This study determined Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium surviv... more This study determined Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium survival on tomato skins as a function of sanitization treatment, under three differing contamination and sanitization scenarios. Sanitizing treatments consisted of the plant-derived antimicrobial (PDA) geraniol (0.5 wt.%) emulsified in the polymeric surfactant Pluronic F-127 (GNP), 0.5 wt.% unencapsulated geraniol (UG), 200 mg/L hypochlorous acid at pH 7.0 (HOCl), and a sterile distilled water wash (CON). Experimental contamination and sanitization scenarios tested were: (1) pathogen inoculation preceded by treatment; (2) the pathogen was inoculated onto samples twice with a sanitizing treatment applied in between inoculations; and (3) pathogen inoculation followed by sanitizing treatment. Reductions in counts of surviving pathogens were dependent on the sanitizing treatment, the storage period, or the interaction of these independent/main effects. GNP treatment yielded the greatest reduction...
Concerns arising from accidental and occasional releases of novel industrial nanomaterials to the... more Concerns arising from accidental and occasional releases of novel industrial nanomaterials to the environment and waterbodies are rapidly increasing as the production and utilization levels of nanomaterials increase every day. In particular, two-dimensional nanosheets are one of the most significant emerging classes of nanomaterials used or considered for use in numerous applications and devices. This study deals with the interactions between 2D molybdenum disulfide (MoS2) nanosheets and beneficial soil bacteria. It was found that the log-reduction in the survival of Gram-positive Bacillus cereus was 2.8 (99.83%) and 4.9 (99.9988%) upon exposure to 16.0 mg/mL bulk MoS2 (macroscale) and 2D MoS2 nanosheets (nanoscale), respectively. For the case of Gram-negative Pseudomonas aeruginosa, the log-reduction values in bacterial survival were 1.9 (98.60%) and 5.4 (99.9996%) for the same concentration of bulk MoS2 and MoS2 nanosheets, respectively. Based on these findings, it is important to...
Sustainable Materials for Transitional and Alternative Energy, 2021
Abstract Over the last few decades, increasing demand for gas and oil industries has compelled ne... more Abstract Over the last few decades, increasing demand for gas and oil industries has compelled new design and enhanced drilling technologies that squeeze more from available energy sources and enable new energy resources. To address this challenge, smart and state-of-arts materials become promising alternative solid-state actuator for pneumatic, conventional hydraulic, and motor-based actuators due to their remarkable properties such as corrosion resistance, lightweight, superelasticity, and shape memory effect (SME). Furthermore, the demand for more effective chemicals will increase during the forecast period as companies meet the challenges of more extreme conditions, such as deep offshore deposits, that will alter the performance characteristics and effectiveness of chemicals required to work effectively in these environments. Many chemicals that are used today will be replaced with more multifunctional chemicals and processes that enable the reuse and recycle of material generated in more remote and isolated locations. In this chapter, smarts materials and state-of-art materials explained under two main sections. The additives and nanoparticles (NPs) are covered under the state-of-art materials section. This section will provide a better understanding of areas with growth potential as well as areas of additives and NPs. Moreover, piezoelectric and shape memory materials are employed in ultrasonic bore-hole imaging, sonic logging-while-drilling, precision pressure measurement and marine seismic survey, and explained under smart materials section. Smart and state-of-art materials find application in subsea pumps, self-torquing fasteners, reconfigurable seals, the underwater connectors, deep water valves and other adaptive components. Finally, detail information of the supramolecular assembly solutions is given in this chapter. This chapter will cover recent developments, challenges and application of shape memory materials in the energy, oil and gas industries.
Protecting fresh-packed produce microbiological safety against pre- and post-harvest microbial pa... more Protecting fresh-packed produce microbiological safety against pre- and post-harvest microbial pathogen contamination requires innovative antimicrobial strategies. Although largely ignored in the scientific literature, there exists the potential for gross failure in food safety protection of fresh fruits and vegetables leading to opportunity for multiple produce contamination events to occur during production and post-harvest handling of food crops. The primary objective of this research was to determine the efficacy of plant-derived antimicrobial-loaded nanoparticles to reduce Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium on spinach leaf surfaces whilst simulating multiple pathogen contamination events (pre-harvest and post-harvest). Spinach samples were inoculated with a blend of E. coli O157:H7 and S. Typhimurium, each diluted to ~8.0 log10 CFU/mL. The inoculated samples were then submerged in solutions containing nanoparticles loaded with geraniol (GPN; 0....
