BACKGROUND: Madhumeha (diabetes mellitus [DM]) disease is one of the very few diseases, which has... more BACKGROUND: Madhumeha (diabetes mellitus [DM]) disease is one of the very few diseases, which has been found in the history and culture of India and across the globe. Since ages, even in the twenty-first century, this disease is a cause of concern to the world due to its morbidity and long-term complications. Traditional medicines are still found to be very useful in the improvement of quality of life (QOL) of the patients with Madhumeha. Ayurvedic formulations are found to be useful in the management of type II DM and in promoting health. OBJECTIVE: Saptavimshatika Guggulu (SG) and Haridra Churna (HC) were evaluated to assess their clinical effectiveness in the management of type 2 diabetes. A secondary objective was to assess the changes in the QOL of the patients with type 2 DM and the clinical safety of SG and HC. MATERIALS AND METHODS: This multicenter clinical study was critically evaluated to assay the clinical efficacy and safety profile of ayurvedic formulations, SG 500 g t...
Materia Medica of Ayurveda is using best scientific and applied Rasa Chikitsa and Rasa Ausadhi oc... more Materia Medica of Ayurveda is using best scientific and applied Rasa Chikitsa and Rasa Ausadhi occupied an important place in the field of Ayurvedic practice. It deals with metal, minerals and poisonous drug. Starting from 9th century AD to 16th century AD was the sunshine period of Rasa Chikitsa, then gradually decline probably due to introduction of western medicine. It’s efficacy is superior than plant formulation due to its unlimited expiry, effective in small dose, abundant resource and quickly effective on the target tissue even it can handle emergency situations also but the most important background of Rasa Ausadhi received highly technical processing (Shodhan, Marana, Jarana[1]) for the treatment of diseases. In this content liver function test and estimation of renal profile (before and after) will help for gaining confidence both in patient and physician prior to use compound formulations containing Tamra Bhasma. Tamra Bhasma is a metal compound which is used for treatmen...
Research journal of pharmacy and technology, Mar 24, 2022
Skin burn is a common health problem that needs a fast and accurate treatment; else, it can have ... more Skin burn is a common health problem that needs a fast and accurate treatment; else, it can have a worse prognosis. The available treatment options pose limitations due to their adverse effects; thus there is an urgent need to find newer treatment options for burn wound healing that can provide a safer and faster treatment option. Ayurveda gives a plethora of medicinal plants and their formulations which have been used in the management of burn wound. The Ayurvedic ointment formulated in this experiment utilizes essential ayurvedic ingredients which are known for their burn wound healing potential. The current work includes the formulation of the Ayurvedic ointment, its standardization, toxicity and efficacy study. The Ayurvedic ointment was formulated by fusion method, and its physicochemical characterization ensures the purity of the compounds used for the formulation. The ointment formulated is well set under the safety parameters for the presence of heavy metals and also free from microbial and fungal contamination. It has obtained optimum spreadability and viscosity, making it desirable for application on wounds. In the acute dermal toxicity study, it has shown no adverse effect on the animals as there were no significant changes in the body weight and feed intake and water consumption, thus confirming it as a safe formulation. It has shown significant rate of wound healing and period of re-epithelization in the Wistar rat model. It can be a potential ointment for burn wound treatment, and in future, it can be considered for clinical studies to validate its safety and efficacy in humans.
Plectranthus amboinicus (Lour.) Spreng. (family Lamiaceae) is commonly known as parnayavani by th... more Plectranthus amboinicus (Lour.) Spreng. (family Lamiaceae) is commonly known as parnayavani by the several ethnic groups of West Bengal. The plant used by the traditional healers in cough, common cold, abdominal flatulence, indigestion, constipation etc. The preliminary phytochemical analysis, HPTLC finger printing and detailed pharmacognostical studies of its leaves revealed presence of distinctive characteristics, which help in identifying the specimen.
