i am an academician, with special interest in writing.Professionally I am a neurologist, who enjoys treating patients, more than indulging in research.Takes interest and participates in different sports.
Mollaret's meningitis is defined as a benign recurrent aseptic meningitis characterized by t... more Mollaret's meningitis is defined as a benign recurrent aseptic meningitis characterized by three to ten episodes of fever and signs of meningeal irritation lasting between 2 to 5 days, associated with spontaneous recovery. Mollaret in 1944 described ...
Original Research Article Magnetic resonance imaging (MRI) is the preferred investigation for mos... more Original Research Article Magnetic resonance imaging (MRI) is the preferred investigation for most spinal diseases. However, determining the cause of radicular pain extending into the lower limb is complicated as it is often multifactorial and anatomical abnormalities detected by MRI are common in the spine and may not necessarily translate into clinical symptoms. So in the evaluation of a patient of lumbosacral radicular pain in the lower limbs, it is essential to correlate the clinical symptoms and signs with the findings detected in the MRI to arrive at a correct diagnosis and arrange an appropriate management. So this study was done to see the correlation between clinically and Magnetic Resonance Imaging detected lumbosacral radiculopathy in patients with low back pain. It was a cross sectional descriptive study in which 30 male and 10 female patients suffering from low back pain with radiation to the lower limbs were purposively selected. 67.5% of patients were between 20 to 50...
Stroke ranks first in frequency among all the neurological diseases of adult life and about 50% o... more Stroke ranks first in frequency among all the neurological diseases of adult life and about 50% of all neurological disorders in a hospital are of this type. It is the third leading cause of death throughout the world. The purpose of the present study was to find out the presence or absence of haemorrhage or infarct and to detect the early signs of stroke on the basis of CT scanning. Three-hundred twenty one consecutive acute stroke patients (mean age 64 ±9.75 years) were included in our study. Each underwent cranial computed tomography without intravenous contrast injection within the first 24 hours. CT findings of stroke were analyzed using SPSS software. Among 321 patients, 209(65.11%) had ischemic stroke, 99(30.84%) had parenchymal haemorrhage and 13(4.05%) had subarachnoid haemorrhage. Total amount of haemorrhagic stroke was 112(34.89%). Early CT findings of ischaemic stroke were low attenuation area (83.25%), sulcal effacement (69.89%), loss of the insular ribbon (17.70%), hyp...
Journal of National Institute of Neurosciences Bangladesh
Background: Recognition of factors affecting morbidity and mortality of a disease helps in the pr... more Background: Recognition of factors affecting morbidity and mortality of a disease helps in the proper management of a disease. CT scan of Brain is an essential investigation for all stroke patients. Identifying different characteristics of the CT findings of stroke patients which affect morbidity and mortality will help in the specific management of stroke patients. Thus this study was done to identify such factors from CT scan of Brain which will help in the proper management of stroke patients. Objectives: The aim of this present study was to determine the 7th and 28th days’ mortality rate of acute intracerebral hemorrhagic stroke and to determine the predictors of mortality. Methodology: Consecutive CT scan proven stroke patients following ICH were studied in the department of Radiology & Imaging at Rajshahi Medical College, Rajshahi, Bangladesh in collaboration with the Department of Neurology of Rajshahi Medical College, Rajshahi from January 2012 to December 2013. Site, size a...
Journal of Bangladesh College of Physicians and Surgeons
One of the most common and useful forms of medical intervention is anticoagulant therapy and it i... more One of the most common and useful forms of medical intervention is anticoagulant therapy and it is the mainstay of treatment and prevention of thrombosis in different clinical settings, like atrial fibrillation (AF), acute coronary syndrome (ACS), acute venous thromboembolism (VTE), and in patients undergoing invasive cardiac procedures. More than 6 million patients in the United States receive long-term anticoagulation therapy for the prevention of thromboembolism due to AF, placement of a mechanical heart-valve prosthesis, or VTE.1 For more than 60 years, until 2009, warfarin and other vitamin K antagonists were the only class of oral anticoagulants (OAC) available. Although these drugs are highly effective in prevention of TE, their use is limited by a narrow therapeutic index that necessitates frequent monitoring and dose adjustments. This results in substantial risk and inconvenience, leading to inadequate anticoagulant prophylaxis. Recently some new OAC have been marketed whic...