This study aimed to quantify survival in Escherichia coli O157:H7 and Salmonella enterica serovar... more This study aimed to quantify survival in Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium isolates on melon rind surface samples achieved by sanitizer treatment under three differing melon contamination and sanitization scenarios. Sanitizing treatments consisted of the plant-derived antimicrobial (PDA) essential oil component (EOC) geraniol (0.5 wt.%) entrapped in the polymeric surfactant Pluronic F-127 (GNP), 0.5 wt.% unencapsulated geraniol (UG), 200 mg/L hypochlorous acid at pH 7.0 (HOCl), and a sterile distilled water wash (CON). The experimental contamination and sanitization scenarios tested were: (1) pathogen inoculation preceded by treatment; (2) the pathogen was inoculated onto samples twice with sanitizing treatment applied in between inoculation events; or (3) pathogen inoculation followed by sanitizing treatment. Reductions in the numbers of surviving pathogens were dependent on the sanitizing treatment, the storage period, or the interaction of these...
Abstract Foodborne illness outbreaks caused by bacterial pathogens may take place on a large scal... more Abstract Foodborne illness outbreaks caused by bacterial pathogens may take place on a large scale and result in millions of hospitalizations and thousands of deaths every year throughout the world. One key strategy for dealing with this global issue is the design of smart surfaces and coatings which inhibit and reduce bacterial attachment. This can mitigate contamination and cross-contamination during farm-to-table food processing, promoting food safety, and hygiene. Herein, we reported a durable superhydrophobic coating on aluminum surfaces fabricated by sequential deposition of ultrahard nanodiamond, self-assembly of l-3,4-dihydroxyphenylalanine ( l -dopamine), and chemical modification with an organoflurosilane. This coating achieved static, advancing, and receding water contact angles of 159.0 ± 2.5°,154.0 ± 2.4°; and 153.7 ± 1.7°, respectively, representing water super-repellency with a low overall root mean square (rms) roughness of 173.5 ± 69.6 nm. In comparison to the bare, unmodified aluminum, the coated aluminum surfaces prevented the attachment of 99.5% of applied Escherichia coli O157:H7 (E.coli O157:H7) and 99.0% of Staphylococcus aureus (S. aureus) cells. In addition, due to the presence of nanodiamond building blocks, the coated surfaces demonstrated a high mechanical resistance against scratching and endured at least 10,000 shearing/rubbing cycles with a nylon surface. Overall, we anticipate that implementation of this coating could improve safety and hygiene of food-contact surfaces that require harsher mechanical operational conditions.
Cetylpyridinium chloride (CPC) is a quaternary ammonium sanitizer approved for fresh poultry anim... more Cetylpyridinium chloride (CPC) is a quaternary ammonium sanitizer approved for fresh poultry animal carcass sanitization from microbial human pathogens, such as Salmonella enterica. Nonetheless, the interactions of CPC with Salmonella cells, and the mechanism of the sanitizer’s neutralization by lecithin remains largely unknown. This study aimed to investigate the interaction of CPC with lecithin and Salmonella Typhimurium to determine the interactions of the sanitizer and neutralizer impacting the bacterium’s survival. Application of 0.8% CPC is proposed to produce loss of microbial membrane integrity with loss of electrostatic repulsion between individual cells, resulting in the eventual emulsification of membrane lipids with cytoplasmic contents leakage. Our findings point to a two-phase interaction between CPC and lecithin impacting S. Typhimurium survival. The first consists of electrostatic attraction and charge neutralization between oppositely charged components of pathogen ...
Abu Dhabi International Petroleum Exhibition & Conference, 2017
Hydraulic fracturing is an important method to recover shale oil and gas that has drastically inc... more Hydraulic fracturing is an important method to recover shale oil and gas that has drastically increased U.S. energy production in recent decades. Shales are low permeability formations where natural resources are trapped, and require a well-planned hydraulic fracturing process and a highly developed fracturing (fracking) fluid for efficient oil/gas recovery. In this study, a pH-responsive solution synthesized by supramolecular assembly of maleic acid and an amino-amide in an aqueous media is described as a potential fracking fluid owing to its mobility control, proppant carrying and settling capacities. Previous investigations on this solution system had shown its large potential to replace displacement fluids in EOR due to pH-tunable and reversible viscosity behavior. The main working mechanism is that; the initial viscosity of injected solution is kept at moderate/high values to easily transport proppants and easily inject the fluid; and then decreased when the solution reaches a ...
