Papers by KRYSTAL JIMENEZ
Contrary to the conventional definition of CKD that is observed in developed countries, studies o... more Contrary to the conventional definition of CKD that is observed in developed countries, studies on CKD in developing countries demonstrate an atypical presentation of the disease, referenced as CKD of unknown origin (CKDu). CKD rates have been exponentially increasing in Nicaragua, particularly in sugarcane workers. This study assesses risk factors associated with this atypical presentation of CKD in patients from an occupational health clinic in rural Nicaragua. This was a cross-sectional study that included 512 patient records (2009 to 2014). Records were randomly selected and transcribed into an electronic database. The data was analyzed with a case-control perspective comparing patients with CKD from those without the disease. A logistic regression analysis was performed in order to examine the personal and occupational risks associated with CKD. Results of this study showed that patients with CKD were predominantly men, approximately ten years younger than patients without CKD,...
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Background: Severe Clostridium difficile-associated disease (CDAD) has been increasingly recogniz... more Background: Severe Clostridium difficile-associated disease (CDAD) has been increasingly recognized, including among persons without traditional risk factors. The specific aims of this study were to determine the prevalence and potential risk factors for CDAD among patients presenting to the emergency department (ED) complaining of acute diarrhea. Methods: Patients ages two years and older presenting with acute diarrhea for up to 14 days duration and without vomiting were prospectively enrolled between November, 2010 and April, 2012 at 9 US EDs. Patients with less than three diarrheal episodes in the prior 24 hours were excluded. Stool and rectal swab specimens were cultured onto medium for isolation of C. difficile. Isolates were tested for toxins A and B through enzyme immunoassay. Treating physicians recorded demographic and risk factor information at bedside. Patients with missing or unknown data were excluded from analyses. Results: Of 331 patients enrolled, 37 (11%) had cultur...
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Papers by KRYSTAL JIMENEZ