Neuropathic pain (NeP) is caused by a lesion to the somatosensory system, leading to pain in a bo... more Neuropathic pain (NeP) is caused by a lesion to the somatosensory system, leading to pain in a body region related to the injured nervous structure. It leads to long-term changes in both peripheral and central neuronal networks and is associated with suffering and decreased quality of life. NeP can be diagnosed clinically and specific tests can confirm either the site of neuronal lesion or the topographical distribution of the deficit related to the pain. Different from nociceptive pain in which pain is caused by the activation of peripheral nerve endings, usually secondary to inflammation, NeP does not respond to usual analgesics. Its pharmacological treatment relies on the use of certain anticonvulsants and antidepressants that are able to decrease pain intensity and improve quality of life in a proportion of patients. Intensive research is being performed to better tailor treatment to individual patients and to develop more efficacious medications to relieve NeP in those who do not respond to current first-line therapy.
Headache is a universal problem. Of all the types of headache, the commonest is Tension-type Head... more Headache is a universal problem. Of all the types of headache, the commonest is Tension-type Headache. The word 'tension' implies that this type of headache can be attributed entirely to tension or stress, which may make people with this type of headache reluctant to consult a physician. Physicians misperceptions that tension-type headache are mild, benign, self-treatable and occur solely due to stress may further trivialize the problem. Thus this disease is often under-diagnosed and not treated properly. This article describes the disease and its management and is being published to increases awareness of the disease amongst the physicians. doi: 10.3329/taj.v17i2.3462 TAJ 2004; 17(2): 121-128
Background and purpose: Stroke is a leading cause of mortality and morbidity in both developed as... more Background and purpose: Stroke is a leading cause of mortality and morbidity in both developed as well as developing countries. The clinical presentation of stroke depending on the site and extent of lesions. For the management purpose it is important to know whether we are dealing with a bleed or an infarct. Methodology: Computed Tomography (CT scan) is available most of the tertiary level hospitals in Bangladesh. This study was carried out to compare clinical diagnosis of stroke with Computed tomography (CT) scan findings in ascertaining the type of stroke (hemorrhagic or ischemic). Materials and methods: This cross-sectional comparative study was conducted in the Department of Neurology, Rajshahi Medical College Hospital during the period of January 2010 to December 2010. Total 200 stroke patients were selected by purposive sampling technique on the basis of inclusion and exclusion criteria as the study sample. . CT brain scan was done for all the patients. The clinical diagnosis...
Epilepsy is a neurological problem which is a cause of sufferings for the common people because o... more Epilepsy is a neurological problem which is a cause of sufferings for the common people because of lack of proper scientific knowledge. The incidence of epilepsy is about 0.3 to 0.5% while the prevalence is about 5 to 10 people per 1000. Newer concepts about aetiopathogenesis, classification and treatment modalities are described in brief in this review article. DOI: http://dx.doi.org/10.3329/taj.v14i2.8398 TAJ 2001; 14(2): 99-103
Peripheral neuropathy is common in chronic renal failure patients and its early detection and tr... more Peripheral neuropathy is common in chronic renal failure patients and its early detection and treatment reduces the sufferings of these patients. Studies of neuropathy in ESKD have demonstrated prevalence rates which vary from 60 to 100%. The striking pathologic features of peripheral neuropathy in patients of CRF are axonal degeneration in the most distal nerve trunks with secondary segmental demyelination. The most frequent clinical features are those of large-fiber involvement, with paresthesias, reduction in deep tendon reflexes, impaired vibration sense, weakness and muscle wasting. Patients of CRF may present with mononeuropathies or autonomic failure also. The exact cause of nerve involvement has not been identified but the middle molecule hypothesis is widely accepted. Dialysis in any form fails to improve the neuropathy but renal transplantation does improve the neurological complications. This review details the various features of neuropathy in patients of chronic renal ...
Parkinson's disease is a disease of motor manifestations but non-motor symptoms are also com... more Parkinson's disease is a disease of motor manifestations but non-motor symptoms are also common in Parkinson's disease. Little emphasis is put on non-motor symptoms of PD and there is little data on the relationship of non-motor symptoms to different aspects of the patient and the ...
