Diffusion-weighted imaging (DWI) tractography has become the tool of choice to probe the human br... more Diffusion-weighted imaging (DWI) tractography has become the tool of choice to probe the human brain's white matter (WM) in vivo. However, tractography algorithms produce a large number erroneous/invalid streamlines [1] largely due to complex ambiguous local fiber configurations (e.g. crossing, kissing or fanning). Moreover, the relationship between the resulting streamlines and the underlying WM microstructure characteristics, such as axon diameter, remains poorly understood [2]. The distinctive aspect of our tractography algorithm from previous methods is the active use of microstructure information about fascicles during the tracking. This enables us to solve areas of complex tissue configuration and separate parallel fascicles with different microstructure characteristics, hence improving the overall tractography process.
Diffusion-weighted imaging (DWI) tractography has become the tool of choice to probe the human br... more Diffusion-weighted imaging (DWI) tractography has become the tool of choice to probe the human brain's white matter (WM) in vivo. However, tractography algorithms produce a large number erroneous/invalid streamlines [1] largely due to complex ambiguous local fiber configurations (e.g. crossing, kissing or fanning). Moreover, the relationship between the resulting streamlines and the underlying WM microstructure characteristics, such as axon diameter, remains poorly understood [2]. The distinctive aspect of our tractography algorithm from previous methods is the active use of microstructure information about fascicles during the tracking. This enables us to solve areas of complex tissue configuration and separate parallel fascicles with different microstructure characteristics, hence improving the overall tractography process.
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Papers by Rachid Deriche