DescriptionAnti-VEGF 165 and anti-IFNy aptamer secondary structure prediction.jpg
English: Illustration of the complex secondary structure of anti-VEGF_165 and anti-IFNy DNA aptamers engineered post-SELEX to improve their properties. These contain two unnatural bases (in yellow) and thymidine-conjugated biotin. Hairpin regions (red) enhance thermal stability.
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Kimoto, M., Shermane Lim, Y. W., & Hirao, I. (2019). Molecular affinity rulers: systematic evaluation of DNA aptamers for their applicabilities in ELISA. Nucleic acids research, 47(16), 8362-8374. Publisher: Oxford University Press.
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Captions
Secondary structure prediction of DNA aptamers, showing post-SELEX optimizations.
Uploaded a work by Michiko Kimoto, Yun Wei Shermane Lim, Ichiro Hirao from Kimoto, M., Shermane Lim, Y. W., & Hirao, I. (2019). Molecular affinity rulers: systematic evaluation of DNA aptamers for their applicabilities in ELISA. Nucleic acids research, 47(16), 8362-8374. Publisher: Oxford University Press. with UploadWizard
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