Mollaret's meningitis is defined as a benign recurrent aseptic meningitis characterized by t... more Mollaret's meningitis is defined as a benign recurrent aseptic meningitis characterized by three to ten episodes of fever and signs of meningeal irritation lasting between 2 to 5 days, associated with spontaneous recovery. Mollaret in 1944 described ...
Original Research Article Magnetic resonance imaging (MRI) is the preferred investigation for mos... more Original Research Article Magnetic resonance imaging (MRI) is the preferred investigation for most spinal diseases. However, determining the cause of radicular pain extending into the lower limb is complicated as it is often multifactorial and anatomical abnormalities detected by MRI are common in the spine and may not necessarily translate into clinical symptoms. So in the evaluation of a patient of lumbosacral radicular pain in the lower limbs, it is essential to correlate the clinical symptoms and signs with the findings detected in the MRI to arrive at a correct diagnosis and arrange an appropriate management. So this study was done to see the correlation between clinically and Magnetic Resonance Imaging detected lumbosacral radiculopathy in patients with low back pain. It was a cross sectional descriptive study in which 30 male and 10 female patients suffering from low back pain with radiation to the lower limbs were purposively selected. 67.5% of patients were between 20 to 50...
Stroke ranks first in frequency among all the neurological diseases of adult life and about 50% o... more Stroke ranks first in frequency among all the neurological diseases of adult life and about 50% of all neurological disorders in a hospital are of this type. It is the third leading cause of death throughout the world. The purpose of the present study was to find out the presence or absence of haemorrhage or infarct and to detect the early signs of stroke on the basis of CT scanning. Three-hundred twenty one consecutive acute stroke patients (mean age 64 ±9.75 years) were included in our study. Each underwent cranial computed tomography without intravenous contrast injection within the first 24 hours. CT findings of stroke were analyzed using SPSS software. Among 321 patients, 209(65.11%) had ischemic stroke, 99(30.84%) had parenchymal haemorrhage and 13(4.05%) had subarachnoid haemorrhage. Total amount of haemorrhagic stroke was 112(34.89%). Early CT findings of ischaemic stroke were low attenuation area (83.25%), sulcal effacement (69.89%), loss of the insular ribbon (17.70%), hyp...
Journal of National Institute of Neurosciences Bangladesh
Background: Recognition of factors affecting morbidity and mortality of a disease helps in the pr... more Background: Recognition of factors affecting morbidity and mortality of a disease helps in the proper management of a disease. CT scan of Brain is an essential investigation for all stroke patients. Identifying different characteristics of the CT findings of stroke patients which affect morbidity and mortality will help in the specific management of stroke patients. Thus this study was done to identify such factors from CT scan of Brain which will help in the proper management of stroke patients. Objectives: The aim of this present study was to determine the 7th and 28th days’ mortality rate of acute intracerebral hemorrhagic stroke and to determine the predictors of mortality. Methodology: Consecutive CT scan proven stroke patients following ICH were studied in the department of Radiology & Imaging at Rajshahi Medical College, Rajshahi, Bangladesh in collaboration with the Department of Neurology of Rajshahi Medical College, Rajshahi from January 2012 to December 2013. Site, size a...
Journal of Bangladesh College of Physicians and Surgeons
One of the most common and useful forms of medical intervention is anticoagulant therapy and it i... more One of the most common and useful forms of medical intervention is anticoagulant therapy and it is the mainstay of treatment and prevention of thrombosis in different clinical settings, like atrial fibrillation (AF), acute coronary syndrome (ACS), acute venous thromboembolism (VTE), and in patients undergoing invasive cardiac procedures. More than 6 million patients in the United States receive long-term anticoagulation therapy for the prevention of thromboembolism due to AF, placement of a mechanical heart-valve prosthesis, or VTE.1 For more than 60 years, until 2009, warfarin and other vitamin K antagonists were the only class of oral anticoagulants (OAC) available. Although these drugs are highly effective in prevention of TE, their use is limited by a narrow therapeutic index that necessitates frequent monitoring and dose adjustments. This results in substantial risk and inconvenience, leading to inadequate anticoagulant prophylaxis. Recently some new OAC have been marketed whic...
