Papers by Mohammadtaghi Sarebanhassanabadi
Galen Medical Journal, Sep 16, 2022
Nursing and midwifery studies, 2017
Background: There is limited data about the effects of smoking cessation (SC) strategies among th... more Background: There is limited data about the effects of smoking cessation (SC) strategies among the candidates for coronary artery bypass graft (CABG) surgery. Objectives: This study aimed to compare the effects of nicotine replacement therapy (NRT) and nursing counseling (NC) on SC among the candidates for CABG. Methods: This randomized controlled trial was made in the heart center of Afshar hospital, Yazd, Iran. Sixty candidates for elective bypass graft were recruited and were randomly allocated either to a NC or a NRT group. Study interventions were implemented from 3 weeks before to 3 weeks after the surgery. Before and after hospitalization for the surgery, patients in the counseling group received telephone counseling while during their 1-week hospital stay, they received face-to-face counseling. Patients in the NRT group received nicotine gums before and after hospitalization and were treated with nicotine patches during their 1-week hospital stay. Data were collected through three questionnaires. The Chi-square and the independent-sample t tests were run to analyze the data. Results: SC rate in the counseling group was significantly higher than the NRT group (63.3% vs. 33.3%; P = 0.038). Moreover, cessation rate among the participants with lower nicotine dependency was significantly greater than those with moderate-to-severe dependency (P = 0.01). Conclusion: NC is more effective than NRT in improving SC rate among the candidates for CABG.
Journal of community health research, Jan 3, 2019
Introduction: Regarding the high impact of Diabetes Mellitus type II (DM II) on human&a... more Introduction: Regarding the high impact of Diabetes Mellitus type II (DM II) on human's health, it seems that identifying DM II risk factors is important to prevent its development. Further studies are needed to ensure the positive role of uric acid in the onset of diabetes. This study targeted at investigating the attributed risk of hyperuricemia for the onset of DM II. Methods: In the present study, 1641 non-diabetic people, selected through multi-stage random cluster sampling, were followed up for 10 years (2006 - 2016). During the study, data on the variables of the study were collected and entered in SPSS 16 which was used to analyze the data. To calculate the attributions of hyperuricemia in the risk of developing diabetes, Levin's formulas and attributed risk related to the prevalence of exposure during these ten years were used. Results: Findings showed DM II was developed in 54.8% of people with hyperuricemia, whereas 28.2% of people with normal uric acid level developed diabetes. The Population Attributed Risk (PAR) of hyperuricemia and uric acid over than 75th percentile of serum uric acid for DM II incidence were calculated by the weighted attributed risk formula was 3.6 % and 26.6 %, respectively. With the treatment of serum uric acid over than 75th percetile, the incidence of diabetes in population was reduced to 24.2% over a 10-year period. Conclusion: In this study, there was a significant correlation between high uric acid level and the risk of diabetes. Therefore, necessary measurements should be taken to treat the hyperuricemia patients in order to prevent the incidence of diabetes caused by high blood acid uric. Keywords: Risk, Diabetes Mellitus, Hyperuricemia, Incidence
Research Square (Research Square), Jun 6, 2023
Background: Various coronary heart disease (CHD) predictive models have been developed for predic... more Background: Various coronary heart disease (CHD) predictive models have been developed for predicting CHD incidence, but none of them has optimal predictive value. Although these models consider diabetes as an important CHD risk factor, they did not consider insulin resistance or Triglyceride. Methods: Two-thousand participants of a community-based Iranian population, aged 20-74 years, were investigated with a mean follow-up of 9.9 years (range: 7.6 to 12.2). The association between TyG-index (a logarithmised combination of fasting blood glucose and triglyceride that demonstrates insulin resistance) and CHD was investigated using multivariate Cox proportional hazard models. Diabetes was substituted for TyG-index in CHD prediction models developed using machine learning. CHD-predicting TyG-index cutoff points were calculated. Results: The incidence of CHD was 14.5%.As compared to the lowest quartile of TyGindex, the fourth quartile had a fully adjusted hazard ratio of 2.32 (CI: 1.16-4.68, p-trend 0.04). In order to predict coronary heart disease, TyG-index >8.42 had the highest negative predictive value. Machine learning models that predicted CHD based on TyG-index performed significantly better than those based on diabetes. TyG-index was not only more important than diabetes in prediction of CHD; it was the most important factor in machine learning models. Conclusion: TyG-index can be used in clinical practice and predictive models as a highly valuable index for predicting and preventing CHD.
