In this article, we prepared a series of chitosan that has various molecular weights (MW) and deg... more In this article, we prepared a series of chitosan that has various molecular weights (MW) and degree of deacetylation (DDA) and two types of carboxymethylated chitosan. Also, we examined whether their antibacterial activity against Escherichia coli (E. coli) depended on the MW, ...
Gallium Nitride has emerged as the technology of choice for the next generation high power electr... more Gallium Nitride has emerged as the technology of choice for the next generation high power electronics. However, its ability to handling high power also makes it the perfect technology candidate for highly survivable receiver components. This has obvious cost benefit for the footprint of the LNA will be smaller since no extra front-end protection circuitry is required. In this paper, a wideband Gallium Nitride HEMT low noise amplifier MMIC, using novel dual gate topology, has been design and manufactured to demonstrate Gallium Nitride low noise capability.
Overexpression of the epidermal growth factor receptor (EGFR) has been observed in a wide variety... more Overexpression of the epidermal growth factor receptor (EGFR) has been observed in a wide variety of human cancers and is associated with a poor clinical prognosis. In many cases, growth of the tumor cells is dependent on EGFR-mediated signals, because inhibition of binding of factors to the EGFR leads to cell death. Using XenoMouse technology, a fully human EGFR-specific monoclonal antibody, ABX-EGF, with high affinity (5 x 10(-11) mol/L) has been generated. ABX-EGF blocks binding of both epidermal growth factor and transforming growth factor alpha to the EGFR, inhibits tyrosine phosphorylation of the EGFR, and inhibits cellular proliferation. In vivo, ABX-EGF not only blocks formation of human epidermoid carcinoma A431 xenografts in athymic mice, but also mediates therapeutic elimination of established tumors and acts cooperatively with chemotherapeutics in mediating tumor regression. These observations provide a strong basis for the development of ABX-EGF as a therapeutic agent for human solid tumors that overexpress EGFR.
In this article, we prepared a series of chitosan that has various molecular weights (MW) and deg... more In this article, we prepared a series of chitosan that has various molecular weights (MW) and degree of deacetylation (DDA) and two types of carboxymethylated chitosan. Also, we examined whether their antibacterial activity against Escherichia coli (E. coli) depended on the MW, ...
Gallium Nitride has emerged as the technology of choice for the next generation high power electr... more Gallium Nitride has emerged as the technology of choice for the next generation high power electronics. However, its ability to handling high power also makes it the perfect technology candidate for highly survivable receiver components. This has obvious cost benefit for the footprint of the LNA will be smaller since no extra front-end protection circuitry is required. In this paper, a wideband Gallium Nitride HEMT low noise amplifier MMIC, using novel dual gate topology, has been design and manufactured to demonstrate Gallium Nitride low noise capability.
Overexpression of the epidermal growth factor receptor (EGFR) has been observed in a wide variety... more Overexpression of the epidermal growth factor receptor (EGFR) has been observed in a wide variety of human cancers and is associated with a poor clinical prognosis. In many cases, growth of the tumor cells is dependent on EGFR-mediated signals, because inhibition of binding of factors to the EGFR leads to cell death. Using XenoMouse technology, a fully human EGFR-specific monoclonal antibody, ABX-EGF, with high affinity (5 x 10(-11) mol/L) has been generated. ABX-EGF blocks binding of both epidermal growth factor and transforming growth factor alpha to the EGFR, inhibits tyrosine phosphorylation of the EGFR, and inhibits cellular proliferation. In vivo, ABX-EGF not only blocks formation of human epidermoid carcinoma A431 xenografts in athymic mice, but also mediates therapeutic elimination of established tumors and acts cooperatively with chemotherapeutics in mediating tumor regression. These observations provide a strong basis for the development of ABX-EGF as a therapeutic agent for human solid tumors that overexpress EGFR.
Uploads
Papers by Dong Yang