Background: Adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in... more Background: Adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in late childhood or adolescence. Instead of growing straight, the spine develops a side-to-side curvature, usually in an elongated "S" or "C" shape; the bones of the spine are also slightly twisted or rotated. To prevent further curve progression and obtain a balanced spine, surgery remains the mainstay of treatment for idiopathic scoliosis (IS). Objective: This study aimed to discuss three dimensional surgical techniques used for correction of adolescent idiopathic scoliosis, evaluating their feasibility, efficacy and safety. Patients and methods: This study was conducted in Mansoura University Hospital and Alexandria University Hospitals between September 2018 and April 2021. 3D surgical correction was performed for 91 patients complaining of idiopathic scoliosis, and not responding to conservative measures and not associated with neurological affection. Results: Acc...
AimIntracranial haemorrhage (ICH) in infancy is a rare life‐threatening event. The aim of this re... more AimIntracranial haemorrhage (ICH) in infancy is a rare life‐threatening event. The aim of this review is to highlight the association of ICH and potentially preventable vitamin K deficiency and to describe risk factors, presentation and outcome.MethodsOriginal published data on ICH related to vitamin K deficiency during 2008–2012 were extracted from records of participating centres in Egypt (Cairo and Delta region). Full data on 70 infants (0–24 weeks) have been reported in three publications.ResultsThe first study involved premature infants where ICH was potentially preventable with administration of parenteral vitamin K prophylactic doses to mothers ahead of imminent preterm delivery. The other 2 studies involved term newborns and infants. ICH due to early or classic vitamin K deficiency was reported in nine patients while 44 were due to late vitamin K deficiency. Main risk factors for late onset were exclusive breastfeeding, persistent diarrhoea and/or prolonged antibiotic therap...
Background: Coccydynia is a common complaint which is usually self-limited and tolerable. Althoug... more Background: Coccydynia is a common complaint which is usually self-limited and tolerable. Although most of these patients respond dramatically to conservative measures, some patients need more complex plane of treatment. In these conditions, the cause of coccydynia can be complex and multifactorial. Patients and methods: A total of 8 cases were included in the study. All cases received medical treatment for 9 months before surgery. Complete coccygectomy was performed for all cases. Post-operative outcomes were measured according to the degree of pain relief. Results: The mean age of the included cases was 43.87 years (range, 39 – 52). A total of 5 females (62.5%) and 3 males (37.5%) were included. The mean preoperative VAS score was 9 (range, 8 – 10), while post-operatively, it decreased significantly down to 2 (range, 1 – 3). Excellent postoperative outcomes were achieved in 6 cases (75%) whereas good outcomes were obtained in the remaining 2 cases (25%). Conclusion: Although conse...
Journal of B.U.ON. : official journal of the Balkan Union of Oncology
This study was undertaken to determine the effect of adjuvant chemotherapy combined with reduced-... more This study was undertaken to determine the effect of adjuvant chemotherapy combined with reduced-dose craniospinal irradiation (CSI) on survival and neurocognitive sequelae of radiotherapy (RT) in patients with average- risk medulloblastoma above the age of 3 years. Thirty-three children between 3 and 10 years of age with average-risk medulloblastoma were treated with postoperative reduced-dose CSI (24.0 Gy) and 30.6 Gy of local RT (total of 54.6 Gy) and then with adjuvant chemotherapy consisting of cisplatin, vincristine, and cyclophosphamide every 4 weeks for 8 cycles. At 5 years, event-free survival (EFS) was 79%, while overall survival (OS) was 85%. Sites of relapse were local in 3%, neuraxis in 9% and both local and neuraxis in 9% of the patients. Chemotherapy was well tolerated. Hematopoietic toxicity was the most predominant side effect followed by vomiting and ototoxicity. No grade III or IV nephrotoxicity or neurotoxicity and no treatment-related deaths were encountered. In...
Object Although the incidence of vitamin K deficiency bleeding (VKDB) in neonates has dramaticall... more Object Although the incidence of vitamin K deficiency bleeding (VKDB) in neonates has dramatically decreased in the developed world since the adoption of routine vitamin K prophylaxis, in developing countries the incidence is still high. Intracranial hemorrhage (ICH) is the most dangerous complication. Early recognition and management are important to decrease the mortality rate and neurological sequelae. The authors conducted a prospective study between January 2008 and June 2010. They included all full-term neonates referred to the Department of Neurosurgery at Mansoura University Children's Hospital with ICH complicating VKDB and necessitating surgical evacuation. The objective was to evaluate the clinical presentation, diagnosis, hospital course, and outcome of ICH in full-term neonates with VKDB after surgical evacuation. Methods Thirty-two neonates with ICH due to VKDB were included. Diagnosis and classification of ICH were based on detailed history, physical examination, ...
