Neurological complications of COVID-19: a systematic review
E Taherifard, E Taherifard - Neurological research, 2020 - Taylor & Francis
Neurological research, 2020•Taylor & Francis
Objectives This study aims to systematically review the neurological complications in
patients with SARS-CoV-2 infection and the methods used to diagnose both neurological
complications and coronavirus infection. Methods Data from three different online databases
(PubMed, Scopus and Web of Science) were searched on 29 April 2020 and after duplicate,
irrelevant, and inappropriate records were excluded, data extraction was done. Results The
22 records included for analysis provided 57 patients with neurological sequelae. The …
patients with SARS-CoV-2 infection and the methods used to diagnose both neurological
complications and coronavirus infection. Methods Data from three different online databases
(PubMed, Scopus and Web of Science) were searched on 29 April 2020 and after duplicate,
irrelevant, and inappropriate records were excluded, data extraction was done. Results The
22 records included for analysis provided 57 patients with neurological sequelae. The …
Objectives
This study aims to systematically review the neurological complications in patients with SARS-CoV-2 infection and the methods used to diagnose both neurological complications and coronavirus infection.
Methods
Data from three different online databases (PubMed, Scopus and Web of Science) were searched on 29 April 2020 and after duplicate, irrelevant, and inappropriate records were excluded, data extraction was done.
Results
The 22 records included for analysis provided 57 patients with neurological sequelae. The neurological complications reported ranged widely from ischemic cerebrovascular accidents to cerebral hemorrhage and were seen at both peripheral and central nervous system levels. The most frequently reported neurological complication was acute ischemic cerebrovascular accident, followed by Guillain–Barré syndrome.
Conclusions
Considering the possibility of neurological involvement in patients with SARS-CoV-2 infection can result in earlier diagnosis and treatment; otherwise permanent, irreversible sequelae and even death may follow. More comprehensive studies may indicate that until the end of the present pandemic, young adults with unexplained and unexpected stroke as well as patients with newly diagnosed Guillain–Barré syndrome should be tested for SARS-CoV-2 infection.
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