Substance abuse, 2022
Background: Lapse has been one of the major challenges in the treatment of drug dependence someti... more Background: Lapse has been one of the major challenges in the treatment of drug dependence sometimes leading to its relapse. Objectives: The aim of this study was to determine the lapse rate in drug dependent patients as for the 2 methods of methadone maintenance treatment (MMT) and buprenorphine maintenance treatment (BMT) in Yazd city. Methods: In this cross-sectional study, 626 female and male patients who had referred to 5 SUD treatment centers in Yazd and had been treated with methadone and buprenorphine maintenance were studied. Participants were divided into 2 groups of MMT and BMT and were evaluated based on lapse within 6 months. Results: In this study, 60.9% of patients were treated with methadone but the rest were treated with buprenorphine. Overall, 33.1% of patients lapsed (35.2% for methadone and 29.8%for buprenorphine). Lapse in methadone treatment was correlated with age, occupational status, and duration of treatment ( P < .05); it failed to correlated with any other demographic and clinical characteristics ( P > .05). Lapse rate in buprenorphine treatment was also related to marital status and the drug used ( P < .05). The mean dose of buprenorphine consumed showed no significant relationship with lapse ( P > .05). The results demonstrated that given the low dose, lapse stood higher in the buprenorphine group than the methadone group; however, as to high dose, the buprenorphine group showed lower lapse than the other group. Conclusions: In regard with the high rate of lapse, it is recommended to consider the factors related to the 2 methods of treatments, and provide counseling and training programs to lower lapse in the patients. Ethics Committee (REC) approval code: IR.SSU.REC.1394.158.
Background: In the world, the main cause of mortality and morbidity is cardiovascular diseases (C... more Background: In the world, the main cause of mortality and morbidity is cardiovascular diseases (CVDs). Genetic and environmental factors are involved in the pathogenesis of diseases. Recently, reports have indicated that the NFKB1 gene rs28362491 is a functional polymorphism. The aim of the study was to investigate between the genotype of the NFKB1 gene and the cardiometabolic risk factor in patients undergoing coronary angiography. Methods and materials: This cross-sectional study was conducted on 462 patients who referred to Afshar Hospital for coronary angiography in 2021-2022. The polymerase chain reaction restriction fragment length polymorphism method was used to detect the genotype of rs28362491. Biochemical parameters were measured using commercial kits. Gensini and Syntax scores were calculated using the angiography result to assess the extent of coronary artery stenosis. Multivariate logistic regression analysis was used to study between cardiometabolic risk factors and ge...
Cardiovascular Biomedicine Journal
Objectives: Children are the most important asset in any country. Since cardiovascular diseases a... more Objectives: Children are the most important asset in any country. Since cardiovascular diseases are built up little by little from childhood, this study attempted to detect the relationship between psychological, spiritual, and social health conditions and cardiovascular risk factors in children. Methods: This study is a cross-sectional study performed on 1035 children aged 6-18 years by multi-stage random cluster sampling in 2016 in Yazd province of Iran. The lifestyle questionnaire (LSQ) was used to collect data. In addition, demographic information (i.e., age and sex) and cardiac risk factors were measured. Logistic regression and t-test were used to analyze the data. Results: In this study, by increasing the mean score of psychological and spiritual health, fasting blood sugar (FBS) decreased significantly (OR = 0.14, 95% CI: 0.02-0.80, P trend = 0.003 and OR = 0.05, 95% CI: 0.01, -0.28, P trend = 0.013). Also, with increasing the mean score of spiritual health, body mass index ...
