Papers by Clinton Orupabo
Advances in Biomedical and Health Sciences
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International Journal of Medicine and Medical Research, Mar 3, 2023
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Scholars International Journal of Anatomy and Physiology
Anthropological assessment becomes the sole available medium for identification of the deceased i... more Anthropological assessment becomes the sole available medium for identification of the deceased in most forensic cases. We hope therefore to assess metrically if the femur bone could be used to estimate the age and sex of individuals by focusing on some rare morphological parameters. The skeletal samples of the right femur from 105 individuals (78 males and 27 females), who are within the age range of 21 and 60 years were harvested. The male samples had 53 profiled and 25 specimens non-profiled for age, while the females had 10 profiled and 17 specimens non- profiled for age. Direct measurements were taken for the marrow cavity diameter (MCD) and cortical thickness or radius (CT or Cr) using a centimeter rule and a sliding digital caliper to the nearest 0.1mm.The Marrow Cavity Diameter in our study is higher in the male population (1.70± 0.05) than the female population (1.43± 0.05). This variation was statistically significant (P<0.05) using the student t-test. The radius or thi...
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Asian Journal of Advanced Research and Reports
Aims: The aim of our study is to investigate RNA patterns of a postmortem hair sample. The presen... more Aims: The aim of our study is to investigate RNA patterns of a postmortem hair sample. The present work intend therefore to study the quantitative analysis of Ribonucleic acids quality and quantity. Study Design: This is an experimental and descriptive study which used convenient sampling technique in sample selection. Methodology: The respondents of this study comprised of living subjects in Rivers State, Nigeria selected through convenient sampling technique. Hair Samples from participants were collected after informed consent using hair tweezers and labelled Ziploc bags. RNA was extracted using the TRI-reagent and its quality and quantity assessed using the Nanodrop. Concentration and purity of RNA were assessed by spectrophotometric analysis using NanoDrop 2000c. Results: RNA quality seems to diminish with time initially but improved at day 7 and 14, with an improved purity (1.94 and 2.03). However, at a later date the purity diminished further owing to possible degradation with...
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During pregnancy, there is decrease in maternal immunoglobulin levels due to suppression of mater... more During pregnancy, there is decrease in maternal immunoglobulin levels due to suppression of maternal immunity in order to prevent rejection of the foetal allograft. Hypertension influences the values of maternal immunoglobulins thereby affecting pregnancy outcome. This study was therefore conducted to determine the feto-maternal serum immunoglobulin levels in hypertensive and healthy mothers in University of Port Harcourt Teaching Hospital. Sixteen (16) pregnant women were randomly recruited for this study; 6 hypertensive and 10 healthy mothers. Serum samples of both mother and foetal umbilical cord were collected and analyzed for three immunoglobulins: IgG, IgM and IgA. The mean maternal IgG levels of mothers with hypertension and those in a healthy state were 968.33±163.27 mg/dl and 942.20±103.06 mg/dl respectively while their corresponding mean foetal IgG values were 1121.67±171.16 mg/dl and 987.00±120.74 mg/dl. Also, the mean maternal IgM levels of mothers with hypertension and those in a healthy state were 94.00±44.38 mg/dl and 61.90±17.95 mg/dl respectively while the mean maternal IgA levels of mothers with hypertension and those in a healthy state were 134.67±27.00 mg/dl and 92.60±34.28 mg/dl respectively. The result showed higher IgG, IgM and IgA immunoglobulins levels in hypertensive than non-hypertensive mothers. The levels of the mean foetal IgA and IgM were significantly low compared to foetal IgG, though higher in healthy mothers. This study had shown that hypertension increases the serum levels of maternal immunoglobulin thereby causing deleterious effects on the growing foetus.
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JBRA Assisted Reproduction, 2021
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Alcohol is a known substance in the society and readily abused. The consumption of alcohol has co... more Alcohol is a known substance in the society and readily abused. The consumption of alcohol has continued to increase among students in various institutions of learning across the world. This research work was carried out to ascertain the determinants and possible effects of alcohol consumption among tertiary education students. This is a cross-sectional study involving 121 students (39 males and 82 females) with ages <20years, 20-35years and >35years in first and second year of their studies. The study shows that students <20years consumed more alcohol (57.9%), followed by >35years (50%) and the students between 20-35years consumed less alcohol (48.2%). The study also shows that males (74.3%) consumed more alcohol than females (42.6%). Most respondents consumed alcohol to increase sexual libido and performance as well as reading and understanding. There was no marked variation in percentage alcohol consumption between first and second year students in this study, though ...
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Background: Desired conception is an important process among families in Africa, particularly whe... more Background: Desired conception is an important process among families in Africa, particularly when married. Many women have desired to conceive at their matrimonial homes but find it difficult to actualize their plans. This study was carried out to x-ray the determinants of delayed, desired conception among reproductive women of Port Harcourt. Materials & Method: This is a cross-sectional study involving 50 women who are within their reproductive period with age range 18-24years, 25-31years, 32-37years, 38-43years and 44-49years. A well structured self administered questionnaire was issued to each participant. Results: Data was analyzed with SPSS version 26 and Excel and P value < 0.05 was considered significant. The study shows that most women though married had delay in conception and this was predominant in women between 32-37years and 38-43years. Major factors implicated in causing delay to conception include uterine fibroid, alcohol consumption, abortions, contraceptive use ...
