Papers by valentina panetta
Allergy, Jun 1, 2004
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Pediatric Allergy and Immunology, Nov 1, 2022
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Revue du Rhumatisme, 2019
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Clinical & Experimental Allergy, Aug 1, 2009
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The Journal of Allergy and Clinical Immunology, Sep 1, 2002
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European Journal of Pediatrics, May 30, 2023
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Research Square (Research Square), Jul 6, 2021
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Case Medical Research, 2019
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Journal of investigational allergology & clinical immunology, 2009
Atopic dermatitis is a common disease in children. It is usually treated with topical steroids an... more Atopic dermatitis is a common disease in children. It is usually treated with topical steroids and/or calcineurin inhibitors in association with emollients but topical antioxidants have been recently introduced as a therapeutic option for children. The aim of this study was to evaluate the efficacy and tolerability of furfuryl palmitate, a new antioxidant molecule, in a multicenter, randomized, double-blind, vehicle-controlled study. Children with atopic dermatitis were randomized into 2 groups treated for 2 weeks. One group of children (n = 60) was treated with a basic emollient cream and the other (n = 57) was treated with the same cream enriched with furfuryl palmitate. In both groups, there was a significant reduction (P < .001) in atopic dermatitis-measured using the SCORAD index-after 14 days. The reduction in the per-protocol analysis was higher for the basic cream. Treatment success was defined as a reduction of 20% or more in the SCORAD index from baseline to day 14. Pat...
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Cancers
Background: For non-muscle-invasive bladder cancer (NMIBC) requiring radical surgery, limited dat... more Background: For non-muscle-invasive bladder cancer (NMIBC) requiring radical surgery, limited data are available comparing robotic-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) to open radical cystectomy (ORC). The objective of this study was to compare the two surgical techniques. Methods: A multicentric cohort of 593 patients with NMIBC undergoing iRARC or ORC between 2015 and 2020 was prospectively gathered. Perioperative and pathologic outcomes were compared. Results: A total of 143 patients operated on via iRARC were matched to 143 ORC patients. Operative time was longer in the iRARC group (p = 0.034). Blood loss was higher in the ORC group (p < 0.001), with a consequent increased post-operative transfusion rate in the ORC group (p = 0.003). Length of stay was longer in the ORC group (p = 0.007). Post-operative complications did not differ significantly (all p > 0.05). DFS at 60 months was 55.9% in ORC and 75.2% in iRARC with a statistically si...
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Digestive and Liver Disease
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Hepatology, 2021
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British Journal of Surgery, 2021
Background Laparoscopic liver resection for hepatocellular carcinoma (HCC) in Child–Pugh A cirrho... more Background Laparoscopic liver resection for hepatocellular carcinoma (HCC) in Child–Pugh A cirrhosis has been demonstrated as beneficial. However, the role of laparoscopy in Child–Pugh B cirrhosis is undetermined. The aim of this retrospective cohort study was to compare open and laparoscopic resection for HCC with Child–Pugh B cirrhosis. Methods Data on liver resections were gathered from 17 centres. A 1 : 1 propensity score matching was performed according to 17 predefined variables. Results Of 382 available liver resections, 100 laparoscopic and 100 open resections were matched and analysed. The 90-day postoperative mortality rate was similar in open and laparoscopic groups (4.0 versus 2.0 per cent respectively; P = 0.687). Laparoscopy was associated with lower blood loss (median 110 ml versus 400 ml in the open group; P = 0.004), less morbidity (38.0 versus 51.0 per cent respectively; P = 0.041) and fewer major complications (7.0 versus 21.0 per cent; P = 0.010), and ascites was...
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Clinical Microbiology and Infection, 2011
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Frontiers in Psychology
BackgroundEvidence suggests that organizational models that provide care interventions including ... more BackgroundEvidence suggests that organizational models that provide care interventions including patient support programs may increase patient adherence to multiple sclerosis (MS) therapies by providing tailored symptom management, informational support, psychological and/or social support, lifestyle changes, emotional adjustment, health education, and tailored coaching, thus improving patients' overall quality of life across the disease course.ObjectiveThe main objective of this study was to describe MS patients' self-reported experience of a nurse-led, telephone-based PSP and to explore its potential role in improving disease and therapy management skills.MethodsSurvey data were analyzed from a subset of patients relapsing–remitting MS (RRMS) using interferon beta-1a already registered in the adveva® PSP from three Italian multiple sclerosis centers with a consolidated experience in RRMS disease, treatment management, and PSP programs.ResultsIn total, 244 patient data at b...
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Frontiers in Neurology
BackgroundIn multiple sclerosis (MS), bridging therapies are usually administered when switching ... more BackgroundIn multiple sclerosis (MS), bridging therapies are usually administered when switching from one therapy to another. Such treatments generally consist of injectable immunomodulatory drugs (interferon or glatiramer acetate), whose efficacy, safety, and tolerability data are consolidated for use even in fragile patients. We performed a nationwide survey to gather expert opinions regarding the most appropriate use of bridging therapies in MS.MethodsAn independent steering committee of Italian neurologists with expertise in MS treatment identified critical issues in the use of bridging therapies and formulated a questionnaire. This questionnaire was used to conduct a Delphi web survey, involving a panel of Italian neurologists with experience in MS treatment. Their anonymous opinions were collected in three sequential rounds. Consensus was defined as an interquartile range (IQR) ≤2.ResultsResponses were obtained from 38 experts (100%) in all three rounds. Injectable immunomodul...
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Frontiers in Immunology
ObjectiveTo evaluate the mean increase of anti-S IgG antibody titer between the basal, pre-booste... more ObjectiveTo evaluate the mean increase of anti-S IgG antibody titer between the basal, pre-booster level to the titer assessed 14 days after the booster dose of BNT162b2.Patients and MethodsThe RENAISSANCE study is an observational, longitudinal, prospective, population-based study, conducted on healthcare workers of Niguarda Hospital in Milan, Italy who received a BNT162b2 booster dose at least 180 days after their second dose or after positivity for SARS-CoV-2 and accepted to take part in the study. The RENAISSANCE study was conducted from January 1, 2021 through December 28, 2021.Findings1,738 subjects were enrolled among healthcare workers registered for the booster administration at our hospital. Overall, 0.4% of subjects were seronegative at the pre-booster evaluation, and 1 subject had a titer equal to 50 AU/ml: none of the evaluated subjects was seronegative after the booster dose. Thus, the efficacy of the booster in our population was universal. Mean increase of pre- to po...
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Social Science Research Network, 2021
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allergologia 15 Gli Autori dichiarano di non avere alcun conflitto di interesse rispetto agli arg... more allergologia 15 Gli Autori dichiarano di non avere alcun conflitto di interesse rispetto agli argomenti trattati nell'articolo. Abstract Background. La diagnosi di allergia alle proteine del latte vaccino (APLV) IgE-mediata si basa spesso su una storia clinica compatibile e sui risultati di test in vivo (skin prick test, SPT) o in vitro (ricerca di IgE specifiche, sIgE). Come gli SPT, anche la ricerca delle sIgE presenta una buona sensibilità ma una bassa specificità, cioè risulta spesso positiva in soggetti non al-lergici. Per questo motivo il TPO rimane ancora il gold standard per la diagnosi, nonostante i costi e i rischi per il paziente. L'obiettivo del presente lavoro è quello di effettuare una revi-sione sistematica della letteratura in modo da identificare, analizzare e valutare tutti gli studi che hanno proposto un valore predittivo delle sIgE per il latte vaccino e per le sue principali molecole allergeniche individuando, nel contempo, dei valori di cutoff utili per...
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Papers by valentina panetta