QT dispersion is an indicator of lack of ventricular repolarization homogeneity and an independen... more QT dispersion is an indicator of lack of ventricular repolarization homogeneity and an independent predictor for ventricular arrhythmia and sudden cardiac death. In this study, we evaluated the effect of inpatient cardiac rehabilitation on QT dispersion in patients admitted to Afshar hospital CCU with diagnosis of acute myocardial infarction (AMI), including ST elevation or non-ST elevation MI. Sixty patients with diagnosis of AMI were randomly divided into two 30-subject groups. The subjects in the first group were undergone inpatient cardiac rehabilitation, and the subjects in the control group received only conventional treatments. QT interval dispersion was measured in two occasions: once in the first day of admission and once before discharge from hospital. In this study there was a significant reduction in QT dispersion in patients undergoing inpatient cardiac rehabilitation (48.4 vs. 42.4 ms, P<0.001), but in the control group, QT dispersion was not significantly reduced (...
Cardiovascular Biomedicine Journal, 2021
Objectives: Acute urinary retention (AUR) can occur as a complication after surgery or cardiac ca... more Objectives: Acute urinary retention (AUR) can occur as a complication after surgery or cardiac catheterization. The aim of this study was to evaluate the effect of wet gauze on relief of AUR in male patients after cardiac catheterization. Methods: In this randomized controlled clinical trial, 36 male patients developing AUR after cardiac catheterization in Afshar Hospital, Yazd, Iran, were allocated to three groups; 13 patients in the group of immersed gauze in tepid water (40 centigrade), 12 patients in the dry gauze group, and 11 patients in the group without any intervention. The gauze was applied on symphysis pubis area. Elimination of AUR was compared between the three groups using chi-square analysis. One-way analysis of variance was used to find significant differences among the three groups regarding the time of relief from AUR. Results: The frequency of the relief of AUR was 61.5%, 25 %, and 9.1% in the groups of wet gauze, dry gauze and without intervention, respectively. ...
Phytotherapy Research, 2020
Myocardial infarction (MI) is one of the leading causes of death in the world. Epidemiological st... more Myocardial infarction (MI) is one of the leading causes of death in the world. Epidemiological studies have shown that dietary flavonoids are inversely related to cardiovascular morbidity and mortality. The study aimed to determine whether quercetin supplementation can improve inflammatory factors, total antioxidant capacity (TAC) and quality of life (QOL) in patients following MI. This randomized double-blind, placebo-controlled trial was conducted on 88 post-MI patients. Participants were randomly assigned into quercetin (n = 44) and placebo groups (n = 44) receiving 500 mg/day quercetin or placebo tablets for 8 weeks. Quercetin supplementation significantly increased serum TAC compared to placebo (Difference: 0.24 (0.01) mmol/L and 0.00 (0.00) mmol/L respectively; p < .001). TNF-α levels significantly decreased in the quercetin group (p = .009); this was not, however, significant compared to the placebo group. As for QOL dimensions, quercetin significantly lowered the scores of insecurity (Difference: −0.66 (12.5) and 0.00 (5.55) respectively; p < .001). No significant changes in IL-6, hs-CRP, blood pressure and other QOL dimensions were observed between the two groups. Quercetin supplementation (500 mg/day) in post-MI patients for 8 weeks significantly elevated TAC and improved the insecurity dimension of QOL, but failed to show any significant effect on inflammatory factors, blood pressure and other QOL dimensions.