In Ayurveda, Acharya Madhava Kar mentioned first the Amavata as a special disease entity. Accordi... more In Ayurveda, Acharya Madhava Kar mentioned first the Amavata as a special disease entity. According to the clinical features and pathogenesis Amavata very closely resembles Rheumatoid arthritis. In Amavata, Ama (bio- toxin) and Vata (biophysical force or kinetics) are playing the most important role in the samprapti (pathogenesis) of this disease. The Chikitsa (management) of Amavata (Rheumatoid arthritis) is more clearly and precisely de- scribed in Chakradutta. Acharya Chakradatta was the pioneer in describing the principles of treatment for this disease, which are Langhana (body lightness procedure), Swedana (warm compress), drugs having Tikta-Katu Rasa (bitter-pungent taste) and Deepana (gastric stimulant) action, Virechana (purgation therapy), Snehapana (intake of grita or oil) and Anuvasana (enema with Ayurvedic oil) as well as Ksharabasti (enema with Ayurvedic alkali preparation). Keywords: Amavata, Rheumatoid arthritis, Chikitsa, management, Chakradutta
One important plant based Ayurvedic drug i.e. (i.e. Bhaishajya Ratnavali) for its probable ern ch... more One important plant based Ayurvedic drug i.e. (i.e. Bhaishajya Ratnavali) for its probable ern chemical review in context of Amavata tains six ingredients and out of which five are plant based and one is mineral based ingredient. The Virya, Vipak and Karma of ingredients of Amavata (Rheumatoid arthritis). The Physicochemical study on this drug constituents, less moisture and less water soluble constituents. The Phytochemical study ducing sugars, saponin glycosides, phenolic compounds and gum phytocostitutents are indicated under short ultra vi der long ultra violet ray (366 nm) into the sample of this drug by thin layer chromatography (TLC) study.
Research Journal of Pharmacology and Pharmacodynamics, 2021
In herbal medicine, there is a substantial amount of variety of plants have been used to treat ne... more In herbal medicine, there is a substantial amount of variety of plants have been used to treat neurodegenerative disorders including Alzheimer's (AD)as well as other memory-related issues. Dementia is a neurological condition characterised by a progressive loss in emotional and cognitive abilities. Dementia is linked to a number of conditions like inadequate cerebral blood flow, poison toxicity, and other risk factors and conditions mitochondrial dysfunction, oxidative injury, and, in certain cases coexistence with other diseases like Alzheimer's disease (AD), Huntington's disease, Parkinson's syndrome (PD) and Attention Deficit Hyperactivity Disorder (ADHD).Despite the fact that there are well-established semi-synthetic medications for the treatment of AD and AD-related dementia, the majority of them have a number of side effects. As a result, conventional medicine offers a variety of plant-derived lead molecules that may be valuable in future medical studies. In th...
BACKGROUND: Madhumeha (diabetes mellitus [DM]) disease is one of the very few diseases, which has... more BACKGROUND: Madhumeha (diabetes mellitus [DM]) disease is one of the very few diseases, which has been found in the history and culture of India and across the globe. Since ages, even in the twenty-first century, this disease is a cause of concern to the world due to its morbidity and long-term complications. Traditional medicines are still found to be very useful in the improvement of quality of life (QOL) of the patients with Madhumeha. Ayurvedic formulations are found to be useful in the management of type II DM and in promoting health. OBJECTIVE: Saptavimshatika Guggulu (SG) and Haridra Churna (HC) were evaluated to assess their clinical effectiveness in the management of type 2 diabetes. A secondary objective was to assess the changes in the QOL of the patients with type 2 DM and the clinical safety of SG and HC. MATERIALS AND METHODS: This multicenter clinical study was critically evaluated to assay the clinical efficacy and safety profile of ayurvedic formulations, SG 500 g t...
Materia Medica of Ayurveda is using best scientific and applied Rasa Chikitsa and Rasa Ausadhi oc... more Materia Medica of Ayurveda is using best scientific and applied Rasa Chikitsa and Rasa Ausadhi occupied an important place in the field of Ayurvedic practice. It deals with metal, minerals and poisonous drug. Starting from 9th century AD to 16th century AD was the sunshine period of Rasa Chikitsa, then gradually decline probably due to introduction of western medicine. It’s efficacy is superior than plant formulation due to its unlimited expiry, effective in small dose, abundant resource and quickly effective on the target tissue even it can handle emergency situations also but the most important background of Rasa Ausadhi received highly technical processing (Shodhan, Marana, Jarana[1]) for the treatment of diseases. In this content liver function test and estimation of renal profile (before and after) will help for gaining confidence both in patient and physician prior to use compound formulations containing Tamra Bhasma. Tamra Bhasma is a metal compound which is used for treatmen...
