The intelligrid-oriented on-line relay settings verification system based on EMS real-time data a... more The intelligrid-oriented on-line relay settings verification system based on EMS real-time data are discussed, with related software system designed and fulfilled. Firstly, the research background and current situation of on-line relay settings verification system are summarized. Secondly, the on-line relay settings verification system's general principle, hardware and software design are mainly discussed. And this paper shows the designed hardware structure diagram, the software structure diagram. And the flowchart of main procedure is given. Thirdly, the methods of dealing with EMS real-time data of the on-line verification system are discussed in detail. The verifying principles of sensitivity & selectivity of relay protection are given definitely. It is able to simulate two simultaneous faults, faults in network oscillation, and faults during auto-reclosing. It checks reliability & sensitivity of relay settings under these circumstances. Finally, considering substation-area and wide-area relay protections, this paper points out some key problems of on-line relay settings verification system to be resolved, and its application prospect.
Bernard Lonergan (1904-1984), the accomplished theologian and philosopher, successfully demonstra... more Bernard Lonergan (1904-1984), the accomplished theologian and philosopher, successfully demonstrated an invariant pattern in human understanding which could be appropriated not only in the cognitional structure but also applied to the field of metaphysics. On the other hand, one of the most influential thinkers in modern China, Chu Hsi(朱熹, 1130-1200)developed an original and mature theory named “study of the underlying principles to acquire knowledge” .(ko wu chih chih,,格物致知)It is generally agreed in China that this is one of the most important cognitional theories. I believe both of them share profound similarities especially in the notions of “insight” and so call “sudden Integration” (huo ran guan tong, 豁然貫通)This paper is divided into four main sections. In the first place, I will introduce both of them especially on their academic or cultural background. Secondly, I will argue that Lonergan distinguished isomorphism between knowing and known is comparative with Chu Hsi’s affirmation between the “reason of the human mind” and the “reason of things”. Thirdly, I will analysis both Lonergan’s notion of insight and Chu His’s sudden Integration. Finally, I will distinguish some similarities and discrimination in their philosophies.
Abstract Graphene gains lots of methodical and scientific interests since graphene and its deriva... more Abstract Graphene gains lots of methodical and scientific interests since graphene and its derivatives bring new perspectives and prospects into electrochemical systems. The two-dimensional (2D) material possesses unique physicochemical properties, including high surface area, excellent conductivity, high mechanical strength, ease of functionalization, and mass production. In the past decade, the usage of graphene as a sensor element in miniaturized and biomedical sensor devices is increasing. Including graphene, graphene oxide, and hybrid nanocomposites into electrode modification processes has been shown to improve detection sensitivity and advance electrocatalytic behavior. The overall aim of this chapter is to provide a brief overview of recent advances in applying graphene-based materials into electrochemical sensor for biomedical applications. In particular, graphene-based biosensors for small molecule, protein, nucleic acid, and cell analyses are addressed.
Journal of Mechanics in Medicine and Biology, Dec 1, 2015
Reconstruction of the condyle after an ablative procedure for mouth neoplasms remains a surgical ... more Reconstruction of the condyle after an ablative procedure for mouth neoplasms remains a surgical challenge because these patients with advanced cancer involving the condyle are subjected to massive ablative surgery, and subsequent major reconstruction with free flap and/or reconstruction prosthesis, the prognosis being poor. Therefore, reports of condylar prosthesis in head and neck cancer reconstruction are rare and with mixed results. This report is for the review of the literature and case series study of the condylar prosthesis. As with virtual technique improvement nowadays, an innovation CAD CAM technique is applied for the treatment plan for these patients. We analyze a serial case of advanced oral neoplasms who receives tumor ablation, i.e., mandibulectomy and disarticular resection, and gains symmetrical mandibular architecture after reconstruction with plate and condylar prosthesis. There is still high complication rate (41.7%) noted, namely condylar prosthesis displacement (two cases), impinge on external ear canal (two cases), and erosion of cranial base (one case). The reasons are attributed to massive flap burden, scar contraction, poor dental articulation, and possible technique error during the operation. According to the outcome analysis, virtual technique including with reconstruction plate and condylar prosthesis in conjunction with flap reconstruction are feasible treatment modality for this serial case of advanced oral neoplasms.
Abstract Graphene and graphene-derived materials have been widely applied in various biomedical f... more Abstract Graphene and graphene-derived materials have been widely applied in various biomedical fields. In neuroscience, graphene and its derivatives can be applied as nanocarriers for drug delivery, as compelling biocompatible substrates for tissue engineering, as conductive electrodes for obtaining the stimulation response in studying neural networks, as low photobleaching nanocomposite tags in bioimaging, as enhancers for guiding neural growth and differentiation as regenerative medicine, and so forth. Among these applications, the material composition, functionalization, and dimension of graphene are considerably important. In this chapter, we provide a brief review to address the accomplishments and further perspective of graphene and its related materials applied in neuroscience.
