International Journal of Environmental Research and Public Health
This study intended to investigate whether the workload of nurses in the course of providing end-... more This study intended to investigate whether the workload of nurses in the course of providing end-of-life care correlated with their religiousness, spiritual experience and level of agreement with dysthanasia procedures. The respondents included 279 nurses from four Croatian hospitals. A structured and validated instrument was applied. Almost 90% of respondents are religious, and almost 45% of them have daily spiritual experiences. Respondents, especially those with high levels of religiousness and spiritual experience, express a low level of agreement with dysthanasia (mean = 58.21; score = 25–125). Moreover, nurses self-rated (on a scale of 1–5) their workload as quite high, especially when performing contradictory tasks imposed on them by their superiors (mean = 3.05) and during direct contact with dying patients and their family members (mean = 2.56). This significantly highest level of workload was experienced by the youngest nurses (p = 0.01) and nurses with little work experie...
LABORATORIJSKA I KLINIČKA MEDICINA – TEORIJA, INOVACIJE I PRAKSA - Knjiga sažetaka: 7. Hrvatski kongres laboratorijske dijagnostike s međunarodnim sudjelovanjem, 2017
Razvoj tehnologije suočava nas s pitanjem bespomoćnosti osobe koja se nalazi u fazi smrtnog ishod... more Razvoj tehnologije suočava nas s pitanjem bespomoćnosti osobe koja se nalazi u fazi smrtnog ishoda bolesti. Proces umiranja u svojoj jedinstvenosti i univerzalnosti nadilazi dimenziju čovjekove svijesti i podsvijesti te zahtijeva multidisciplinarni pristup članova tima koji skrbe o pacijentu i surađuje s članovima njegove obitelji. Temelj palijativnog pristupa je odnos utemeljen na razumijevanju, osjetljivosti, empatiji, fleksibilnosti, otvorenoj dvosmjernoj komunikaciji liječnik-bolesnik i raznovrsnoj komunikaciji u socijalnoj mreži. Komunikacija u palijativnoj skrbi zahtijeva znanje, kompetencije i vještine u specifičnosti obavljanja svakodnevnog posla, koji je težak proces. Jedna od najvažnijih vještina potrebnih u komunikaciji u palijativnoj skrbi je znati čuti i slušati. To je vrsta slušanja u kojem se pacijentu pokazuje da se doista sluša ono što on govori, pita i osjeća. U trenutku kada medicinski postupci i intervencije kod bolesnika od neizlječivih bolesti ne pokazuju pozit...
Difficulties in sexual functioning are very frequent in patients with chronic kidney disease (CKD... more Difficulties in sexual functioning are very frequent in patients with chronic kidney disease (CKD). Sexual dysfunction (SD) can significantly diminish the quality of life (QOL) of affected individuals. The aim of this study was to determine the prevalence of SD in female patients undergoing chronic hemodialysis (CHD) and after renal transplantation (RTx) and to compare these groups with each other and with healthy control. The survey was conducted among 123 female participants in a relationship, 28 of them undergoing CHD, 39 after RTx, and 56 healthy women without CKD. For the assessment of the sexual function and comorbidities, the Female Sexual Function Index (FSFI) questionnaire and Ifudu Comorbidity Index were used, respectively. Median age of all female participants was 60 (50–68). The median age of female CHD patients was 66 (61.3–72.8), RTx patients 56 (48–61), and the control group 59.5 (47.5–67.75). Among all participants, CHD female patients had the lowest scores in all sexual functioning domains. Compared to their age-adjusted control group, CHD patients had lower scores in desire, orgasm, and FSFI full score, whereas RTx patients had lower total FSFI scores and scores in all domains except for desire compared to their controls. Women with lower education, in marriage, and with more comorbidities had lower scores in sexual function domains. Our study shows that SD in female patients undergoing CHD treatment or those after RTx is substantially higher than that in healthy women. We suggest that female patient treated for CKD should have proper care regarding their sexual health, and differences in demographic and medical factors should be taken into consideration during the treatment management.
