American Journal of Clinical Oncology: Cancer Clinical Trials, 2000
To determine the efficacy of combined preoperative chemotherapy and radiation therapy for locally... more To determine the efficacy of combined preoperative chemotherapy and radiation therapy for locally advanced rectal carcinoma and the rate of sphincter conservation, a retrospective survey of 39 patients with locally advanced rectal carcinoma treated with various 5-fluorouracil- and leukovorin-based chemotherapy regimens and radiation prior to surgery in a single institution was reviewed. Toxicity, local control and survival were evaluated and compared to previous studies with similarly staged patients. Long-term follow-up was available on 35 patients. The actuarial local failure was 5.7% while the actuarial 5-year survival was 87%. The mortality rate was low (2.5%) and the rate of long-term serious complications acceptable (11.4%). Combined preoperative chemotherapy and radiation provided excellent local regional control despite the poor prognostic factors associated with size, fixation, and the initial advanced tumor stage with acceptable morbidity. In addition, patients with tumors located in the lower third of the rectum may be able to undergo sphincter-sparing surgery. Although the median follow-up is relatively short (32.4 months), the results are in accordance with previous studies of neoadjuvant combined chemotherapy and radiation for locally advanced rectal carcinoma in terms of local and distant control.
How to assess the topology vulnerability of a network has attracted more and more attentions rece... more How to assess the topology vulnerability of a network has attracted more and more attentions recently. Due to the rapid growing number of real-time internet applications developed since the last decade, the discovery of topology weakness related to its quality of service (QoS) is of more interest. In this paper, we provide a novel QoS-aware measurement for assessing the vulnerability of general network topologies. Specifically, we evaluate the vulnerability by detecting the minimum number of link failures that decrease the ...
American Journal of Clinical Oncology: Cancer Clinical Trials, 2000
To determine the efficacy of combined preoperative chemotherapy and radiation therapy for locally... more To determine the efficacy of combined preoperative chemotherapy and radiation therapy for locally advanced rectal carcinoma and the rate of sphincter conservation, a retrospective survey of 39 patients with locally advanced rectal carcinoma treated with various 5-fluorouracil- and leukovorin-based chemotherapy regimens and radiation prior to surgery in a single institution was reviewed. Toxicity, local control and survival were evaluated and compared to previous studies with similarly staged patients. Long-term follow-up was available on 35 patients. The actuarial local failure was 5.7% while the actuarial 5-year survival was 87%. The mortality rate was low (2.5%) and the rate of long-term serious complications acceptable (11.4%). Combined preoperative chemotherapy and radiation provided excellent local regional control despite the poor prognostic factors associated with size, fixation, and the initial advanced tumor stage with acceptable morbidity. In addition, patients with tumors located in the lower third of the rectum may be able to undergo sphincter-sparing surgery. Although the median follow-up is relatively short (32.4 months), the results are in accordance with previous studies of neoadjuvant combined chemotherapy and radiation for locally advanced rectal carcinoma in terms of local and distant control.
How to assess the topology vulnerability of a network has attracted more and more attentions rece... more How to assess the topology vulnerability of a network has attracted more and more attentions recently. Due to the rapid growing number of real-time internet applications developed since the last decade, the discovery of topology weakness related to its quality of service (QoS) is of more interest. In this paper, we provide a novel QoS-aware measurement for assessing the vulnerability of general network topologies. Specifically, we evaluate the vulnerability by detecting the minimum number of link failures that decrease the ...
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