B-cell epitope prediction is important for vaccine design, development of diagnostic reagents and... more B-cell epitope prediction is important for vaccine design, development of diagnostic reagents and for studies to elucidate the interactions between antigen and antibody on a molecular level. Here, we present a new epitope prediction method based on six different scoring functions and exploited LibSVM to predict the antigenic epitopes in protein surface. Using bound structures of the testing dataset, the method was able to predict antigenic epitopes with 50.6% sensitivity, 62.9% specificity, 19% precision and an AUC value of 0.616. While using unbounded structures of the testing dataset, the performance of the method was nearly the same. Compared with another epitope prediction method EPCES, the performance of the method is statistically similar. The results suggest that more effective features that discriminate epitopes from non-epitopes may further improve the performance of the prediction method. Also, the new algorithms for predicting the epitopes are desired and the construction of large with non-redundant datasets is strongly needed.
Botanical Bulletin of Academia Sinica, Jul 1, 2000
... Song-Bin Chang 1,2 , Wen-Huei Chen 1,2,3,4 , Hong-Hwa Chen 2,3 , Yang-Ming Fu 1 , and Yih-Shy... more ... Song-Bin Chang 1,2 , Wen-Huei Chen 1,2,3,4 , Hong-Hwa Chen 2,3 , Yang-Ming Fu 1 , and Yih-Shyan Lin 1. ... For PCR, 6 ng of cpDNA was used as the template DNA, along with 10 mM mixed DIG-dNTP, 0.5 mM of two primers, 0.5 unit of Taq DNA polymerase (DIG DNA ...
ABSTRACT This study employed a carbon microelectromechanical system (C-MEMS) in fabricating a 3D ... more ABSTRACT This study employed a carbon microelectromechanical system (C-MEMS) in fabricating a 3D micro-electrode array of conductive carbon cylinders directly on the surface of a graphite substrate. The capacitance of the array was further enhanced by decorating it with a composite material comprising highly-porous carbon nanofibers (CF) and electroactive RuO2 nanoparticles to function as an active electrode. In galvanostatic charge-discharge tests, the specific capacitance of an electrode decorated with RuO2 30 wt.%/CF was 219.2 F g-1 at a current density of 0.5 A g-1, which is 2.27 times higher than that of the pristine CF electrode. When the current density was increased from 0.5 A g-1 to 3 A g-1, the capacitance retention of the RuO2 30 wt.%/CF electrode was 54.8%. A symmetric supercapacitor based on the RuO2 30 wt.%/CF composite electrode exhibited an impressive energy density of 74.2 Wh kg-1 with power density of 4333 W kg-1. It also demonstrated good capacitance retention of 80.2% following 3000 consecutive charge/discharge cycles at a current density of 2 A g-1.
The intelligrid-oriented on-line relay settings verification system based on EMS real-time data a... more The intelligrid-oriented on-line relay settings verification system based on EMS real-time data are discussed, with related software system designed and fulfilled. Firstly, the research background and current situation of on-line relay settings verification system are summarized. Secondly, the on-line relay settings verification system's general principle, hardware and software design are mainly discussed. And this paper shows the designed hardware structure diagram, the software structure diagram. And the flowchart of main procedure is given. Thirdly, the methods of dealing with EMS real-time data of the on-line verification system are discussed in detail. The verifying principles of sensitivity & selectivity of relay protection are given definitely. It is able to simulate two simultaneous faults, faults in network oscillation, and faults during auto-reclosing. It checks reliability & sensitivity of relay settings under these circumstances. Finally, considering substation-area and wide-area relay protections, this paper points out some key problems of on-line relay settings verification system to be resolved, and its application prospect.
Bernard Lonergan (1904-1984), the accomplished theologian and philosopher, successfully demonstra... more Bernard Lonergan (1904-1984), the accomplished theologian and philosopher, successfully demonstrated an invariant pattern in human understanding which could be appropriated not only in the cognitional structure but also applied to the field of metaphysics. On the other hand, one of the most influential thinkers in modern China, Chu Hsi(朱熹, 1130-1200)developed an original and mature theory named “study of the underlying principles to acquire knowledge” .(ko wu chih chih,,格物致知)It is generally agreed in China that this is one of the most important cognitional theories. I believe both of them share profound similarities especially in the notions of “insight” and so call “sudden Integration” (huo ran guan tong, 豁然貫通)This paper is divided into four main sections. In the first place, I will introduce both of them especially on their academic or cultural background. Secondly, I will argue that Lonergan distinguished isomorphism between knowing and known is comparative with Chu Hsi’s affirmation between the “reason of the human mind” and the “reason of things”. Thirdly, I will analysis both Lonergan’s notion of insight and Chu His’s sudden Integration. Finally, I will distinguish some similarities and discrimination in their philosophies.
Abstract Graphene gains lots of methodical and scientific interests since graphene and its deriva... more Abstract Graphene gains lots of methodical and scientific interests since graphene and its derivatives bring new perspectives and prospects into electrochemical systems. The two-dimensional (2D) material possesses unique physicochemical properties, including high surface area, excellent conductivity, high mechanical strength, ease of functionalization, and mass production. In the past decade, the usage of graphene as a sensor element in miniaturized and biomedical sensor devices is increasing. Including graphene, graphene oxide, and hybrid nanocomposites into electrode modification processes has been shown to improve detection sensitivity and advance electrocatalytic behavior. The overall aim of this chapter is to provide a brief overview of recent advances in applying graphene-based materials into electrochemical sensor for biomedical applications. In particular, graphene-based biosensors for small molecule, protein, nucleic acid, and cell analyses are addressed.