This work is concerned with investigating the effect of substrate hydrophobicity and zeta potenti... more This work is concerned with investigating the effect of substrate hydrophobicity and zeta potential on the dynamics and kinetics of the initial stages of bacterial adhesion. For this purpose, bacterial pathogens Staphylococcus aureus and Escherichia coli O157:H7 were inoculated on the substrates coated with thin thiol layers (i.e., 1-octanethiol, 1-decanethiol, 1-octadecanethiol, 16-mercaptohexadecanoic acid, and 2-aminoethanethiol hydrochloride) with varying hydrophobicity and surface potential. The time-resolved adhesion data revealed a transformation from an exponential dependence to a square root dependence on time upon changing the substrate from hydrophobic or hydrophilic with a negative zeta potential value to hydrophilic with a negative zeta potential for both pathogens. The dewetting of extracellular polymeric substances (EPS) produced by E. coli O157:H7 was more noticeable on hydrophobic substrates, compared to that of S. aureus, which is attributed to the more amphiphilic...
Nanomedicines, compared to traditional medicines, can cause enhanced toxicity on algae owing to t... more Nanomedicines, compared to traditional medicines, can cause enhanced toxicity on algae owing to their ability to solubilize water-insoluble drug molecules.
Herein, a single-step, scalable approach for preparing a multifunctional, theranostic drug delive... more Herein, a single-step, scalable approach for preparing a multifunctional, theranostic drug delivery system made out of paclitaxel, iron oxide nanoparticles, gold nanoparticles, and poly(ethylene oxide)-b-poly(ε-caprolactone) is reported.
The contamination of the environment with traditional therapeutics due to metabolic excretion, im... more The contamination of the environment with traditional therapeutics due to metabolic excretion, improper disposal, and industrial waste has been well-recognized. However, knowledge of the environmental distribution and fate of emerging classes of nanomedicine is scarce. This work investigates the effect of surface chemistry of polymeric nanoparticulate drug delivery systems (PNDDS) on their adsorption dynamics and transport in the vicinity of environmentally relevant surfaces for a concentration comparable with hospital and pharmaceutical manufacturing effluents. To this end, five different types of paclitaxel-based nanomedicine having different polymer stabilizers were employed. Their transport behavior was characterized via quartz crystal microbalance, sand column, spectrofluorometry, and dynamic light scattering techniques. PNDDS having positive zeta-potential displayed strong adsorption onto silica surfaces and no mobility in porous media of quartz sand, even in the presence of h...
This study determined Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium surviv... more This study determined Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium survival on tomato skins as a function of sanitization treatment, under three differing contamination and sanitization scenarios. Sanitizing treatments consisted of the plant-derived antimicrobial (PDA) geraniol (0.5 wt.%) emulsified in the polymeric surfactant Pluronic F-127 (GNP), 0.5 wt.% unencapsulated geraniol (UG), 200 mg/L hypochlorous acid at pH 7.0 (HOCl), and a sterile distilled water wash (CON). Experimental contamination and sanitization scenarios tested were: (1) pathogen inoculation preceded by treatment; (2) the pathogen was inoculated onto samples twice with a sanitizing treatment applied in between inoculations; and (3) pathogen inoculation followed by sanitizing treatment. Reductions in counts of surviving pathogens were dependent on the sanitizing treatment, the storage period, or the interaction of these independent/main effects. GNP treatment yielded the greatest reduction...
Concerns arising from accidental and occasional releases of novel industrial nanomaterials to the... more Concerns arising from accidental and occasional releases of novel industrial nanomaterials to the environment and waterbodies are rapidly increasing as the production and utilization levels of nanomaterials increase every day. In particular, two-dimensional nanosheets are one of the most significant emerging classes of nanomaterials used or considered for use in numerous applications and devices. This study deals with the interactions between 2D molybdenum disulfide (MoS2) nanosheets and beneficial soil bacteria. It was found that the log-reduction in the survival of Gram-positive Bacillus cereus was 2.8 (99.83%) and 4.9 (99.9988%) upon exposure to 16.0 mg/mL bulk MoS2 (macroscale) and 2D MoS2 nanosheets (nanoscale), respectively. For the case of Gram-negative Pseudomonas aeruginosa, the log-reduction values in bacterial survival were 1.9 (98.60%) and 5.4 (99.9996%) for the same concentration of bulk MoS2 and MoS2 nanosheets, respectively. Based on these findings, it is important to...