Background: Adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in... more Background: Adolescent idiopathic scoliosis is an abnormal curvature of the spine that appears in late childhood or adolescence. Instead of growing straight, the spine develops a side-to-side curvature, usually in an elongated "S" or "C" shape; the bones of the spine are also slightly twisted or rotated. To prevent further curve progression and obtain a balanced spine, surgery remains the mainstay of treatment for idiopathic scoliosis (IS). Objective: This study aimed to discuss three dimensional surgical techniques used for correction of adolescent idiopathic scoliosis, evaluating their feasibility, efficacy and safety. Patients and methods: This study was conducted in Mansoura University Hospital and Alexandria University Hospitals between September 2018 and April 2021. 3D surgical correction was performed for 91 patients complaining of idiopathic scoliosis, and not responding to conservative measures and not associated with neurological affection. Results: Acc...
AimIntracranial haemorrhage (ICH) in infancy is a rare life‐threatening event. The aim of this re... more AimIntracranial haemorrhage (ICH) in infancy is a rare life‐threatening event. The aim of this review is to highlight the association of ICH and potentially preventable vitamin K deficiency and to describe risk factors, presentation and outcome.MethodsOriginal published data on ICH related to vitamin K deficiency during 2008–2012 were extracted from records of participating centres in Egypt (Cairo and Delta region). Full data on 70 infants (0–24 weeks) have been reported in three publications.ResultsThe first study involved premature infants where ICH was potentially preventable with administration of parenteral vitamin K prophylactic doses to mothers ahead of imminent preterm delivery. The other 2 studies involved term newborns and infants. ICH due to early or classic vitamin K deficiency was reported in nine patients while 44 were due to late vitamin K deficiency. Main risk factors for late onset were exclusive breastfeeding, persistent diarrhoea and/or prolonged antibiotic therap...
Background: Coccydynia is a common complaint which is usually self-limited and tolerable. Althoug... more Background: Coccydynia is a common complaint which is usually self-limited and tolerable. Although most of these patients respond dramatically to conservative measures, some patients need more complex plane of treatment. In these conditions, the cause of coccydynia can be complex and multifactorial. Patients and methods: A total of 8 cases were included in the study. All cases received medical treatment for 9 months before surgery. Complete coccygectomy was performed for all cases. Post-operative outcomes were measured according to the degree of pain relief. Results: The mean age of the included cases was 43.87 years (range, 39 – 52). A total of 5 females (62.5%) and 3 males (37.5%) were included. The mean preoperative VAS score was 9 (range, 8 – 10), while post-operatively, it decreased significantly down to 2 (range, 1 – 3). Excellent postoperative outcomes were achieved in 6 cases (75%) whereas good outcomes were obtained in the remaining 2 cases (25%). Conclusion: Although conse...
Journal of B.U.ON. : official journal of the Balkan Union of Oncology
This study was undertaken to determine the effect of adjuvant chemotherapy combined with reduced-... more This study was undertaken to determine the effect of adjuvant chemotherapy combined with reduced-dose craniospinal irradiation (CSI) on survival and neurocognitive sequelae of radiotherapy (RT) in patients with average- risk medulloblastoma above the age of 3 years. Thirty-three children between 3 and 10 years of age with average-risk medulloblastoma were treated with postoperative reduced-dose CSI (24.0 Gy) and 30.6 Gy of local RT (total of 54.6 Gy) and then with adjuvant chemotherapy consisting of cisplatin, vincristine, and cyclophosphamide every 4 weeks for 8 cycles. At 5 years, event-free survival (EFS) was 79%, while overall survival (OS) was 85%. Sites of relapse were local in 3%, neuraxis in 9% and both local and neuraxis in 9% of the patients. Chemotherapy was well tolerated. Hematopoietic toxicity was the most predominant side effect followed by vomiting and ototoxicity. No grade III or IV nephrotoxicity or neurotoxicity and no treatment-related deaths were encountered. In...
Object Although the incidence of vitamin K deficiency bleeding (VKDB) in neonates has dramaticall... more Object Although the incidence of vitamin K deficiency bleeding (VKDB) in neonates has dramatically decreased in the developed world since the adoption of routine vitamin K prophylaxis, in developing countries the incidence is still high. Intracranial hemorrhage (ICH) is the most dangerous complication. Early recognition and management are important to decrease the mortality rate and neurological sequelae. The authors conducted a prospective study between January 2008 and June 2010. They included all full-term neonates referred to the Department of Neurosurgery at Mansoura University Children's Hospital with ICH complicating VKDB and necessitating surgical evacuation. The objective was to evaluate the clinical presentation, diagnosis, hospital course, and outcome of ICH in full-term neonates with VKDB after surgical evacuation. Methods Thirty-two neonates with ICH due to VKDB were included. Diagnosis and classification of ICH were based on detailed history, physical examination, ...
Uploads
Papers