Journal of Mechanics in Medicine and Biology, Dec 1, 2015
Reconstruction of the condyle after an ablative procedure for mouth neoplasms remains a surgical ... more Reconstruction of the condyle after an ablative procedure for mouth neoplasms remains a surgical challenge because these patients with advanced cancer involving the condyle are subjected to massive ablative surgery, and subsequent major reconstruction with free flap and/or reconstruction prosthesis, the prognosis being poor. Therefore, reports of condylar prosthesis in head and neck cancer reconstruction are rare and with mixed results. This report is for the review of the literature and case series study of the condylar prosthesis. As with virtual technique improvement nowadays, an innovation CAD CAM technique is applied for the treatment plan for these patients. We analyze a serial case of advanced oral neoplasms who receives tumor ablation, i.e., mandibulectomy and disarticular resection, and gains symmetrical mandibular architecture after reconstruction with plate and condylar prosthesis. There is still high complication rate (41.7%) noted, namely condylar prosthesis displacement (two cases), impinge on external ear canal (two cases), and erosion of cranial base (one case). The reasons are attributed to massive flap burden, scar contraction, poor dental articulation, and possible technique error during the operation. According to the outcome analysis, virtual technique including with reconstruction plate and condylar prosthesis in conjunction with flap reconstruction are feasible treatment modality for this serial case of advanced oral neoplasms.
Abstract Graphene and graphene-derived materials have been widely applied in various biomedical f... more Abstract Graphene and graphene-derived materials have been widely applied in various biomedical fields. In neuroscience, graphene and its derivatives can be applied as nanocarriers for drug delivery, as compelling biocompatible substrates for tissue engineering, as conductive electrodes for obtaining the stimulation response in studying neural networks, as low photobleaching nanocomposite tags in bioimaging, as enhancers for guiding neural growth and differentiation as regenerative medicine, and so forth. Among these applications, the material composition, functionalization, and dimension of graphene are considerably important. In this chapter, we provide a brief review to address the accomplishments and further perspective of graphene and its related materials applied in neuroscience.
B-cell epitope prediction is important for vaccine design, development of diagnostic reagents and... more B-cell epitope prediction is important for vaccine design, development of diagnostic reagents and for studies to elucidate the interactions between antigen and antibody on a molecular level. Here, we present a new epitope prediction method based on six different scoring functions and exploited LibSVM to predict the antigenic epitopes in protein surface. Using bound structures of the testing dataset, the method was able to predict antigenic epitopes with 50.6% sensitivity, 62.9% specificity, 19% precision and an AUC value of 0.616. While using unbounded structures of the testing dataset, the performance of the method was nearly the same. Compared with another epitope prediction method EPCES, the performance of the method is statistically similar. The results suggest that more effective features that discriminate epitopes from non-epitopes may further improve the performance of the prediction method. Also, the new algorithms for predicting the epitopes are desired and the construction of large with non-redundant datasets is strongly needed.
Botanical Bulletin of Academia Sinica, Jul 1, 2000
... Song-Bin Chang 1,2 , Wen-Huei Chen 1,2,3,4 , Hong-Hwa Chen 2,3 , Yang-Ming Fu 1 , and Yih-Shy... more ... Song-Bin Chang 1,2 , Wen-Huei Chen 1,2,3,4 , Hong-Hwa Chen 2,3 , Yang-Ming Fu 1 , and Yih-Shyan Lin 1. ... For PCR, 6 ng of cpDNA was used as the template DNA, along with 10 mM mixed DIG-dNTP, 0.5 mM of two primers, 0.5 unit of Taq DNA polymerase (DIG DNA ...
ABSTRACT This study employed a carbon microelectromechanical system (C-MEMS) in fabricating a 3D ... more ABSTRACT This study employed a carbon microelectromechanical system (C-MEMS) in fabricating a 3D micro-electrode array of conductive carbon cylinders directly on the surface of a graphite substrate. The capacitance of the array was further enhanced by decorating it with a composite material comprising highly-porous carbon nanofibers (CF) and electroactive RuO2 nanoparticles to function as an active electrode. In galvanostatic charge-discharge tests, the specific capacitance of an electrode decorated with RuO2 30 wt.%/CF was 219.2 F g-1 at a current density of 0.5 A g-1, which is 2.27 times higher than that of the pristine CF electrode. When the current density was increased from 0.5 A g-1 to 3 A g-1, the capacitance retention of the RuO2 30 wt.%/CF electrode was 54.8%. A symmetric supercapacitor based on the RuO2 30 wt.%/CF composite electrode exhibited an impressive energy density of 74.2 Wh kg-1 with power density of 4333 W kg-1. It also demonstrated good capacitance retention of 80.2% following 3000 consecutive charge/discharge cycles at a current density of 2 A g-1.
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