Sustainable Materials for Transitional and Alternative Energy, 2021
Abstract Over the last few decades, increasing demand for gas and oil industries has compelled ne... more Abstract Over the last few decades, increasing demand for gas and oil industries has compelled new design and enhanced drilling technologies that squeeze more from available energy sources and enable new energy resources. To address this challenge, smart and state-of-arts materials become promising alternative solid-state actuator for pneumatic, conventional hydraulic, and motor-based actuators due to their remarkable properties such as corrosion resistance, lightweight, superelasticity, and shape memory effect (SME). Furthermore, the demand for more effective chemicals will increase during the forecast period as companies meet the challenges of more extreme conditions, such as deep offshore deposits, that will alter the performance characteristics and effectiveness of chemicals required to work effectively in these environments. Many chemicals that are used today will be replaced with more multifunctional chemicals and processes that enable the reuse and recycle of material generated in more remote and isolated locations. In this chapter, smarts materials and state-of-art materials explained under two main sections. The additives and nanoparticles (NPs) are covered under the state-of-art materials section. This section will provide a better understanding of areas with growth potential as well as areas of additives and NPs. Moreover, piezoelectric and shape memory materials are employed in ultrasonic bore-hole imaging, sonic logging-while-drilling, precision pressure measurement and marine seismic survey, and explained under smart materials section. Smart and state-of-art materials find application in subsea pumps, self-torquing fasteners, reconfigurable seals, the underwater connectors, deep water valves and other adaptive components. Finally, detail information of the supramolecular assembly solutions is given in this chapter. This chapter will cover recent developments, challenges and application of shape memory materials in the energy, oil and gas industries.
Protecting fresh-packed produce microbiological safety against pre- and post-harvest microbial pa... more Protecting fresh-packed produce microbiological safety against pre- and post-harvest microbial pathogen contamination requires innovative antimicrobial strategies. Although largely ignored in the scientific literature, there exists the potential for gross failure in food safety protection of fresh fruits and vegetables leading to opportunity for multiple produce contamination events to occur during production and post-harvest handling of food crops. The primary objective of this research was to determine the efficacy of plant-derived antimicrobial-loaded nanoparticles to reduce Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium on spinach leaf surfaces whilst simulating multiple pathogen contamination events (pre-harvest and post-harvest). Spinach samples were inoculated with a blend of E. coli O157:H7 and S. Typhimurium, each diluted to ~8.0 log10 CFU/mL. The inoculated samples were then submerged in solutions containing nanoparticles loaded with geraniol (GPN; 0....
This study aimed to quantify survival in Escherichia coli O157:H7 and Salmonella enterica serovar... more This study aimed to quantify survival in Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium isolates on melon rind surface samples achieved by sanitizer treatment under three differing melon contamination and sanitization scenarios. Sanitizing treatments consisted of the plant-derived antimicrobial (PDA) essential oil component (EOC) geraniol (0.5 wt.%) entrapped in the polymeric surfactant Pluronic F-127 (GNP), 0.5 wt.% unencapsulated geraniol (UG), 200 mg/L hypochlorous acid at pH 7.0 (HOCl), and a sterile distilled water wash (CON). The experimental contamination and sanitization scenarios tested were: (1) pathogen inoculation preceded by treatment; (2) the pathogen was inoculated onto samples twice with sanitizing treatment applied in between inoculation events; or (3) pathogen inoculation followed by sanitizing treatment. Reductions in the numbers of surviving pathogens were dependent on the sanitizing treatment, the storage period, or the interaction of these...
Abstract Foodborne illness outbreaks caused by bacterial pathogens may take place on a large scal... more Abstract Foodborne illness outbreaks caused by bacterial pathogens may take place on a large scale and result in millions of hospitalizations and thousands of deaths every year throughout the world. One key strategy for dealing with this global issue is the design of smart surfaces and coatings which inhibit and reduce bacterial attachment. This can mitigate contamination and cross-contamination during farm-to-table food processing, promoting food safety, and hygiene. Herein, we reported a durable superhydrophobic coating on aluminum surfaces fabricated by sequential deposition of ultrahard nanodiamond, self-assembly of l-3,4-dihydroxyphenylalanine ( l -dopamine), and chemical modification with an organoflurosilane. This coating achieved static, advancing, and receding water contact angles of 159.0 ± 2.5°,154.0 ± 2.4°; and 153.7 ± 1.7°, respectively, representing water super-repellency with a low overall root mean square (rms) roughness of 173.5 ± 69.6 nm. In comparison to the bare, unmodified aluminum, the coated aluminum surfaces prevented the attachment of 99.5% of applied Escherichia coli O157:H7 (E.coli O157:H7) and 99.0% of Staphylococcus aureus (S. aureus) cells. In addition, due to the presence of nanodiamond building blocks, the coated surfaces demonstrated a high mechanical resistance against scratching and endured at least 10,000 shearing/rubbing cycles with a nylon surface. Overall, we anticipate that implementation of this coating could improve safety and hygiene of food-contact surfaces that require harsher mechanical operational conditions.