Research journal of pharmacy and technology, Mar 24, 2022
Skin burn is a common health problem that needs a fast and accurate treatment; else, it can have ... more Skin burn is a common health problem that needs a fast and accurate treatment; else, it can have a worse prognosis. The available treatment options pose limitations due to their adverse effects; thus there is an urgent need to find newer treatment options for burn wound healing that can provide a safer and faster treatment option. Ayurveda gives a plethora of medicinal plants and their formulations which have been used in the management of burn wound. The Ayurvedic ointment formulated in this experiment utilizes essential ayurvedic ingredients which are known for their burn wound healing potential. The current work includes the formulation of the Ayurvedic ointment, its standardization, toxicity and efficacy study. The Ayurvedic ointment was formulated by fusion method, and its physicochemical characterization ensures the purity of the compounds used for the formulation. The ointment formulated is well set under the safety parameters for the presence of heavy metals and also free from microbial and fungal contamination. It has obtained optimum spreadability and viscosity, making it desirable for application on wounds. In the acute dermal toxicity study, it has shown no adverse effect on the animals as there were no significant changes in the body weight and feed intake and water consumption, thus confirming it as a safe formulation. It has shown significant rate of wound healing and period of re-epithelization in the Wistar rat model. It can be a potential ointment for burn wound treatment, and in future, it can be considered for clinical studies to validate its safety and efficacy in humans.
Plectranthus amboinicus (Lour.) Spreng. (family Lamiaceae) is commonly known as parnayavani by th... more Plectranthus amboinicus (Lour.) Spreng. (family Lamiaceae) is commonly known as parnayavani by the several ethnic groups of West Bengal. The plant used by the traditional healers in cough, common cold, abdominal flatulence, indigestion, constipation etc. The preliminary phytochemical analysis, HPTLC finger printing and detailed pharmacognostical studies of its leaves revealed presence of distinctive characteristics, which help in identifying the specimen.
In Ayurveda, Acharya Madhava Kar mentioned first the Amavata as a special disease entity. Accordi... more In Ayurveda, Acharya Madhava Kar mentioned first the Amavata as a special disease entity. According to the clinical features and pathogenesis Amavata very closely resembles Rheumatoid arthritis. In Amavata, Ama (bio- toxin) and Vata (biophysical force or kinetics) are playing the most important role in the samprapti (pathogenesis) of this disease. The Chikitsa (management) of Amavata (Rheumatoid arthritis) is more clearly and precisely de- scribed in Chakradutta. Acharya Chakradatta was the pioneer in describing the principles of treatment for this disease, which are Langhana (body lightness procedure), Swedana (warm compress), drugs having Tikta-Katu Rasa (bitter-pungent taste) and Deepana (gastric stimulant) action, Virechana (purgation therapy), Snehapana (intake of grita or oil) and Anuvasana (enema with Ayurvedic oil) as well as Ksharabasti (enema with Ayurvedic alkali preparation). Keywords: Amavata, Rheumatoid arthritis, Chikitsa, management, Chakradutta
One important plant based Ayurvedic drug i.e. (i.e. Bhaishajya Ratnavali) for its probable ern ch... more One important plant based Ayurvedic drug i.e. (i.e. Bhaishajya Ratnavali) for its probable ern chemical review in context of Amavata tains six ingredients and out of which five are plant based and one is mineral based ingredient. The Virya, Vipak and Karma of ingredients of Amavata (Rheumatoid arthritis). The Physicochemical study on this drug constituents, less moisture and less water soluble constituents. The Phytochemical study ducing sugars, saponin glycosides, phenolic compounds and gum phytocostitutents are indicated under short ultra vi der long ultra violet ray (366 nm) into the sample of this drug by thin layer chromatography (TLC) study.
Research Journal of Pharmacology and Pharmacodynamics, 2021
In herbal medicine, there is a substantial amount of variety of plants have been used to treat ne... more In herbal medicine, there is a substantial amount of variety of plants have been used to treat neurodegenerative disorders including Alzheimer's (AD)as well as other memory-related issues. Dementia is a neurological condition characterised by a progressive loss in emotional and cognitive abilities. Dementia is linked to a number of conditions like inadequate cerebral blood flow, poison toxicity, and other risk factors and conditions mitochondrial dysfunction, oxidative injury, and, in certain cases coexistence with other diseases like Alzheimer's disease (AD), Huntington's disease, Parkinson's syndrome (PD) and Attention Deficit Hyperactivity Disorder (ADHD).Despite the fact that there are well-established semi-synthetic medications for the treatment of AD and AD-related dementia, the majority of them have a number of side effects. As a result, conventional medicine offers a variety of plant-derived lead molecules that may be valuable in future medical studies. In th...
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