diff --git a/cmake/Dependencies.cmake b/cmake/Dependencies.cmake
index 1dc33efec7b878..7a878b9e1f27f4 100644
--- a/cmake/Dependencies.cmake
+++ b/cmake/Dependencies.cmake
@@ -908,6 +908,12 @@ if(USE_SYSTEM_PYBIND11)
   if(NOT pybind11_FOUND)
     message(FATAL "Cannot find system pybind11")
   endif()
+  if(${pybind11_VERSION} VERSION_LESS 2.12)  # for pybind11::gil_safe_call_once_and_store
+    message(FATAL_ERROR
+      "Found pybind11 version ${pybind11_VERSION} which misses some features required by PyTorch. "
+      "Please install pybind11 >= 2.12.0."
+    )
+  endif()
 else()
     message(STATUS "Using third_party/pybind11.")
     set(pybind11_INCLUDE_DIRS ${CMAKE_CURRENT_LIST_DIR}/../third_party/pybind11/include)
diff --git a/functorch/csrc/dim/dim.cpp b/functorch/csrc/dim/dim.cpp
index 722618efbb090b..64e39e09d84d38 100644
--- a/functorch/csrc/dim/dim.cpp
+++ b/functorch/csrc/dim/dim.cpp
@@ -740,6 +740,8 @@ struct Tensor : public mpy::base<Tensor> {
     static mpy::obj<Tensor> create() {
         if (!TensorType) {
             TensorType = (PyTypeObject*) mpy::import("functorch.dim").attr("Tensor").ptr();
+            // NB: leak
+            Py_INCREF(TensorType);
         }
         return Tensor::alloc(TensorType);
     }
diff --git a/torch/csrc/dynamo/guards.cpp b/torch/csrc/dynamo/guards.cpp
index 0c2cf51a2cbbbb..097f1f03d3a7e5 100644
--- a/torch/csrc/dynamo/guards.cpp
+++ b/torch/csrc/dynamo/guards.cpp
@@ -26,6 +26,7 @@
 #endif
 
 #include <sstream>
+#include <tuple>
 #include <utility>
 
 // For TupleIteratorGetItemAccessor, we need a fast way to retrieve the
@@ -2461,14 +2462,24 @@ std::unique_ptr<GuardManager> make_guard_manager(
     std::string source,
     py::handle example_value,
     py::handle guard_manager_enum) {
-  static py::object guard_manager_enum_class =
-      py::module_::import("torch._dynamo.guards").attr("GuardManagerType");
-  static py::object base_guard_manager_enum =
-      guard_manager_enum_class.attr("GUARD_MANAGER");
-  static py::object dict_guard_manager_enum =
-      guard_manager_enum_class.attr("DICT_GUARD_MANAGER");
-  static py::object dict_subclass_guard_manager_enum =
-      guard_manager_enum_class.attr("DICT_SUBCLASS_GUARD_MANAGER");
+  using fourobjects =
+      std::tuple<py::object, py::object, py::object, py::object>;
+  PYBIND11_CONSTINIT static py::gil_safe_call_once_and_store<fourobjects>
+      storage;
+
+  auto& [guard_manager_enum_class, base_guard_manager_enum, dict_guard_manager_enum, dict_subclass_guard_manager_enum] =
+      storage
+          .call_once_and_store_result([]() -> fourobjects {
+            py::object guard_manager_enum_class =
+                py::module_::import("torch._dynamo.guards")
+                    .attr("GuardManagerType");
+            return {
+                guard_manager_enum_class,
+                guard_manager_enum_class.attr("GUARD_MANAGER"),
+                guard_manager_enum_class.attr("DICT_GUARD_MANAGER"),
+                guard_manager_enum_class.attr("DICT_SUBCLASS_GUARD_MANAGER")};
+          })
+          .get_stored();
   if (py::isinstance<py::dict>(example_value)) {
     // The purpose of having both DictGuardManager and DictSubclassGuardManager
     // is to handle the variability in how dictionaries and their subclasses
diff --git a/torch/csrc/jit/python/module_python.h b/torch/csrc/jit/python/module_python.h
index b1ddf6f37c6786..2be4a27293d07a 100644
--- a/torch/csrc/jit/python/module_python.h
+++ b/torch/csrc/jit/python/module_python.h
@@ -3,14 +3,21 @@
 #include <pybind11/stl.h>
 #include <torch/csrc/jit/api/module.h>
 #include <torch/csrc/utils/pybind.h>
+#include <tuple>
 
 namespace py = pybind11;
 
 namespace torch::jit {
 
 inline std::optional<Module> as_module(py::handle obj) {
-  static py::handle ScriptModule =
-      py::module::import("torch.jit").attr("ScriptModule");
+  PYBIND11_CONSTINIT static py::gil_safe_call_once_and_store<py::object>
+      storage;
+  auto& ScriptModule =
+      storage
+          .call_once_and_store_result([]() -> py::object {
+            return py::module_::import("torch.jit").attr("ScriptModule");
+          })
+          .get_stored();
   if (py::isinstance(obj, ScriptModule)) {
     return py::cast<Module>(obj.attr("_c"));
   }
@@ -18,14 +25,22 @@ inline std::optional<Module> as_module(py::handle obj) {
 }
 
