Ocimum gratissimum L. leaf oil exhibited many pharmacological properties. This study aimed to for... more Ocimum gratissimum L. leaf oil exhibited many pharmacological properties. This study aimed to formulate and evaluate the physical and chemical stability of O.gratissimum leaf oil nanoemulsion. O.gratissimum leaf oil was extracted by hydrodistillation. The major component of the essential oil eugenol, was analyzed by UV-Vis spectrophotometry. Nanoemulsions of O.gratissimum leaf oil were formulated using polysorbate 80, hyaluronic acid, poloxamer 188, and deionized water by phase inversion composition method. The hydrodynamic diameter, polydispersity index, and zeta potential value of O.gratissimum leaf oil nanoemulsion was evaluated by a dynamic light scattering technique. The %remaining of eugenol in the nanoemulsion was analyzed by UV-Vis spectrophotometry. The essential oil extracted from of O. gratissimum leaf oil was a clear, pale yellow color. The %yield of the essential oil was 0.15 ± 0.03% v/w. The size of the nanoemulsion was less than 106 nm. The polydispersity index of the nanoemulsion was ranging from 0.303 - 0.586 and the zeta potential value of the nanoemulsion was closely to zero, depending on the formulation component. O. gratissimum leaf oil at concentrations ranging from 0.002 - 0.012% v/v contained 35 - 41% of eugenol. The size of nanoemulsion was significantly decreased after storage at 4 °C, while significantly increased upon storage at 45 °C. The size of nanoemulsion stored at 30 °C did not significantly change. The %remaining of eugenol in the nanoemulsion was more than 90% after storage at 4 °C and 30 °C for 28 days. The percentage of eugenol remaining in the nanoemulsion stored at 45 °C was more than 85 - 90%, suggesting that the temperature affected the stability of eugenol in the nanoemulsion.
Acne is the most common skin problem that could occur to any individual. Nigella sativa seed oil ... more Acne is the most common skin problem that could occur to any individual. Nigella sativa seed oil and kaolin as natural antimicrobial agents have been utilized in anti-acne cream formulated in this study. This study aimed at the development of anti-acne cream with antimicrobial properties using a crude extract of black cumin (Nigella sativa L.). Anti-acne creams had been formulated from cream-based agents with various percentages of crude black cumin seed extract and 1.0% (w/w) of mineral clay (Kaolin). Physical properties and stability of anti-acne cream at various storage conditions, including incubation at and freeze-thaw at 4, 40, and 45°C for 28 days. The results showed that developed anti-acne cream containing a crude black cumin seed extract in 0.1 and 1.5% (w/w) had good physical stability. Therefore, the suitable formulation was then tested for anti-Propionibacterium acnes (P. acnes) susceptibility by the broth dilution method. From these results, it was found that 1.0 % (w/w) of crude black cumin seed extract had the ability to inhibit P.acnes with MIC (minimal inhibition concentration) of 15.6 mg/mL.
A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat mil... more A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat milk as main ingredients, purple sweet potato, perilla seed oil, butter, egg yolk, corn starch as well as monk fruit syrup. The aims of this research were to develop a heathy custard product, characterize the fatty acid profiles, anti-scavenging activity and sensory attribute of developed purple sweet potato-based custard fortified with perilla seed oil. The fatty acid profiles of the custard containing 3 % of perilla seed oil provides the highest amount of LA (17.32 %) and ALA (25.88 %). The custard formulation containing 1% of perilla seed oil provides the highest scores in all sensory attribute terms compared to other formulations containing perilla seed oil. The purple sweet potato-based custard containing perilla seed oil provides good antioxidant activities with percent inhibition by DPPH range from 29.8 to 35.1. The result indicates the concentration-dependent of perilla seed oil in the product. The custard developed in this study provides not only an excellent source of polyunsaturated fatty acids but also an excellent source of antioxidant agent.
proceeding on the international halal science and technology conference , 2022
A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat mil... more A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat milk as main ingredients, purple sweet potato, perilla seed oil, butter, egg yolk, corn starch as well as monk fruit syrup. The aims of this research were to develop a heathy custard product, characterize the fatty acid profiles, anti-scavenging activity and sensory attribute of developed purple sweet potato-based custard fortified with perilla seed oil. The fatty acid profiles of the custard containing 3 % of perilla seed oil provides the highest amount of LA (17.32 %) and ALA (25.88 %). The custard formulation containing 1% of perilla seed oil provides the highest scores in all sensory attribute terms compared to other formulations containing perilla seed oil. The purple sweet potato-based custard containing perilla seed oil provides good antioxidant activities with percent inhibition by DPPH range from 29.8 to 35.1. The result indicates the concentration-dependent of perilla seed oil in the product. The custard developed in this study provides not only an excellent source of polyunsaturated fatty acids but also an excellent source of antioxidant agent.
A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat mil... more A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat milk as main ingredients, purple sweet potato, perilla seed oil, butter, egg yolk, corn starch as well as monk fruit syrup. The aims of this research were to develop a heathy custard product, characterize the fatty acid profiles, anti-scavenging activity and sensory attribute of developed purple sweet potato-based custard fortified with perilla seed oil. The fatty acid profiles of the custard containing 3 % of perilla seed oil provides the highest amount of LA (17.32 %) and ALA (25.88 %). The custard formulation containing 1% of perilla seed oil provides the highest scores in all sensory attribute terms compared to other formulations containing perilla seed oil. The purple sweet potato-based custard containing perilla seed oil provides good antioxidant activities with percent inhibition by DPPH range from 29.8 to 35.1. The result indicates the concentration-dependent of perilla seed oil in the product. The custard developed in this study provides not only an excellent source of polyunsaturated fatty acids but also an excellent source of antioxidant agent.
