Reaction: Donepezil to 1 product
- Reaction
- Reaction type
- hydroxylation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Tiseo PJ, Foley K, Friedhoff LT: An evaluation of the pharmacokinetics of donepezil HCl in patients with moderately to severely impaired renal function. Br J Clin Pharmacol. 1998 Nov;46 Suppl 1:56-60. doi: 10.1046/j.1365-2125.1998.0460s1056.x. [Article]
- Cacabelos R: Donepezil in Alzheimer's disease: From conventional trials to pharmacogenetics. Neuropsychiatr Dis Treat. 2007 Jun;3(3):303-33. [Article]
- Comments
- Not Available
- Enzymes
- Not Available