About

SPARCED is a simple and efficient pipeline for constructing, merging, expanding and simulating large-scale, single-cell mechanistic models.

With minimal set-up, users can configure small-scale experiments on their local machines, is it through pure Python scripts or Jupyter Notebooks. SPARCED is also compatible with cluster running and parallelization.

The acronym SPARCED stands for SBML, Proliferation, Apoptosis, Receptor signaling, Cell cycle, Expression & DNA damage, which are sub-models of the large-scale mechanistic model.

SPARCED is a product of the Birtwistle Lab and the Erdem Lab.