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International Journal of Research in Medical Sciences, 2020
Background: Fibroid is a gynaecological problem that affects women of reproductive age across the... more Background: Fibroid is a gynaecological problem that affects women of reproductive age across the globe especially among the black race. This study was done to evaluate the incidence of fibroid and its effects on fertility in Eleme Local Government Area.Methods: It is a cross-sectional study with 60 participants aged 18-28 years, 29-39 years, 40-49 years, 50-59 years and >60 years.Results: The study revealed that 90% of the respondents have fibroid and 10% do not have fibroid. The effects range from painful menstruation, heavy menses, irregular menstruation and infertility at the values of 63.3%, 48.3%, 51.7% and 86.8% respectively.Conclusions: Though the effects of fibroids are universal, our study population seems to show some effects more common to them.
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Academia Anatomica International, 2019
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American Journal of Medicine and Medical Sciences, 2018
During pregnancy, there is decrease in maternal immunoglobulin levels due to suppression of mater... more During pregnancy, there is decrease in maternal immunoglobulin levels due to suppression of maternal immunity in order to prevent rejection of the foetal allograft.Hypertension influences the values of maternal immunoglobulins thereby affecting pregnancy outcome. This study was therefore conducted to determine the feto – maternal serum immunoglobulin levels in hypertensive and healthy mothers in University of Port Harcourt Teaching Hospital. Sixteen (16) pregnant women were randomly recruited for this study; 6 hypertensive and 10 healthy mothers. Serum samples of both mother and foetal umbilical cord were collected and analyzed for three immunoglobulins: IgG, IgM and IgA. The mean maternal IgG levels of mothers with hypertension and those in a healthy state were 968.33±163.27 mg/dl and 942.20±103.06 mg/dl respectively while their corresponding mean foetal IgG values were 1121.67±171.16 mg/dl and 987.00±120.74 mg/dl. Also, the mean maternal IgM levels of mothers with hypertension and...
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Anatomy being a major course in medical school is generally believed to be the foundation subject... more Anatomy being a major course in medical school is generally believed to be the foundation subject of medicine. The aim of our study therefore is to determine the possible factors affecting study of clinical anatomy among Medical Laboratory students. The introduction of the study of clinical anatomy to medical laboratory students may not be entirely weird. This is a cross-sectional study carried out on undergraduate medical laboratory students of Rivers State University. 266 students (males=118, females=148) aged 15-38years participated in the study drawn from two hundred to five hundred levels. The percentage of students who like the anatomy subject in class 2, 3, 4 and 5 are 73.68%, 72.91%, 71.58% and 57.14% respectively. The data is statistically significant (p < 0.05) for students who like or dislike anatomy. There is no correlation between class level and number of students who passed at first attempt (r=0). There is no significant gender variation with first attempt pass in ...
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Arab Journal of Forensic Sciences and Forensic Medicine
Estimation of the sex of unknown skeletal remains is a daunting challenge, when only fragmented b... more Estimation of the sex of unknown skeletal remains is a daunting challenge, when only fragmented bones are available. For this reason, there is a need to study population specific histomorphometric features of bones to provide useful data for the process of identification. The purpose of this study was to estimate sex from six histomorphometric parameters of cortical bones in a cohort of Nigerian patients. The samples comprised non-pathologic bones collected from 29 patients (12 females and 17 males) between the ages of 35 to 85 years during orthopaedic procedures. The modified Frost’s manual method was used to prepare the histological sections of the cortical bones. The parameters evaluated were number of primary osteons (Os-p), number of secondary osteons (Os-s), osteon fragments (Os-f), non-Haversian canal (N-Hc), area of Haversian canal (Area Hc), and Haversian canal diameter (HCD). The data obtained were analyzed using SPSS version 23.0. Tests for sex differences were done using...
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American Journal of Medicine and Medical Sciences, 2018
The aim of the study is to quantify the facial soft tissue profile of Ikwerre children between th... more The aim of the study is to quantify the facial soft tissue profile of Ikwerre children between the ages of 5 and 12 in a population sample of 202 persons (101 males and 101 females) randomly selected from various Children Centre in Port Harcourt. Standard photographic measurements were taken in the natural head position to determine the mentocervical angle (MCA), angle of facial convexity (AFC) and angle of total facial convexity (ATFC). The data obtained were tested with z test, student t test and Anova at 0.05 statistical significant levels. The mean value for the MCA for boys and girls were 92.67 degrees and 93.26 degrees respectively; AFC was 161.27 degrees for boys and 159.94 degrees for girls; ATFC for boys and girls were 150.77 degrees and 151.51 degrees respectively. The mean MCA for the lowest age group studied (5 – 6 years) was 95.67 degrees for boys and 94.44 degrees for girls whereas that for the highest age group (11 – 12 years) was 90 degrees for boys and 90.35 degrees...
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Background. Age estimation is crucial in creating the biological profile of unknown skeletal rema... more Background. Age estimation is crucial in creating the biological profile of unknown skeletal remains and recently there is emphasis on the need to develop population specific forensic baseline data for easy identification of these remains. Objective. The aim of this study is to estimate age from the histomorphometric features of the bones of Nigerians. Methods. Fragments of non-pathologic bone samples were collected during orthopaedic procedures. Ground sections were prepared using Modified Frost’s manual method of bone preparation to determine the following histologic parameters; haversian canal diameter (HCD), primary and secondary osteons, number of osteon fragments and non-haversian canal as well as haversian canal area (HCA). 29 subjects aged 35 to 85 years old were used for the study. Bone fragments included samples from the femur, tibia, humerus, and the vertebrae. Data obtained were subjected to descriptive statistics, Pearson’s correlation, bivariate regression equation, St...
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Papers by Clinton Orupabo