Journal of nutrition and food security, Aug 3, 2022
Background: Obesity and overweight are important public health problems which are rapidly growing... more Background: Obesity and overweight are important public health problems which are rapidly growing throughout the world. This study aims to provide 10year incidence estimates of obesity and overweight in adults along with their risk factors in an Iranian adult population. Methods: This cohort study was conducted within the framework of the Yazd Healthy Heart Project (YHHP) throughout phases from 2005-2006 to 2015-2016 among urban adult population. The participants comprised of 1000 males and 1000 females aged 20-74 years from urban areas of Yazd. Cox proportional hazards model was used to examine the potential risk factors for obesity and overweight. Results: A total of 2000 participants aged 47.09 ± 16.97 years and body mass index (BMI) of 21.99 ± 2.21 kg/m 2 were entered in this study at baseline. After 10 years of follow-up, the cumulative incidence of overweight for the entire population was 38.6% (41.6% in women and 36.8% in men). Furthermore, the 10-year cumulative incidence of obesity was 14.8% in the population (20.8% for women and 10.5% for men). Female participants showed a significantly higher incidence rate compared to males either for obesity or overweight. Regarding risk factors, there was a significant association between non-smoking (HR= 1.54, 95% CI: 1.06-2.25), socioeconomic status (HR= 1.82, 95% CI: 1.13-2.94), and education (HR= 1.56, 95% CI: 1.14-2.13) with overweight (P < 0.05). Conclusion: This study revealed the incidence rate of obesity and overweight is significantly high in adult population of Yazd, Iran especially in women. The most important predictors of overweight seem to be smoking, lower socioeconomic status, and education.
One of the most common complications of operation and anesthesia is shivering. The purpose of thi... more One of the most common complications of operation and anesthesia is shivering. The purpose of this study was to compare the effectiveness of Ondanseton and Meperedine in preventing shivering after off-pump coronary artery bypass graft (OPCAB). In this double-blind randomized clinical trial, the sample consisted of 90 patients, who were candidates of CABG under general anesthesia. These patients were assigned to three groups, each containing 30 subjects: meperedine group (A), ondansetron group (B) and control group (C). Group (A) received 0.4 mg/Kg/IV of meperedine, group (B) received 8mg/IV of ondansetron and group (C) received Normal Saline. All these drugs were injected 15 minutes before the end of surgery. After the end of surgery, the intubated patients were transferred to the ICU and their body temperature was assessed through eardrum by a specialist who was blind to the research. The incidence of shivering in groups A, B, and C was 46.48%, 31.18%, and 60.83%, respectively (P=&...
Progress in Pediatric Cardiology, 2021
Abstract Background Anemia and accumulation of iron in the tissues following prolonged transfusio... more Abstract Background Anemia and accumulation of iron in the tissues following prolonged transfusion engenders ventricular dysfunction in the form of heart failure and arrhythmia, which are in fact the most life-threatening complications in patients with thalassemia major. Objectives The aim of this study was to evaluate ECG and echocardiographic changes in patients with thalassemia major. Methods In this cross-sectional research, 72 patients with thalassemia major aged 2–18 years were studied over a period of six months. Patients were assigned into two groups of less than or equal to 10 years and over 10 years; moreover, 72 healthy subjects were included in the study as a control group. Patients were divided into two groups of ferritin less than or equal to 2000 ng/ml and above 2000 ng/ml in terms of the average ferritin of the previous six months. And finally, ECG, 24-hour Holter ECG monitoring, and echocardiography were performed for all patients. Results ECG changes were observed in 43 patients (59.7%) most of whom (35 patients) showed ferritin above 2000 ng/ml. Twenty eight patients (65.1%) with ECG abnormality showed T-wave changes as flattening and negative T-wave. Other changes included PAC (n = 9), PVC (n = 3), paroxysmal AF (n = 1), and RBBB (n = 2). Sinus tachycardia was seen in 18 patients (25%), 13 of whom had ferritin above 2000 ng/ml. In all patients with thalassemia major bearing ferritin above 2000 ng/ml, P duration and P dispersion proved to be longer than the normal population. In addition, in the group over 10 years with ferritin above 2000 ng/ml, QTc and QT dispersion was longer than the normal population. LVEF in both groups up to ferritin below 2000 ng/ml was at the normal range and gradually lowered to less than 55% with increasing ferritin from 2000 ng/ml. Systolic pulmonary arterial pressure gradually elevated with decreasing LVEF from 65% to 45% and heightened from 12 mm Hg to 40 mm Hg. However, with further decrease in EF, while LVEF fell lower than 45%, SPAP again escalated to 52 mm Hg. Conclusions Our study demonstrated that ECG changes in thalassemia major patients are directly associated with serum ferritin level and occur earlier compared to echocardiographic changes.