 inline std::optional<Object> as_object(py::handle obj) {
-  static py::handle ScriptObject =
-      py::module::import("torch").attr("ScriptObject");
+  PYBIND11_CONSTINIT static py::gil_safe_call_once_and_store<
+      std::tuple<py::object, py::object>>
+      storage;
+  auto& [ScriptObject, RecursiveScriptClass] =
+      storage
+          .call_once_and_store_result(
+              []() -> std::tuple<py::object, py::object> {
+                return {
+                    py::module_::import("torch").attr("ScriptObject"),
+                    py::module_::import("torch.jit")
+                        .attr("RecursiveScriptClass")};
+              })
+          .get_stored();
   if (py::isinstance(obj, ScriptObject)) {
     return py::cast<Object>(obj);
   }
-
-  static py::handle RecursiveScriptClass =
-      py::module::import("torch.jit").attr("RecursiveScriptClass");
   if (py::isinstance(obj, RecursiveScriptClass)) {
     return py::cast<Object>(obj.attr("_c"));
   }
diff --git a/torch/csrc/jit/python/python_ivalue.h b/torch/csrc/jit/python/python_ivalue.h
index a5475bfb849960..b8ed28dba7aca7 100644
--- a/torch/csrc/jit/python/python_ivalue.h
+++ b/torch/csrc/jit/python/python_ivalue.h
@@ -49,8 +49,15 @@ struct C10_EXPORT ConcretePyObjectHolder final : PyObjectHolder {
     // when using C++. The reason is unclear.
     try {
       pybind11::gil_scoped_acquire ag;
-      static py::object& extractorFn = *new py::object(
-          py::module::import("torch._jit_internal").attr("_extract_tensors"));
+      PYBIND11_CONSTINIT static py::gil_safe_call_once_and_store<py::object>
+          storage;
+      auto& extractorFn =
+          storage
+              .call_once_and_store_result([]() -> py::object {
+                return py::module_::import("torch._jit_internal")
+                    .attr("_extract_tensors");
+              })
+              .get_stored();
       return extractorFn(py_obj_).cast<std::vector<at::Tensor>>();
     } catch (py::error_already_set& e) {
       auto err = std::runtime_error(
diff --git a/torch/csrc/utils/python_arg_parser.cpp b/torch/csrc/utils/python_arg_parser.cpp
index 181a66d2a13823..b52ca76830bffa 100644
--- a/torch/csrc/utils/python_arg_parser.cpp
+++ b/torch/csrc/utils/python_arg_parser.cpp
@@ -263,13 +263,15 @@ static PyObject* get_type_of_overloaded_arg(PyObject* obj_or_type) {
 static py::object maybe_get_registered_torch_dispatch_rule(
     PyObject* torch_api_function,
     const py::object& torch_dispatch_object) {
-  // This is a static object, so we must leak the Python object
-  // "release()" is used here to preserve 1 refcount on the
-  // object, preventing it from ever being de-allocated by CPython.
-  static const py::handle find_torch_dispatch_rule =
-      py::object(py::module_::import("torch._library.simple_registry")
-                     .attr("find_torch_dispatch_rule"))
-          .release();
+  PYBIND11_CONSTINIT static py::gil_safe_call_once_and_store<py::object>
+      storage;
+  py::object find_torch_dispatch_rule =
+      storage
+          .call_once_and_store_result([]() -> py::object {
+            return py::module_::import("torch._library.simple_registry")
+                .attr("find_torch_dispatch_rule");
+          })
+          .get_stored();
   auto result = find_torch_dispatch_rule(
       py::reinterpret_borrow<py::object>(torch_api_function),
       torch_dispatch_object.get_type());
diff --git a/torch/csrc/utils/python_symnode.cpp b/torch/csrc/utils/python_symnode.cpp
index f8f3d79cf3494d..d853e361139c55 100644
--- a/torch/csrc/utils/python_symnode.cpp
+++ b/torch/csrc/utils/python_symnode.cpp
@@ -3,24 +3,33 @@
 namespace torch {
 
 py::handle get_symint_class() {
-  // NB: leak
-  static py::handle symint_class =
-      py::object(py::module::import("torch").attr("SymInt")).release();
-  return symint_class;
+  PYBIND11_CONSTINIT static py::gil_safe_call_once_and_store<py::object>
+      storage;
+  return storage
+      .call_once_and_store_result([]() -> py::object {
+        return py::module::import("torch").attr("SymInt");
+      })
+      .get_stored();
 }
 
 py::handle get_symfloat_class() {
-  // NB: leak
-  static py::handle symfloat_class =
-      py::object(py::module::import("torch").attr("SymFloat")).release();
-  return symfloat_class;
+  PYBIND11_CONSTINIT static py::gil_safe_call_once_and_store<py::object>
+      storage;
+  return storage
+      .call_once_and_store_result([]() -> py::object {
+        return py::module::import("torch").attr("SymFloat");
+      })
+      .get_stored();
 }
 
 py::handle get_symbool_class() {
-  // NB: leak
-  static py::handle symbool_class =
-      py::object(py::module::import("torch").attr("SymBool")).release();
-  return symbool_class;
+  PYBIND11_CONSTINIT static py::gil_safe_call_once_and_store<py::object>
+      storage;
+  return storage
+      .call_once_and_store_result([]() -> py::object {
+        return py::module::import("torch").attr("SymBool");
+      })
+      .get_stored();
 }
 
 } // namespace torch