8000 Invalid BCF, the INFO tag id=120 is too large at 1:13372 · Issue #1532 · samtools/bcftools · GitHub
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Invalid BCF, the INFO tag id=120 is too large at 1:13372 #1532

@holtgrewe

Description

@holtgrewe

Hi, I'm getting a weird problem with bcftools norm - bcftools view handles the file fine.

# bcftools norm --multiallelics - --fasta-ref GRCh37/reference/hs37d5/hs37d5.fa -O z -o out.vcf.gz exac.r1.head.vcf.gz
[W::vcf_parse_info] INFO 'HOM_CONSANGUINEOUS' is not defined in the header, assuming Type=String
[W::vcf_parse_filter] FILTER 'AC_Adj0_Filter' is not defined in the header
[E::vcf_format] Invalid BCF, the INFO tag id=120 is too large at 1:13372
[flush_buffer] Error: cannot write to out.vcf.gz

I'm using version bcftools 1.13 from bioconda, if that information is helpful. I'm attaching the exac.r1.head.vcf.gz file.

What could be the reason?

# bcftools --version
bcftools 1.13
Using htslib 1.13
Copyright (C) 2021 Genome Research Ltd.
License GPLv3+: GNU GPL version 3 or later <http://gnu.org/licenses/gpl.html>
This is free software: you are free to change and redistribute it.
There is NO WARRANTY, to the extent permitted by law.

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