Papers by Franck Forterre
Krankheiten der Katze
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Veterinary Surgery, 2022
OBJECTIVE To determine cutoff values for the diagnosis of atlantoaxial instability (AAI) based on... more OBJECTIVE To determine cutoff values for the diagnosis of atlantoaxial instability (AAI) based on cross-sectional imaging in small-breed dogs. STUDY DESIGN Retrospective multicenter study. SAMPLE POPULATION Client-owned dogs (n = 123) and 28 cadavers. METHODS Dogs were assigned to three groups: a control group, a "potentially unstable" group, and an AAI-affected group, according to imaging findings and clinical signs. The ventral compression index (VCI), cranial translation ratio (CTR), C1-C2 overlap, C1-C2 angle, atlantoaxial distance, basion-dens interval, dens-to-axis length ratio (DALR), power ratio, and clivus canal angles were measured on CT or T2-weighted magnetic resonance (MR) images. Receiver operating characteristic (ROC) analysis was performed to define cutoff values in flexed (≥25°) and extended (<25°) head positions. RESULTS Cutoff values for the VCI of ≥0.16 in extended and ≥0.2 in flexed head positions were diagnostic for AAI (sensitivity of 100% and 100%, specificity of 94.54% and 96.67%, respectively). Cutoff values for the other measurements were defined with a lower sensitivity (75%-96%) and specificity (70%-97%). A combination of the measurements did not increase the sensitivity and specificity compared with the VCI as single measurement. CONCLUSION Cutoff values for several imaging measurements were established with good sensitivity and specificity. The VCI, defined as the ratio between the ventral and dorsal atlantodental interval, had the highest sensitivity and specificity in both head positions. CLINICAL SIGNIFICANCE The use of defined cutoff values allows an objective diagnosis of AAI in small-breed dogs. The decision for surgical intervention, however, should remain based on a combination of clinical and imaging findings.
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Five dogs with peripheral nerve injuries (3 radial nerve and 2 peroneal nerve paralysis) were pre... more Five dogs with peripheral nerve injuries (3 radial nerve and 2 peroneal nerve paralysis) were presented at the Small Animal Clinic of the Freie University in Berlin, Germany and were treated with a new surgical technique. The patients were examinated clinically, neurologically and an electromyographic examination was performed. The surgical technique consisted in a direct transposition of a sound nerve in a paralysed muscle. After 12 weeks, 4 dogs were able to use their leg in a correct fashion. One dog showed an improvement of the clinical signs but remained unable to bear weight on his leg.
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Krankheiten der Katze, 2019
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Frontiers in Veterinary Science, 2018
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Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere, 2019
ZusammenfassungEine große Vielfalt an Ätiologien gilt als ursächlich für das Nervenwurzelsyndrom ... more ZusammenfassungEine große Vielfalt an Ätiologien gilt als ursächlich für das Nervenwurzelsyndrom beim Hund. Dabei zählen der lateralisierte Bandscheibenvorfall, die Foraminalstenose sowie maligne und benigne Nervenscheidentumoren zu den wichtigsten beschriebenen Auslösern. Das klinische Bild des Nervenwurzelsyndroms zeichnet sich aus durch eine Monoparese in Verbindung mit einer fortschreitenden Lahmheit, die mit einer Schonhaltung der betroffenen Gliedmaße im Stand einhergehen kann. Obwohl die Problematik bei Klinikern gut bekannt ist, gibt es in der tiermedizinischen Literatur keinen Übersichtsartikel, der das Thema „Nervenwurzelsyndrom beim Kleintier“ spezifisch behandelt. Meist wird es lediglich als Symptom seiner potenziellen Ätiologien erwähnt, dem sog. Nervenwurzelzeichen (nerve root sign). Bei der Pathophysiologie der Nervenwurzelkompression oder -irritation spielen eine Reihe biomechanischer und biochemischer Faktoren eine Rolle, die einzeln oder im Zusammenspiel auftreten ...
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Veterinary and Comparative Orthopaedics and Traumatology, 2004
SummaryTwenty-eight feline pelves (56 hemipelves) were examined in order to identify the location... more SummaryTwenty-eight feline pelves (56 hemipelves) were examined in order to identify the location for optimal sacroiliac screw placement in sacroiliac fracture-luxation repair. A drill hole was started on the median plane of the hemipelvis in the centre of the body of the first sacral segment until it penetrated the lateral cortex of the ilial wing, thus providing optimal drill hole placement. The position of the drill hole on the articular surface of the sacral wing and on the lateral surface of the ilial wing was measured. The distance of the drill hole from the cranial margin of the sacral wing was 51% of sacral wing length, just cranial to the crescent shaped hyaline cartilage. The distance from the dorsal margin was 47% of sacral wing height. The drill bit direction has to be adjusted to the cranio-caudal inclination (range 10° to 29°) and dorso-ventral inclination (range 2° to 25°) of the sacral wing. A notch in the cranial edge of the sacral wing was present, with variable po...
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Journal of veterinary internal medicine, 2016
The pathophysiology of ascending/descending myelomalacia (ADMM) after canine intervertebral disk ... more The pathophysiology of ascending/descending myelomalacia (ADMM) after canine intervertebral disk (IVD) extrusion remains poorly understood. Vasoactive molecules might contribute. To investigate the immunoreactivity of endothelin-1 (ET-1) in the uninjured and injured spinal cord of dogs and its potential association with intramedullary hemorrhage and extension of myelomalacia. Eleven normal control and 34 dogs with thoracolumbar IVD extrusion. Spinal cord tissue of dogs retrospectively selected from our histopathologic database was examined histologically at the level of the extrusion (center) and in segments remote from the center. Endothelin-1 immunoreactivity was examined immunohistochemically and by in situ hybridization. Associations between the immunoreactivity for ET-1 and the severity of intramedullary hemorrhage or the extension of myelomalacia were examined. Endothelin-1 was expressed by astrocytes, macrophages, and neurons and only rarely by endothelial cells in all dogs. ...
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Krankheiten der Katze, 2019
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Acta Veterinaria Scandinavica, 2021
Background Intervertebral disc extrusions in the thoracolumbar region are a common spinal neurolo... more Background Intervertebral disc extrusions in the thoracolumbar region are a common spinal neurologic disorder in dogs and usually considered a neurological emergency. Several factors, like timing of surgery, have previously been analysed in order to determine the effect on outcome and time of recovery. Most studies have investigated one defined population of dogs and the influence of a single factor on the overall outcome. In this retrospective study, a large cohort of dogs and the influence of one or combinations of several factors on outcome and time of recovery were analysed. Results The bivariate analysis demonstrated a significant association between the following variables and the time of recovery: the time span between the onset of clinical signs and surgery (Cramers Phi $$\varphi^{\prime}$$ φ ′ = 0.14; P = 0.003), the grade of severity ( $$\varphi^{\prime}$$ φ ′ = 0.23; P < 0.001) and the implementation of physical rehabilitation ( $$\varphi^{\prime}$$ φ ′ = 0.2; P <...
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Papers by Franck Forterre