IEEE transactions on ultrasonics, ferroelectrics, and frequency control, Jan 9, 2016
Shear wave elastography (SWE) is a potentially valuable tool to non-invasively assess ventricular... more Shear wave elastography (SWE) is a potentially valuable tool to non-invasively assess ventricular function in children with cardiac disorders, which could help in the early detection of abnormalities in muscle characteristics. Initial experiments demonstrated the potential of this technique in measuring ventricular stiffness, however, its performance remains to be validated as complicated shear wave (SW) propagation characteristics are expected to arise due to the complex non-homogeneous structure of the myocardium. In this work, we investigated (i) the accuracy of different shear modulus estimation techniques (time-of-flight method and phase velocity analysis) across myocardial thickness and (ii) the effect of the ventricular geometry, surroundings, acoustic loading and material viscoelasticity on SW physics. A generic pediatric (10-15 year old) left ventricular model was studied numerically and experimentally. For the SWE-experiments, a polyvinylalcohol (PVA) replicate of the card...
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