Obesity is a multifactorial chronic disease characterized by the excessive accumulation of fat in... more Obesity is a multifactorial chronic disease characterized by the excessive accumulation of fat in adipose tissue driven by hypertrophy and hyperplasia of adipocytes through adipogenesis. Adipogenesis plays a key role in the development of obesity and related metabolic disorders, which makes it potential target for the therapeutic approach to obesity. An increasing number of studies confirm the pleiotropic action of the combined treatment with metformin and statins, suggesting their anti-hypertensive, anti-inflammatory, and anti-adipogenic effect. The aim of this study was to analyze the effect of different doses of metformin (MET) and simvastatin (SIM) on the expression of key transcription factors of adipogenesis. Mouse 3T3-L1 preadipocytes were induced to differentiation in adipogenic medium with sustained MET and SIM treatment to assess the effect on adipogenesis. Nine days after initiating adipogenesis, the cells were prepared for further experiments, including Oil Red O stainin...
Aim To validate the Croatian translation of the Body Image Scale in breast cancer and chronic kid... more Aim To validate the Croatian translation of the Body Image Scale in breast cancer and chronic kidney disease patients. Methods The scale was administered to 172 breast cancer patients and to 89 chronic kidney disease patients. Measures of depression and anxiety were used to assess the convergent validity. Both groups were divided based on their treatment types. Results In both samples, the scale showed high internal consistency (Cronbach's Alpha 0.958 for breast cancer patients, 0.855 for chronic kidney disease patients) item-total correlations (0.72-0.88 for breast cancer patients, 0.46-0.65 for chronic kidney disease patients), and convergent validity. In the breast cancer group, the factor analysis showed a single-factor solution, while in the chronic kidney disease group it showed a two-factor solution. Good discriminant validity was obtained among breast cancer patients, with patients who underwent complete mastectomy scoring higher than patients who underwent partial maste...
International Journal of Environmental Research and Public Health
This study intended to investigate whether the workload of nurses in the course of providing end-... more This study intended to investigate whether the workload of nurses in the course of providing end-of-life care correlated with their religiousness, spiritual experience and level of agreement with dysthanasia procedures. The respondents included 279 nurses from four Croatian hospitals. A structured and validated instrument was applied. Almost 90% of respondents are religious, and almost 45% of them have daily spiritual experiences. Respondents, especially those with high levels of religiousness and spiritual experience, express a low level of agreement with dysthanasia (mean = 58.21; score = 25–125). Moreover, nurses self-rated (on a scale of 1–5) their workload as quite high, especially when performing contradictory tasks imposed on them by their superiors (mean = 3.05) and during direct contact with dying patients and their family members (mean = 2.56). This significantly highest level of workload was experienced by the youngest nurses (p = 0.01) and nurses with little work experie...
LABORATORIJSKA I KLINIČKA MEDICINA – TEORIJA, INOVACIJE I PRAKSA - Knjiga sažetaka: 7. Hrvatski kongres laboratorijske dijagnostike s međunarodnim sudjelovanjem, 2017
Razvoj tehnologije suočava nas s pitanjem bespomoćnosti osobe koja se nalazi u fazi smrtnog ishod... more Razvoj tehnologije suočava nas s pitanjem bespomoćnosti osobe koja se nalazi u fazi smrtnog ishoda bolesti. Proces umiranja u svojoj jedinstvenosti i univerzalnosti nadilazi dimenziju čovjekove svijesti i podsvijesti te zahtijeva multidisciplinarni pristup članova tima koji skrbe o pacijentu i surađuje s članovima njegove obitelji. Temelj palijativnog pristupa je odnos utemeljen na razumijevanju, osjetljivosti, empatiji, fleksibilnosti, otvorenoj dvosmjernoj komunikaciji liječnik-bolesnik i raznovrsnoj komunikaciji u socijalnoj mreži. Komunikacija u palijativnoj skrbi zahtijeva znanje, kompetencije i vještine u specifičnosti obavljanja svakodnevnog posla, koji je težak proces. Jedna od najvažnijih vještina potrebnih u komunikaciji u palijativnoj skrbi je znati čuti i slušati. To je vrsta slušanja u kojem se pacijentu pokazuje da se doista sluša ono što on govori, pita i osjeća. U trenutku kada medicinski postupci i intervencije kod bolesnika od neizlječivih bolesti ne pokazuju pozit...
