Probabilistic atlas based labeling of the cerebral vessel tree

20 March 2015 Probabilistic atlas based labeling of the cerebral vessel tree

Martijn Van de Giessen, Jasper P. Janssen, Patrick A. Brouwer, Johan H. C. Reiber, Boudewijn P. F. Lelieveldt, Jouke Dijkstra

Author Affiliations +

Proceedings Volume 9413, Medical Imaging 2015: Image Processing; 94130V (2015) https://doi.org/10.1117/12.2081604
Event: SPIE Medical Imaging, 2015, Orlando, Florida, United States

Abstract

Preoperative imaging of the cerebral vessel tree is essential for planning therapy on intracranial stenoses and aneurysms. Usually, a magnetic resonance angiography (MRA) or computed tomography angiography (CTA) is acquired from which the cerebral vessel tree is segmented. Accurate analysis is helped by the labeling of the cerebral vessels, but labeling is non-trivial due to anatomical topological variability and missing branches due to acquisition issues. In recent literature, labeling the cerebral vasculature around the Circle of Willis has mainly been approached as a graph-based problem. The most successful method, however, requires the definition of all possible permutations of missing vessels, which limits application to subsets of the tree and ignores spatial information about the vessel locations.

This research aims to perform labeling using probabilistic atlases that model spatial vessel and label likelihoods. A cerebral vessel tree is aligned to a probabilistic atlas and subsequently each vessel is labeled by computing the maximum label likelihood per segment from label-specific atlases.

The proposed method was validated on 25 segmented cerebral vessel trees. Labeling accuracies were close to 100% for large vessels, but dropped to 50-60% for small vessels that were only present in less than 50% of the set.

With this work we showed that using solely spatial information of the vessel labels, vessel segments from stable vessels (>50% presence) were reliably classified. This spatial information will form the basis for a future labeling strategy with a very loose topological model.

Citation Download Citation

Martijn Van de Giessen, Jasper P. Janssen, Patrick A. Brouwer, Johan H. C. Reiber, Boudewijn P. F. Lelieveldt, and Jouke Dijkstra "Probabilistic atlas based labeling of the cerebral vessel tree", Proc. SPIE 9413, Medical Imaging 2015: Image Processing, 94130V (20 March 2015); https://doi.org/10.1117/12.2081604

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available