Papers by Mohammad ishtiaq Khan
International Journal of Business and Management
This study examines the impact of federal funds rate on monthly stocks return of the United State... more This study examines the impact of federal funds rate on monthly stocks return of the United States of America. The study made use of secondary data from 31st January 1980 to 31st December 2009 gotten from Fred Economic Data and Economic Research Federal Reserve Bank of St. Louis and the Ordinary Least Square Method was applied to perform the analysis using Eviews 9.0. The findings of this study reveal that before the crisis, the rate of interest significantly predicted monthly stock return while during the crisis; the rate of interest did not significantly predict monthly stock return. In addition, the growth rate of industrial production significantly predicted monthly stock return with while FFR did not significantly predict monthly stock return. Likewise, change in FFR significantly predicted monthly stock return while the growth rate of industrial production did not significantly predict monthly stock return.
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Contact lens & anterior eye : the journal of the British Contact Lens Association, Jan 18, 2018
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Molecular carcinogenesis, Jan 26, 2018
We recently identified and characterized nummularic acid (NA) as a major chemical constituent of ... more We recently identified and characterized nummularic acid (NA) as a major chemical constituent of Fraxinus xanthoxyloides, a medicinal plant used for over hundred years in traditional medicine. In this study, we describe its potential anti-cancer activity using prostate cancer (PCa) cells as a model. We found that NA treatment (5-60 μM) significantly reduced the proliferation and colony formation capabilities of PCa DU145 and C4-2 cells in a time and dose dependent manner, reduced the migratory and invasive properties and increased apoptotic cell population. Mechanistically, we found that NA treatment to PCa cells resulted in a sustained activation of adenosine monophosphate-activated protein kinase (AMPK). NA simultaneously increased acetyl CoA carboxylase phosphorylation and decreased pS6 phosphorylation, the two major substrates of AMPK. Further, NA treatment significantly elevated the cellular ADP/ATP ratio and altered glycolytic rate. We further observed a reversible decrease in...
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Biochemical and Biophysical Research Communications, 2004
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Journal of Materials Research, 2013
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Papers by Mohammad ishtiaq Khan