Corynebacterium diphtheriae
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Brand Names
- Prevnar 13
- Generic Name
- Corynebacterium diphtheriae
- DrugBank Accession Number
- DB09877
- Background
Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
- Type
- Biotech
- Groups
- Approved, Investigational
- Biologic Classification
- Vaccines
Other vaccines - Synonyms
- Not Available
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to prevent Diphtheria Combination Product in combination with: Clostridium tetani (DB09876) •••••••••••• •••••••••• •••••••••• Prevention of Diphtheria •••••••••••• Used in combination for prophylaxis of Tetanus Combination Product in combination with: Clostridium tetani (DB09876) •••••••••••• ••••••••• •••••••• •••••••••• •••••••••• Used in combination to prevent Tetanus Combination Product in combination with: Clostridium tetani (DB09876) •••••••••••• •••••••••• •••••••••• Prevention of Tetanus •••••••••••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Boostrix Injektionssuspension in einer Fertigspritze Corynebacterium diphtheriae (2 IU) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 μg) + Bordetella pertussis pertactin antigen (2.5 μg) + Clostridium tetani (20 IU) + Pertussis vaccine (8 μg) Injection, suspension Intramuscular GLAXOSMİTHKLİNE İLAÇLARI SAN. VE TİC. A.Ş. 2001-02-16 Not applicable Austria Boostrix Polio - Injektionssuspension in einer Fertigspritze Corynebacterium diphtheriae (2 IU/0.5ml) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 mcg/0.5ml) + Bordetella pertussis pertactin antigen (2.5 mcg/0.5ml) + Clostridium tetani (20 IU/0.5ml) + Pertussis vaccine (8 mcg/0.5ml) + Poliovirus type 1 antigen (formaldehyde inactivated) (40 [D'ag'U]/0.5ml) + Poliovirus type 2 antigen (formaldehyde inactivated) (8 [D'ag'U]/0.5ml) + Poliovirus type 3 antigen (formaldehyde inactivated) (32 [D'ag'U]/0.5ml) Injection, solution Intramuscular GLAXOSMİTHKLİNE İLAÇLARI SAN. VE TİC. A.Ş. 2004-11-05 Not applicable Austria Infanrix-IPV+Hib Pulver und Suspension zur Herstellung einer Injektionssuspension Corynebacterium diphtheriae (30 IU/0.5ml) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (25 mcg/0.5ml) + Bordetella pertussis pertactin antigen (8 mcg/0.5ml) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (40 IU/0.5ml) + Haemophilus influenzae b polysaccharide-tetanus conjugate (10 mcg/0.5ml) + Pertussis vaccine (25 mcg/0.5ml) + Poliovirus type 1 antigen (formaldehyde inactivated) (40 [D'ag'U]/0.5ml) + Poliovirus type 2 antigen (formaldehyde inactivated) (8 [D'ag'U]/0.5ml) + Poliovirus type 3 antigen (formaldehyde inactivated) (32 [D'ag'U]/0.5ml) Injection, powder, for suspension Intramuscular GLAXOSMİTHKLİNE İLAÇLARI SAN. VE TİC. A.Ş. 2010-06-04 Not applicable Austria MENJUGATE Corynebacterium diphtheriae (18.75 mcg/0.5mL) + Meningococcal polysaccharide vaccine group C (10 mcg/0.5mL) Injection, suspension Intramuscular Glaxosmithkline Vaccines S.R.L. 2015-07-16 Not applicable Italy MENJUGATE Corynebacterium diphtheriae (18.75 mcg/0.5mL) + Meningococcal polysaccharide vaccine group C (10 mcg/0.5mL) Injection, suspension Intramuscular Glaxosmithkline Vaccines S.R.L. 2015-07-16 Not applicable Italy
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 3U7E3O07S8
- CAS number
- Not Available
References
- General References
- Not Available
- External Links
- PubChem Substance
- 347910466
- Wikipedia
- Corynebacterium_diphtheriae
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Not Available Inflammatory Bowel Diseases (IBD) 1 somestatus stop reason just information to hide Not Available Unknown Status Not Available Pneumococcal Vaccine Adverse Reaction 1 somestatus stop reason just information to hide 4 Active Not Recruiting Prevention Invasive Pneumococcal Disease, Protection Against / Pneumococcal Infection / Streptococcus Pneumoniae Infections 1 somestatus stop reason just information to hide 4 Completed Basic Science Aging / Pneumonia 1 somestatus stop reason just information to hide 4 Completed Diagnostic Immune Responses / Pneumonia / Streptococcus Pneumoniae 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Intramuscular Injection, powder, for suspension Intramuscular Injection, suspension Intramuscular Suspension Intramuscular Injection Intramuscular - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at November 30, 2015 21:23 / Updated at June 12, 2020 16:52