Papers by Gulmira Juraboyeva
Central Asian Journal of innovations and research, Jun 15, 2021
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Central Asian Journal of innovations and research, Jun 15, 2021
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Central Asian Journal of innovations and research, Jun 15, 2021
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Central Asian Journal of innovations and research, Jun 15, 2021
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The science fiction historian John Clute describes Wells as "the <br> most important w... more The science fiction historian John Clute describes Wells as "the <br> most important writer the genre has yet seen", and notes his work <br> has been central to both British and American science fiction. <br> Science fiction author and critic Algis Budrys said Wells "remains <br> the outstanding expositor of both the hope, and the despair, <br> which are embodied in the technology and which are the major <br> facts of life in our world". He was nominated for the Nobel Prize <br> in Literature in 1921, 1932, 1935, and 1946.[10] Wells so <br> influenced real exploration of Mars that an impact crater on the <br> planet was named after him.
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TRANS Asian Journal of Marketing & Management Research, 2021
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ASIAN JOURNAL OF MULTIDIMENSIONAL RESEARCH, 2021
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Общество и инновации, 2021
The paper provides case studies of how four school members United Nations agency teach in undergr... more The paper provides case studies of how four school members United Nations agency teach in undergraduate and graduate programs at the colleges of information science promote educational acquisition throughout the course of study. The paper describes the writing assignments in many courses, the objectives of those assignments in enhancing the writing skills of scholars, the pedagogic approaches utilized by the school members and a discussion of the results. Suggestions for assessing student writing will be provided.
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Общество и инновации, 2021
This article outlines communicative system-activity approach in teaching English as a second lang... more This article outlines communicative system-activity approach in teaching English as a second language. This approach is the implementation of such a method of teaching, in which an orderly, systematic and mutually related teaching of the English language as a means of communication is carried out in the conditions of simulated (reproduced) speech activity in the classroom - an integral and integral part of the general (extralinguistic) activity. As a result of this approach in teaching, the system of English language proficiency as a means of communication in the broad sense of the word is formed, implemented and operates.
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Tissue Antigens, 2007
Genetic polymorphisms in neuronal nitric oxide synthase (NOS1) and calmodulin-dependent endotheli... more Genetic polymorphisms in neuronal nitric oxide synthase (NOS1) and calmodulin-dependent endothelial NOS (NOS3) genes are known to influence the course of allergic respiratory disorders. We investigated the role of NOS1 -84 G--&amp;amp;amp;amp;gt;A and NOS3 -786 T--&amp;amp;amp;amp;gt;C, 894 G--&amp;amp;amp;amp;gt;T and 27 base pair (bp) repeat polymorphisms in 125 patients suffering from asthma and/or rhinitis and monosensitized against Dermatophagoides pteronyssinus (Dpter) and 111 controls from Algeria. We found a higher frequency of the -786 C NOS3 allele in patients than in controls [corrected P value (Pc) = 0.04], especially in female cases (Pc = 0.02) and that the &amp;amp;amp;amp;#39;ab&amp;amp;amp;amp;#39; genotype of the 27-bp polymorphism was significantly associated with specific immunoglobulin E production against Dpter (P = 0.006). This study brings further support for the participation of NOS3 gene polymorphism in the pathogenesis of respiratory allergic disorders.
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Clinica Chimica Acta, 2011
The GST enzyme, encoded by hGSTA1 gene, catalyses the GSH dependant detoxification of a variety o... more The GST enzyme, encoded by hGSTA1 gene, catalyses the GSH dependant detoxification of a variety of carcinogenic metabolites and alkylating chemotherapeutic agents. Two genetic variants of hGSTA1, namely hGSTA1*A and hGSTA1*B, are characterized by three linked SNPs, of which -52 G&amp;amp;amp;amp;gt;A variation being solely responsible for the differential promoter activity of hGSTA1. Individuals homozygous for hGSTA1*B have low hepatic expression of hGSTA1. Given the time and labor consuming PCR-RFLP method and the direct prediction of -52 G&amp;amp;amp;amp;gt;A variation, we opted to establish a high throughput DHPLC procedure for the characterization of hGSTA1 variants. 117 DNA samples from South India were included in the study. Control samples were generated for DHPLC using conventional PCR-RFLP technique. Heteroduplexes were produced by in vitro mixing of control DNA samples (hGSTA1*A) to all the samples which are subsequently subjected to DHPLC analysis. The samples were analyzed for the presence of heteroduplexes from the chromatographic profiles. From the total of 117 samples, 43.5% are homozygous for hGSTA1*A allele, 13% are homozygous for hGSTA1*B allele and 43.5% are hGSTA1*A/B heterozygotes. This is, to our knowledge, the first report on the use of DHPLC for the evaluation of hGSTA1 gene promoter polymorphism.
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Papers by Gulmira Juraboyeva