Neuropathic pain (NeP) is caused by a lesion to the somatosensory system, leading to pain in a bo... more Neuropathic pain (NeP) is caused by a lesion to the somatosensory system, leading to pain in a body region related to the injured nervous structure. It leads to long-term changes in both peripheral and central neuronal networks and is associated with suffering and decreased quality of life. NeP can be diagnosed clinically and specific tests can confirm either the site of neuronal lesion or the topographical distribution of the deficit related to the pain. Different from nociceptive pain in which pain is caused by the activation of peripheral nerve endings, usually secondary to inflammation, NeP does not respond to usual analgesics. Its pharmacological treatment relies on the use of certain anticonvulsants and antidepressants that are able to decrease pain intensity and improve quality of life in a proportion of patients. Intensive research is being performed to better tailor treatment to individual patients and to develop more efficacious medications to relieve NeP in those who do not respond to current first-line therapy.
Headache is a universal problem. Of all the types of headache, the commonest is Tension-type Head... more Headache is a universal problem. Of all the types of headache, the commonest is Tension-type Headache. The word 'tension' implies that this type of headache can be attributed entirely to tension or stress, which may make people with this type of headache reluctant to consult a physician. Physicians misperceptions that tension-type headache are mild, benign, self-treatable and occur solely due to stress may further trivialize the problem. Thus this disease is often under-diagnosed and not treated properly. This article describes the disease and its management and is being published to increases awareness of the disease amongst the physicians. doi: 10.3329/taj.v17i2.3462 TAJ 2004; 17(2): 121-128
Background and purpose: Stroke is a leading cause of mortality and morbidity in both developed as... more Background and purpose: Stroke is a leading cause of mortality and morbidity in both developed as well as developing countries. The clinical presentation of stroke depending on the site and extent of lesions. For the management purpose it is important to know whether we are dealing with a bleed or an infarct. Methodology: Computed Tomography (CT scan) is available most of the tertiary level hospitals in Bangladesh. This study was carried out to compare clinical diagnosis of stroke with Computed tomography (CT) scan findings in ascertaining the type of stroke (hemorrhagic or ischemic). Materials and methods: This cross-sectional comparative study was conducted in the Department of Neurology, Rajshahi Medical College Hospital during the period of January 2010 to December 2010. Total 200 stroke patients were selected by purposive sampling technique on the basis of inclusion and exclusion criteria as the study sample. . CT brain scan was done for all the patients. The clinical diagnosis...
Epilepsy is a neurological problem which is a cause of sufferings for the common people because o... more Epilepsy is a neurological problem which is a cause of sufferings for the common people because of lack of proper scientific knowledge. The incidence of epilepsy is about 0.3 to 0.5% while the prevalence is about 5 to 10 people per 1000. Newer concepts about aetiopathogenesis, classification and treatment modalities are described in brief in this review article. DOI: http://dx.doi.org/10.3329/taj.v14i2.8398 TAJ 2001; 14(2): 99-103
Peripheral neuropathy is common in chronic renal failure patients and its early detection and tr... more Peripheral neuropathy is common in chronic renal failure patients and its early detection and treatment reduces the sufferings of these patients. Studies of neuropathy in ESKD have demonstrated prevalence rates which vary from 60 to 100%. The striking pathologic features of peripheral neuropathy in patients of CRF are axonal degeneration in the most distal nerve trunks with secondary segmental demyelination. The most frequent clinical features are those of large-fiber involvement, with paresthesias, reduction in deep tendon reflexes, impaired vibration sense, weakness and muscle wasting. Patients of CRF may present with mononeuropathies or autonomic failure also. The exact cause of nerve involvement has not been identified but the middle molecule hypothesis is widely accepted. Dialysis in any form fails to improve the neuropathy but renal transplantation does improve the neurological complications. This review details the various features of neuropathy in patients of chronic renal ...
Parkinson's disease is a disease of motor manifestations but non-motor symptoms are also com... more Parkinson's disease is a disease of motor manifestations but non-motor symptoms are also common in Parkinson's disease. Little emphasis is put on non-motor symptoms of PD and there is little data on the relationship of non-motor symptoms to different aspects of the patient and the ...
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