Papers by Charlotte Ayima
HSOA journal of physical medicine, rehabilitation & disabilities, Apr 23, 2023
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African Journal of Disability, Dec 14, 2022
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Research Square (Research Square), Sep 6, 2022
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BMC Public Health, Nov 14, 2015
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Research Square (Research Square), Aug 30, 2021
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Background: Retention in care and transition to adulthood are critical for children and adolescen... more Background: Retention in care and transition to adulthood are critical for children and adolescents living with HIV on Antiretroviral Therapy (ART) in HIV treatment programs. This study aimed to determine the incidence and predictors of loss-to-follow-up (LTFU) in the context of ongoing crisis caused by an armed conflict in the Northwest and Southwest Regions of Cameroon, where staff in HIV treatment programs may face unique challenges of retention of children/adolescents. Methods: We employed a multi-stage mixed method design in which we conducted a retrospective cohort study to determine incidence and risk factors for LTFU through data abstraction from medical records of children and adolescents from five (5) ART treatment centers, followed by seventeen (17) key informant interviews conducted with healthcare workers to gain further insights into the reasons for LTFU among children and adolescents enrolled between January 2018 to December 2021. Kaplan–Meier plots were used to deter...
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Background Up to the 21st century, traditional, complementary and alternative medicine(TCAM) is s... more Background Up to the 21st century, traditional, complementary and alternative medicine(TCAM) is still used despite the wide spread of orthodox medicine. The magnitude, predictors and types of herbal remedies used for COVID-19 are assessed to tailor evidence based policy and drug formulation against COVID-19. Methods A community based cross sectional study was conducted among 1100 respondents from nine (9) communities selected in three health districts from May to July 2020. Pretested structured questionnaire were used to collect data from selected households on the use of TCAM, predictors as well as on the herbal preparations used for COVID-19. Nineteen (19) traditional healers were also interviewed on the types of herbal preparations use on patients tested or suspected for COVID-19 and the signs and symptoms identified. P-value < 0.05 were considered to be statistically significant in multivariate logistic regression analysis. Atlas ti V 7.5 was used for types of herbal species ...
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Abstract: Background: The introduction and widespread use of combination antiretroviral therapy r... more Abstract: Background: The introduction and widespread use of combination antiretroviral therapy referred to as highly active antiretroviral therapy (HAART) in the mid 1990’s, has led HIV-infected individuals to experience a dramatic decline in immunodeficiency-related events and death. There is growing concern on metabolic complications associated with HIV and HAART which may increase cardiovascular risk and disease. The aim of this study was to investigate the cardiovascular risk profile of HIV/AIDS patients receiving HAART and those not receiving HAART at HIV/AIDS treatment centres in the South West Region of Cameroon. Methods: Consenting participants, who had been receiving HAART, were compared with HAART naive participants. A questionnaire was administered; anthropometric and blood pressure measurements were recorded under standard conditions. Blood samples were obtained for the determination of plasma glucose and lipid levels. Results: Two hundred and fifteen participants were ...
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Background: Cholera is an acute diarrheal disease caused by the bacterium, Vibrio cholerae. A cho... more Background: Cholera is an acute diarrheal disease caused by the bacterium, Vibrio cholerae. A cholera epidemic occurred in Cameroon in 2010. After a cholera-free period at the end of 2010, new cases started appearing in early 2011. The disease affected 23,152 people and killed 843, with the South West Region registering 336 cases and 13 deaths. Hence, we assessed the risk factors of cholera epidemic in the Buea Health District to provide evidence-based cholera guidelines. Methods: We conducted an unmatched case–control study. Cases were identified from health facility records and controls were neighbours of the cases in the same community. We interviewed 135 participants on socio-economic, household hygiene, food and water exposures practices using a semi-structured questionnaire. Data was analyzed using STATA. Fisher exact test and logistic regression were computed. P < 0.05 was considered to be statistically significant. Results: The 135 participants included 34 (25.2 %) choler...
