Papers by fernando olavarria
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Forum Qualitative Sozialforschung Forum Qualitative Social Research, Nov 15, 2013
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Rev Chil Pediatr, Aug 1, 1988
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Revista Katalysis, 2012
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Revista Chilena De Pediatria, Apr 1, 1990
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Clin Pediat, 1987
A prospective study of full-term infants with neonatal asphyxia was performed to evaluate possibl... more A prospective study of full-term infants with neonatal asphyxia was performed to evaluate possible alterations in renal function. Twenty-one newborns with an Apgar score less than or equal to 3 at 1 minute after birth and a control group of 20 normal infants were included. Oliguria of 12 hours or more (less than 1 ml/Kg/h) during the first 24 hours after birth was considered indication for a volume challenge test and use of diuretic. The study of renal function was effected between 24 and 48 hours after birth for asphyxiated and control infants (Period I), and was repeated between 48 and 72 hours (Period II) for the asphyxiated group only. Intrinsic acute renal failure was diagnosed in two patients, one of whom died. In 10 cases, prerenal oliguria responded promptly to volume expansion with improvement of biochemical indices in Period II. In nine cases, urine volume was not altered, and all functional parameters were comparable with those of control.
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Andamios Revista De Investigacion Social, 2013
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Advances in experimental medicine and biology, 1993
Sera from 210 patients with APSGN, were tested for the presence of ANCA (IgG-isotype). Indirect i... more Sera from 210 patients with APSGN, were tested for the presence of ANCA (IgG-isotype). Indirect immunofluorescence (IF) on ethanol fixed human PMNs was used, and for those positive sera, ELISA kits for PR3 (Proteinase 3) and MPO (Myeloperoxidase) was performed. ANCA were detected in 9% (18 out of 210 cases) in a predominantly diffuse cytoplasmic staining pattern in 14 cases (77%), and in a perinuclear pattern in the remaining 4 cases (22%). Anti-MPO was found in 4 cases (C-ANCA 3; P-ANCA 1) and anti-PR3 was always negative. The presence of ANCA was significantly associated with a more severe glomerular disease as assessed by the serum creatinine value and the crescents formation. Longitudinal studies performed in 11 cases have shown that raised levels of these autoantibodies may persist for at least six months, without relationship with disease activity. Further studies are required to dilucidate the specificity of these autoantibodies, and if its presence is either an epiphenomenon...
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Revista Katálysis, 2012
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Revista Katálysis, 2014
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Revista chilena de pediatría, 1975
Desde que el Grupo Cooperativo Internacio-nal de Enfermedades Renales en el Nino se abo-co al est... more Desde que el Grupo Cooperativo Internacio-nal de Enfermedades Renales en el Nino se abo-co al estudio del Sindrome Nefrotico Idiopatico, numerosos investigadores nacionales y extranjeros (1) (6) (11) (12), han adoptado sus normas en cuanto a clasificacion ...
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Revista chilena de pediatría, 1983
... Dr. Sergio Krause H. , Sr. Antonio Rivas B. Dr. Fernando Olavarria U. Sra. Gester Perdiguero ... more ... Dr. Sergio Krause H. , Sr. Antonio Rivas B. Dr. Fernando Olavarria U. Sra. Gester Perdiguero N. y Srta. Nora Leal A. Serum Copper Levels in newbron infants ... Am. J. Gin. Nutr. 35(4): 809, 1982.Al - Rashid, R^A; Spangler, J.: Neonatal copper deficiency. New Eng. ...
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Revista chilena de pediatría, 1975
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Nephron, 1989
In an attempt to further study the possible contribution of circulating immune complexes (CIC) in... more In an attempt to further study the possible contribution of circulating immune complexes (CIC) in the pathogenesis of the classic form of hemolytic uremic syndrome, 9 patients were studied during the acute phase of the diseases. C1q solid-phase ELISA and conglutinin solid-phase ELISA, were used to measure the levels of immune complexes. All 9 were positive in one or both assays. No correlation was found between the levels of CIC and the clinical severity of the disease. The constant finding of positive CIC in these patients might represent an epiphenomenon, point out the postinfectious nature of this disease but also suggest a possible pathogenic role.
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Nephron, 1991
The Fc-receptor function of the mononuclear phagocyte system (MPS) was examined in 41 children an... more The Fc-receptor function of the mononuclear phagocyte system (MPS) was examined in 41 children and adult patients, by measuring the clearance of IgG-sensitized, 51Cr-labeled erythrocytes. The Fc-receptor-mediated clearance observed in patients (mean +/- SE) was not significantly different as compared to the control group of similar age distribution. However, the immune clearance time was significantly age-correlated in both groups (acute poststreptococcal glomerulonephritis, APSGN, r = 0.39, p less than 0.05; control r = 0.63, p less than 0.01). The magnitude of the Fc-specific immune clearance and the serum creatinine were also significantly correlated (r = 0.59; p less than 0.01). Circulating immune complexes (as measured by the C1q and conglutinin ELISA) did not correlate with immune clearance, which remained stable in longitudinal studies. Age-related changes in MPS Fc-receptor function could explain, at least in part, prognostic differences between children and adult patients with APSGN.
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Nephron, 1994
Circulating immune complexes (CIC) have been described in the hemolytic uremic syndrome (HUS) in ... more Circulating immune complexes (CIC) have been described in the hemolytic uremic syndrome (HUS) in children. They may represent an epiphenomenon or could be related to the platelet activation and endothelial damage observed in this disease. In an attempt to define this relationship, we investigated the CIC isolated in 17 patients with the classic form of HUS, by means of monoclonal antibodies against platelet surface glycoprotein Ib and IIb-IIIa complex. The negative results obtained do not support the possibility of platelet antigens being constituents of CIC and make an antibody-induced platelet activation in HUS very unlikely.
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