The NIH HPC group plans, manages and supports high-performance computing systems specifically for use by the intramural NIH community. These systems include Biowulf, a 105,000+ processor Linux cluster; Helix, an interactive system for file transfer and management, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

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Biowulf Utilization
Monday, August 12th, 2024
utilization graph
Last 24 hrs
71,815 jobs submitted
57,752 jobs completed
2,570,539 CPU hrs used
19 NIH Institutes
178 Principal Investigators
295 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi
Barbosa, RC; Godoy, RSM; Ferreira, PG et al.
Open Biol , DOI://10.1098/rsob.230437 (2024)


thumbnail image from paper Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging
Occean, JR; Yang, N; Sun, Y et al.
Nat Commun , DOI://10.1038/s41467-024-50725-y (2024)


thumbnail image from paper Specialized replication of heterochromatin domains ensures self-templated chromatin assembly and epigenetic inheritance
Nathanailidou, P; Dhakshnamoorthy, J; Xiao, H et al.
Proc Natl Acad Sci U S A , DOI://10.1073/pnas.2315596121 (2024)


thumbnail image from paper Deafness DFNB128 Associated with a Recessive Variant of Human MAP3K1 Recapitulates Hearing Loss of Map3k1-Deficient Mice
Faridi, R; Yousaf, R; Inagaki, S et al.
Genes (Basel) , DOI://10.3390/genes15070845 (2024)


thumbnail image from paper The tumor microenvironment state associates with response to HPV therapeutic vaccination in patients with respiratory papillomatosis
Norberg, SM; Bai, K; Sievers, C et al.
Sci Transl Med , DOI://10.1126/scitranslmed.adj0740 (2023)


thumbnail image from paper Genetic distance and ancestry proportion modify the association between maternal genetic risk score of type 2 diabetes and fetal growth
Habtewold, TD; Wijesiriwardhana, P; Biedrzycki, RJ; Tekola-Ayele, F; ,
Hum Genomics , DOI://10.1186/s40246-024-00645-1 (2024)


thumbnail image from paper Weakly-Supervised Detection of Bone Lesions in CT
Sheng, T; Mathai, TS; Shieh, A; Summers, RM; ,
Proc SPIE Int Soc Opt Eng , DOI://10.1117/12.3008823 (2024)


thumbnail image from paper The landscape of rare genetic variants in familial Waldenström macroglobulinemia
Pemov, A; Kim, J; Luo, W et al.
Blood Neoplasia , DOI://10.1016/j.bneo.2024.100013 (2024)