Diallyl sulphide (DAS) is a sulphur-containing volatile compound present in garlic (Allium sativu... more Diallyl sulphide (DAS) is a sulphur-containing volatile compound present in garlic (Allium sativum). It has been shown to inhibit a number of chemically induced forms of cancer in experimental animals. The present study demonstrates the inhibitory effect of DAS on the development of diethylnitrosamine (DEN) initiated and 2-acetyl-aminofluorene (2-AAF) promoted preneoplastic altered hepatic foci (AHF) in Wistar rats. AHF were scored and analysed by quantitative stereology using the Image Analysis system from frozen liver sections stained for biological markers, namely glutathione S-transferase, placental form (GST-P), gamma-glutamyl transpeptidase (GGT), adenosine triphosphatase (ATPase), glucose-6-phosphatase (G6 Pase) and alkaline phosphatase (AlkPase). DAS-supplemented rats were found to restore the near-normal levels of enzymes GST-P and GGT when exposed to DEN and 2-AAF. DAS administration following DEN and 2-AAF exposure led to the restoration of enzymic activity of ATPase, G6 Pase and AlkPase, as evident by number and area of the foci. These findings suggest the protective role of DAS in rat hepatocarcinogenesis, by suppressing DEN- and 2-AAF-induced AHF development.
Journal of Education, Society and Behavioural Science, 2021
The purpose of the study was to investigate the impact of extracurricular activities on the acade... more The purpose of the study was to investigate the impact of extracurricular activities on the academic performance and students’ assessment towards the extra-curricular activities at higher secondary school ( HSS) level. The sample consisted of 156 students from five different classes (IX-XII). The classes were selected randomly. The study used a mixed method approach. The quantitative component integrated was 24 items of 4 Likert scale survey questionnaires categorized under three themes. The qualitative component incorporated students’ assessment on impact of extracurricular activities in academic performance were collected through open-ended questions. Data form survey questionnaires were analyzed using descriptive analysis (means and standard deviation) and inferential t-test was use for analysis of hypothesis. The qualitative raw date was thematically analyzed (transcribed, coded and categorized). The findings of the study indicated that that student who participated in extra-cur...
Diallyl sulphide (DAS) is a sulphur-containing volatile compound present in garlic (Allium sativu... more Diallyl sulphide (DAS) is a sulphur-containing volatile compound present in garlic (Allium sativum). It has been shown to inhibit a number of chemically induced forms of cancer in experimental animals. The present study demonstrates the inhibitory effect of DAS on the development of diethylnitrosamine (DEN) initiated and 2-acetyl-aminofluorene (2-AAF) promoted preneoplastic altered hepatic foci (AHF) in Wistar rats. AHF were scored and analysed by quantitative stereology using the Image Analysis system from frozen liver sections stained for biological markers, namely glutathione S-transferase, placental form (GST-P), gamma-glutamyl transpeptidase (GGT), adenosine triphosphatase (ATPase), glucose-6-phosphatase (G6 Pase) and alkaline phosphatase (AlkPase). DAS-supplemented rats were found to restore the near-normal levels of enzymes GST-P and GGT when exposed to DEN and 2-AAF. DAS administration following DEN and 2-AAF exposure led to the restoration of enzymic activity of ATPase, G6 Pase and AlkPase, as evident by number and area of the foci. These findings suggest the protective role of DAS in rat hepatocarcinogenesis, by suppressing DEN- and 2-AAF-induced AHF development.
Journal of Education, Society and Behavioural Science, 2021
The purpose of the study was to investigate the impact of extracurricular activities on the acade... more The purpose of the study was to investigate the impact of extracurricular activities on the academic performance and students’ assessment towards the extra-curricular activities at higher secondary school ( HSS) level. The sample consisted of 156 students from five different classes (IX-XII). The classes were selected randomly. The study used a mixed method approach. The quantitative component integrated was 24 items of 4 Likert scale survey questionnaires categorized under three themes. The qualitative component incorporated students’ assessment on impact of extracurricular activities in academic performance were collected through open-ended questions. Data form survey questionnaires were analyzed using descriptive analysis (means and standard deviation) and inferential t-test was use for analysis of hypothesis. The qualitative raw date was thematically analyzed (transcribed, coded and categorized). The findings of the study indicated that that student who participated in extra-cur...
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