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Background: Tuberculosis is the commonest infection among HIV/AIDS patients. This co-infection co... more Background: Tuberculosis is the commonest infection among HIV/AIDS patients. This co-infection constitutes a major death threat in the world. There is paucity of data about renal disease amongst patients on HAART and DOTS therapy in Cameroon. Methods: This was a hospital-based cross-sectional study in the Buea, Limbe and Kumba government Hospitals. Spectrophotometric method was used for the quantitative determination of serum creatinine, urea, albumin and total protein levels. Glomerular filtration rate was estimated using the MDRD method. The student’s t test, ANOVA and logistic regression were used to analyse the data. Results: Out of 200 participants, 101 (50.5 %) were males. The ages ranged from 21 to 65 years with a mean age of 38.04 ± 10.52 years. Compared to adults on DOTS alone, adults on HAART alone had a significantly higher prevalence of eGFR <60 ml/min/1.73 m2 (10/70 (14.3 %) vs. 1/70 (1.4 %), OR = 11.5 [1.4–92.5], p = 0.02) while more participants on HAART/DOTS had s...
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Background: Traditional medicines are an important part of healthcare in sub-Saharan Africa. Trad... more Background: Traditional medicines are an important part of healthcare in sub-Saharan Africa. Traditional medicine has long been used in Cameroon and the world over in the prevention and treatment of diseases, physical and mental disorders as well as social imbalance. Building successful disease management programs that are sensitive to traditional medicine practices, achieving primary and Universal Health Coverage (UHC), will require an understanding of their current use, and roles as well as the state of regulation. This review was done to identify the role, research gaps, and suggest perspectives for future research as far as traditional medicine is concerned in Cameroon. Methods: Database searches were done through the internet using Google scholar, Google, PubMed, Sci-hub, books, theses, and related websites involving the use of key words in both English and French Languages. Out of the 93 articles only 12 original articles and 3 reviews met the inclusion criteria. Results: Stud...
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BMJ Global Health, 2017
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BMC Public Health, 2015
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The Open AIDS Journal, 2015
Background :The introduction and widespread use of combination antiretroviral therapy referred to... more Background :The introduction and widespread use of combination antiretroviral therapy referred to as highly active antiretroviral therapy (HAART) in the mid 1990’s, has led HIV-infected individuals to experience a dramatic decline in immunodeficiency-related events and death. There is growing concern on metabolic complications associated with HIV and HAART which may increase cardiovascular risk and disease. The aim of this study was to investigate the cardiovascular risk profile of HIV/AIDS patients receiving HAART and those not receiving HAART at HIV/AIDS treatment centres in the South West Region of Cameroon.Methods :Consenting participants, who had been receiving HAART, were compared with HAART naive participants. A questionnaire was administered; anthropometric and blood pressure measurements were recorded under standard conditions. Blood samples were obtained for the determination of plasma glucose and lipid levels.Results :Two hundred and fifteen participants were recruited, 1...
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BMC Public Health, 2015
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BMC Cardiovascular Disorders, 2015
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BMC Infectious Diseases, 2009
Background HIV infection has been modifying both the epidemiology and outcome of parasitic infect... more Background HIV infection has been modifying both the epidemiology and outcome of parasitic infections. Hence, this study was undertaken to determine the prevalence of intestinal parasitic infection among people with and without HIV infection and its association with diarrhea and CD4 T-cell count. Methods A cross-sectional study was conducted at Hawassa Teaching and Referral Hospital focusing on HIV positive individuals, who gave blood for CD4 T-cell count at their first enrolment and clients tested HIV negative from November, 2008 to March, 2009. Data on socio-demographic factors and diarrhea status were obtained by interviewing 378 consecutive participants (214 HIV positive and 164 HIV negative). Stool samples were collected from all study subjects and examined for parasites using direct, formol-ether and modified acid fast stain techniques. Results The prevalence of any intestinal parasitic infection was significantly higher among HIV positive participants. Specifically, rate of i...
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African Journal of Disability
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Papers by Charlotte Ayima