Difficulties in sexual functioning are very frequent in patients with chronic kidney disease (CKD... more Difficulties in sexual functioning are very frequent in patients with chronic kidney disease (CKD). Sexual dysfunction (SD) can significantly diminish the quality of life (QOL) of affected individuals. The aim of this study was to determine the prevalence of SD in female patients undergoing chronic hemodialysis (CHD) and after renal transplantation (RTx) and to compare these groups with each other and with healthy control. The survey was conducted among 123 female participants in a relationship, 28 of them undergoing CHD, 39 after RTx, and 56 healthy women without CKD. For the assessment of the sexual function and comorbidities, the Female Sexual Function Index (FSFI) questionnaire and Ifudu Comorbidity Index were used, respectively. Median age of all female participants was 60 (50–68). The median age of female CHD patients was 66 (61.3–72.8), RTx patients 56 (48–61), and the control group 59.5 (47.5–67.75). Among all participants, CHD female patients had the lowest scores in all sexual functioning domains. Compared to their age-adjusted control group, CHD patients had lower scores in desire, orgasm, and FSFI full score, whereas RTx patients had lower total FSFI scores and scores in all domains except for desire compared to their controls. Women with lower education, in marriage, and with more comorbidities had lower scores in sexual function domains. Our study shows that SD in female patients undergoing CHD treatment or those after RTx is substantially higher than that in healthy women. We suggest that female patient treated for CKD should have proper care regarding their sexual health, and differences in demographic and medical factors should be taken into consideration during the treatment management.
Obesity is a multifactorial chronic disease characterized by the excessive accumulation of fat in... more Obesity is a multifactorial chronic disease characterized by the excessive accumulation of fat in adipose tissue driven by hypertrophy and hyperplasia of adipocytes through adipogenesis. Adipogenesis plays a key role in the development of obesity and related metabolic disorders, which makes it potential target for the therapeutic approach to obesity. An increasing number of studies confirm the pleiotropic action of the combined treatment with metformin and statins, suggesting their anti-hypertensive, anti-inflammatory, and anti-adipogenic effect. The aim of this study was to analyze the effect of different doses of metformin (MET) and simvastatin (SIM) on the expression of key transcription factors of adipogenesis. Mouse 3T3-L1 preadipocytes were induced to differentiation in adipogenic medium with sustained MET and SIM treatment to assess the effect on adipogenesis. Nine days after initiating adipogenesis, the cells were prepared for further experiments, including Oil Red O stainin...
Aim To validate the Croatian translation of the Body Image Scale in breast cancer and chronic kid... more Aim To validate the Croatian translation of the Body Image Scale in breast cancer and chronic kidney disease patients. Methods The scale was administered to 172 breast cancer patients and to 89 chronic kidney disease patients. Measures of depression and anxiety were used to assess the convergent validity. Both groups were divided based on their treatment types. Results In both samples, the scale showed high internal consistency (Cronbach's Alpha 0.958 for breast cancer patients, 0.855 for chronic kidney disease patients) item-total correlations (0.72-0.88 for breast cancer patients, 0.46-0.65 for chronic kidney disease patients), and convergent validity. In the breast cancer group, the factor analysis showed a single-factor solution, while in the chronic kidney disease group it showed a two-factor solution. Good discriminant validity was obtained among breast cancer patients, with patients who underwent complete mastectomy scoring higher than patients who underwent partial maste...
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