Investigating sex as a biological variable is key to determine obesity manifestation and treatmen... more Investigating sex as a biological variable is key to determine obesity manifestation and treatment response. Individual neuroimaging modalities have uncovered mechanisms related to obesity and altered ingestive behaviors. However, few, if any, studies have integrated data from multimodal brain imaging to predict sex-specific brain signatures related to obesity. We used a data driven approach to investigate how multimodal MRI and clinical features predict a sex-specific signature of participants with high body mass index (BMI; overweight/obese) compared to non-obese BMI in a sex-specific manner. A total of 78 high BMI (55 female) and 105 non-obese BMI (63 female) participants were enrolled in a cross-sectional study. All participants classified as high BMI had a BMI greater than 25 kg/m2 and non-obese BMI had a BMI between 19-20 kg/m2. Multimodal neuroimaging (morphometry, functional resting-state MRI and diffusion weighted scan), along with a battery of behavioral and clinical quest...
Investigating sex as a biological variable is key to determine obesity manifestation and treatmen... more Investigating sex as a biological variable is key to determine obesity manifestation and treatment response. Individual neuroimaging modalities have uncovered mechanisms related to obesity and altered ingestive behaviors. However, few, if any, studies have integrated data from multimodal brain imaging to predict sex-specific brain signatures related to obesity. We used a data driven approach to investigate how multimodal MRI and clinical features predict a sex-specific signature of participants with high body mass index (BMI; overweight/obese) compared to non-obese BMI in a sex-specific manner. A total of 78 high BMI (55 female) and 105 non-obese BMI (63 female) participants were enrolled in a cross-sectional study. All participants classified as high BMI had a BMI greater than 25 kg/m2 and non-obese BMI had a BMI between 19-20 kg/m2. Multimodal neuroimaging (morphometry, functional resting-state MRI and diffusion weighted scan), along with a battery of behavioral and clinical quest...
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Papers by Newton Peng