Cetylpyridinium chloride (CPC) is a quaternary ammonium sanitizer approved for fresh poultry anim... more Cetylpyridinium chloride (CPC) is a quaternary ammonium sanitizer approved for fresh poultry animal carcass sanitization from microbial human pathogens, such as Salmonella enterica. Nonetheless, the interactions of CPC with Salmonella cells, and the mechanism of the sanitizer’s neutralization by lecithin remains largely unknown. This study aimed to investigate the interaction of CPC with lecithin and Salmonella Typhimurium to determine the interactions of the sanitizer and neutralizer impacting the bacterium’s survival. Application of 0.8% CPC is proposed to produce loss of microbial membrane integrity with loss of electrostatic repulsion between individual cells, resulting in the eventual emulsification of membrane lipids with cytoplasmic contents leakage. Our findings point to a two-phase interaction between CPC and lecithin impacting S. Typhimurium survival. The first consists of electrostatic attraction and charge neutralization between oppositely charged components of pathogen ...
Abu Dhabi International Petroleum Exhibition & Conference, 2017
Hydraulic fracturing is an important method to recover shale oil and gas that has drastically inc... more Hydraulic fracturing is an important method to recover shale oil and gas that has drastically increased U.S. energy production in recent decades. Shales are low permeability formations where natural resources are trapped, and require a well-planned hydraulic fracturing process and a highly developed fracturing (fracking) fluid for efficient oil/gas recovery. In this study, a pH-responsive solution synthesized by supramolecular assembly of maleic acid and an amino-amide in an aqueous media is described as a potential fracking fluid owing to its mobility control, proppant carrying and settling capacities. Previous investigations on this solution system had shown its large potential to replace displacement fluids in EOR due to pH-tunable and reversible viscosity behavior. The main working mechanism is that; the initial viscosity of injected solution is kept at moderate/high values to easily transport proppants and easily inject the fluid; and then decreased when the solution reaches a ...
This work is concerned with investigating the effect of substrate hydrophobicity and zeta potenti... more This work is concerned with investigating the effect of substrate hydrophobicity and zeta potential on the dynamics and kinetics of the initial stages of bacterial adhesion. For this purpose, bacterial pathogens Staphylococcus aureus and Escherichia coli O157:H7 were inoculated on the substrates coated with thin thiol layers (i.e., 1-octanethiol, 1-decanethiol, 1-octadecanethiol, 16-mercaptohexadecanoic acid, and 2-aminoethanethiol hydrochloride) with varying hydrophobicity and surface potential. The time-resolved adhesion data revealed a transformation from an exponential dependence to a square root dependence on time upon changing the substrate from hydrophobic or hydrophilic with a negative zeta potential value to hydrophilic with a negative zeta potential for both pathogens. The dewetting of extracellular polymeric substances (EPS) produced by E. coli O157:H7 was more noticeable on hydrophobic substrates, compared to that of S. aureus, which is attributed to the more amphiphilic...
Nanomedicines, compared to traditional medicines, can cause enhanced toxicity on algae owing to t... more Nanomedicines, compared to traditional medicines, can cause enhanced toxicity on algae owing to their ability to solubilize water-insoluble drug molecules.
Herein, a single-step, scalable approach for preparing a multifunctional, theranostic drug delive... more Herein, a single-step, scalable approach for preparing a multifunctional, theranostic drug delivery system made out of paclitaxel, iron oxide nanoparticles, gold nanoparticles, and poly(ethylene oxide)-b-poly(ε-caprolactone) is reported.
The contamination of the environment with traditional therapeutics due to metabolic excretion, im... more The contamination of the environment with traditional therapeutics due to metabolic excretion, improper disposal, and industrial waste has been well-recognized. However, knowledge of the environmental distribution and fate of emerging classes of nanomedicine is scarce. This work investigates the effect of surface chemistry of polymeric nanoparticulate drug delivery systems (PNDDS) on their adsorption dynamics and transport in the vicinity of environmentally relevant surfaces for a concentration comparable with hospital and pharmaceutical manufacturing effluents. To this end, five different types of paclitaxel-based nanomedicine having different polymer stabilizers were employed. Their transport behavior was characterized via quartz crystal microbalance, sand column, spectrofluorometry, and dynamic light scattering techniques. PNDDS having positive zeta-potential displayed strong adsorption onto silica surfaces and no mobility in porous media of quartz sand, even in the presence of h...
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