diff --git a/Lib/ensurepip/__init__.py b/Lib/ensurepip/__init__.py
index 97dfa7ea71f8ff..1879b55cfe2d89 100644
--- a/Lib/ensurepip/__init__.py
+++ b/Lib/ensurepip/__init__.py
@@ -11,15 +11,12 @@
 
 
 __all__ = ["version", "bootstrap"]
-
-
-_SETUPTOOLS_VERSION = "49.2.1"
-
-_PIP_VERSION = "20.2.3"
-
+_PACKAGE_NAMES = ('setuptools', 'pip')
+_SETUPTOOLS_VERSION = "52.0.0"
+_PIP_VERSION = "21.0.1"
 _PROJECTS = [
     ("setuptools", _SETUPTOOLS_VERSION, "py3"),
-    ("pip", _PIP_VERSION, "py2.py3"),
+    ("pip", _PIP_VERSION, "py3"),
 ]
 
 
diff --git a/Lib/ensurepip/_bundled/pip-20.2.3-py2.py3-none-any.whl b/Lib/ensurepip/_bundled/pip-20.2.3-py2.py3-none-any.whl
deleted file mode 100644
index 7ebdc0f31d4e3e..00000000000000
Binary files a/Lib/ensurepip/_bundled/pip-20.2.3-py2.py3-none-any.whl and /dev/null differ
diff --git a/Lib/ensurepip/_bundled/pip-21.0.1-py3-none-any.whl b/Lib/ensurepip/_bundled/pip-21.0.1-py3-none-any.whl
new file mode 100644
index 00000000000000..6d55137b941255
Binary files /dev/null and b/Lib/ensurepip/_bundled/pip-21.0.1-py3-none-any.whl differ
diff --git a/Lib/ensurepip/_bundled/setuptools-49.2.1-py3-none-any.whl b/Lib/ensurepip/_bundled/setuptools-52.0.0-py3-none-any.whl
similarity index 66%
rename from Lib/ensurepip/_bundled/setuptools-49.2.1-py3-none-any.whl
rename to Lib/ensurepip/_bundled/setuptools-52.0.0-py3-none-any.whl
index 308e2f2ed5ed9b..9eb776ecfba275 100644
Binary files a/Lib/ensurepip/_bundled/setuptools-49.2.1-py3-none-any.whl and b/Lib/ensurepip/_bundled/setuptools-52.0.0-py3-none-any.whl differ
diff --git a/Misc/NEWS.d/next/Library/2021-01-30-15-20-06.bpo-43077.Owk61z.rst b/Misc/NEWS.d/next/Library/2021-01-30-15-20-06.bpo-43077.Owk61z.rst
new file mode 100644
index 00000000000000..e555002433b4de
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2021-01-30-15-20-06.bpo-43077.Owk61z.rst
@@ -0,0 +1 @@
+Update the bundled pip to 21.0.1 and setuptools to 52.0.0.
\ No newline at end of file