Advanced biomedical research, 2015
Post cardiac surgery routine chest radiographs (CXRs), ordered without any clinical and laborator... more Post cardiac surgery routine chest radiographs (CXRs), ordered without any clinical and laboratory indications, is a standard obligatory practice in many cardiothoracic centers. Routine CXRs incur cost, manpower, and radiation. The objective of this study is to assess early outcome in off-pump coronary artery bypass (OPCAB) patients with postoperative routine versus clinically indicated CXR protocols. This study is a randomized clinical trial conducted on 231 OPCAB candidates in Afshar Cardiac Center, Yazd, Iran. Patients were categorized into two groups. All 118 patients in group A had routine postoperative CXRs. The 113 patients in group B were selectively exposed to CXR only on clinical indications. All patients were postoperatively followed up for 30 days. Data gathered from both groups were statistically analyzed. Routine postoperative CXRs obtained in 118 OPCAB group A candidates showed abnormal findings in 20 patients that did not require new intervention. One month follow-up...
Advanced Biomedical Research, 2015
the congenital abnormalities life threatening if they not cured. [1] One of the abnormalities is ... more the congenital abnormalities life threatening if they not cured. [1] One of the abnormalities is congenital cardiovascular diseases in which it is the most common congenital irregularity and almost 0.8% of newborn infants suffering from these malfunctions. [2] These infants are faced with many problems, including operational interventions, long-term hospitalization and confidence lack of future life in which all the mentioned problems lead to parents' stress and confidence lack. [1,3] Although operational treatments result in life expectancy and survival up to 85%, [4,5] these treatments impose myriad stress upon infants INTRODUCTION Approximately, 2-3% of newborn infants suffer from
Journal of Biology and Today's World, 2014
Preterm labor is caused by several factors including placental infection and thrombosis. To defin... more Preterm labor is caused by several factors including placental infection and thrombosis. To define the changes in placenta of women with preterm labor, pathological examination of placenta is needed. This case control study aims to find correlation between pathological findings of preterm placentas and chance of preterm labor.Placentas of 100 preterm (either early or late) labors and 100 term deliveries were examined both macroscopically and microscopically. Any evidence of inflammatory lesion, calcification, hematoma and neoplastic mass was evaluated and compared. Early preterm deliveries frequently showed placental calcification, significantly more than in term deliveries (p=0.0001). Inflammatory lesions were present in 20% of placentas of full term newborns, in 60% of early preterm labors, and in 46% of late preterm newborns. Placental cal- cification and placental inflammatory lesions both may be considered as having a positive correlation with preterm labor (p=0.000).several changes are seen in placentas of women with preterm labor, reflecting potential etiologic roles. Each pla- centa in preterm labor should be pathologically examined for the presence of inflammatory lesions, abnormality of vessels, calcifications, hematomas, tumoral masses, etc. Ultrasound examination of placenta during pregnancy may reveal some of these lesions.
Clinical and Experimental Pediatrics, 2020
Background: Pediatric hypertension is the main cause of morbidity and mortality in pediatric popu... more Background: Pediatric hypertension is the main cause of morbidity and mortality in pediatric populations.Purpose: To examine pediatric hypertension in a clinical setting, we used the percentile rank approach and defined hypertension as that above the 95th percentile.Methods: The present study was linked to the a national analytical cross-sectional community-based Iranian Children and Adolescents’ Psychiatric Disorders (IRCAP) survey. The survey was nationwide and funded by the National Institute of Medical Research Development. The IRCAP survey included 31,000 children and adolescents aged 6–18 years in all 31 Iran provinces. The current study included 1,035 children and adolescents and linked the data of the risk factors of cardiovascular disease only in Yazd province via random cluster sampling.Results: Of the total participants, 456 (44.1%) were male and 579 (55.9%) were female. The mean age was 11.2±3.8 years (11.7±3.7 years for males, 11.0±3.6 years for females), while mean hei...
Uploads
Papers by Mohammadtaghi Sarebanhassanabadi