.75g/ml.
Diabetes is a syndrome which is characterized clinically as hyperglycemia due to absolute or rela... more Diabetes is a syndrome which is characterized clinically as hyperglycemia due to absolute or relative deficiency of insulin production and progressive resistance of insulin. In recent years there is a fast increase in the occurrence and prevalence of diabetes mellitus. In the present study sphaeranthus amaranthoides was screened for antidiabetic activity in invitro. In the present search synthesis of silver phyto nanoparticles and their antidiabetic activity were studied. This is the first attempt of introducing silver herbal nanoparticles isolation and antidiabetic assessment. This is because silver nanoparticles possess a very high surface to volume ratio. This can be utilized in areas where high surface areas are critical for success. This could for example be in the catalytic industry. In biology and biochemistry nanoparticles have attracted much attention. The aim of the current work is to screen for invitro inhibition of alpha-amylase enzyme activity of extract of sphaeranthus amaranthoides silver nanoparticles. The silver nanoparticles showed a dose response inhibitory activity on α-amylase. Acarbose was used a standard drug. The IC50 value for plant extract is 0.28g/ml where as for acarbose is 0.75g/ml.
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