Proceedings of The International Halal Science and Technology Conference
A creamy dairy custard was developed in this study. This custard matrixs consists of low-fat milk... more A creamy dairy custard was developed in this study. This custard matrixs consists of low-fat milk as main ingredients, purple sweet potato, perilla seed oil, butter, egg yolk, corn starch as well as monk fruit syrup. The aims of this research were to develop a heathy custard product, characterize the fatty acid profiles, anti-scavenging activity and sensory attribute of developed purple sweet potato-based custard fortified with perilla seed oil. The fatty acid profiles of the custard containing 3 % of perilla seed oil provides the highest amount of LA (17.32 %) and ALA (25.88 %). The custard formulation containing 1% of perilla seed oil provides the highest scores in all sensory attribute terms compare to other formulations containing perilla seed oil. The purple sweet potato-based custard containing perilla seed oil provides good antioxidant activities with percent inhibition by DPPH range from 29.8 to 35.1. The result indicates the concentration-dependent of perilla seed oil in th...
Ocimum gratissimum L. leaf oil exhibited many pharmacological properties. This study aimed to for... more Ocimum gratissimum L. leaf oil exhibited many pharmacological properties. This study aimed to formulate and evaluate the physical and chemical stability of O.gratissimum leaf oil nanoemulsion. O.gratissimum leaf oil was extracted by hydrodistillation. The major component of the essential oil eugenol, was analyzed by UV-Vis spectrophotometry. Nanoemulsions of O.gratissimum leaf oil were formulated using polysorbate 80, hyaluronic acid, poloxamer 188, and deionized water by phase inversion composition method. The hydrodynamic diameter, polydispersity index, and zeta potential value of O.gratissimum leaf oil nanoemulsion was evaluated by a dynamic light scattering technique. The %remaining of eugenol in the nanoemulsion was analyzed by UV-Vis spectrophotometry. The essential oil extracted from of O. gratissimum leaf oil was a clear, pale yellow color. The %yield of the essential oil was 0.15 ± 0.03% v/w. The size of the nanoemulsion was less than 106 nm. The polydispersity index of the...
Ocimum gratissimum L. leaf oil exhibited many pharmacological properties. This study aimed to for... more Ocimum gratissimum L. leaf oil exhibited many pharmacological properties. This study aimed to formulate and evaluate the physical and chemical stability of O.gratissimum leaf oil nanoemulsion. O.gratissimum leaf oil was extracted by hydrodistillation. The major component of the essential oil eugenol, was analyzed by UV-Vis spectrophotometry. Nanoemulsions of O.gratissimum leaf oil were formulated using polysorbate 80, hyaluronic acid, poloxamer 188, and deionized water by phase inversion composition method. The hydrodynamic diameter, polydispersity index, and zeta potential value of O.gratissimum leaf oil nanoemulsion was evaluated by a dynamic light scattering technique. The %remaining of eugenol in the nanoemulsion was analyzed by UV-Vis spectrophotometry. The essential oil extracted from of O. gratissimum leaf oil was a clear, pale yellow color. The %yield of the essential oil was 0.15 ± 0.03% v/w. The size of the nanoemulsion was less than 106 nm. The polydispersity index of the nanoemulsion was ranging from 0.303 - 0.586 and the zeta potential value of the nanoemulsion was closely to zero, depending on the formulation component. O. gratissimum leaf oil at concentrations ranging from 0.002 - 0.012% v/v contained 35 - 41% of eugenol. The size of nanoemulsion was significantly decreased after storage at 4 °C, while significantly increased upon storage at 45 °C. The size of nanoemulsion stored at 30 °C did not significantly change. The %remaining of eugenol in the nanoemulsion was more than 90% after storage at 4 °C and 30 °C for 28 days. The percentage of eugenol remaining in the nanoemulsion stored at 45 °C was more than 85 - 90%, suggesting that the temperature affected the stability of eugenol in the nanoemulsion.
Acne is the most common skin problem that could occur to any individual. Nigella sativa seed oil ... more Acne is the most common skin problem that could occur to any individual. Nigella sativa seed oil and kaolin as natural antimicrobial agents have been utilized in anti-acne cream formulated in this study. This study aimed at the development of anti-acne cream with antimicrobial properties using a crude extract of black cumin (Nigella sativa L.). Anti-acne creams had been formulated from cream-based agents with various percentages of crude black cumin seed extract and 1.0% (w/w) of mineral clay (Kaolin). Physical properties and stability of anti-acne cream at various storage conditions, including incubation at and freeze-thaw at 4, 40, and 45°C for 28 days. The results showed that developed anti-acne cream containing a crude black cumin seed extract in 0.1 and 1.5% (w/w) had good physical stability. Therefore, the suitable formulation was then tested for anti-Propionibacterium acnes (P. acnes) susceptibility by the broth dilution method. From these results, it was found that 1.0 % (w/w) of crude black cumin seed extract had the ability to inhibit P.acnes with MIC (minimal inhibition concentration) of 15.6 mg/mL.
A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat mil... more A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat milk as main ingredients, purple sweet potato, perilla seed oil, butter, egg yolk, corn starch as well as monk fruit syrup. The aims of this research were to develop a heathy custard product, characterize the fatty acid profiles, anti-scavenging activity and sensory attribute of developed purple sweet potato-based custard fortified with perilla seed oil. The fatty acid profiles of the custard containing 3 % of perilla seed oil provides the highest amount of LA (17.32 %) and ALA (25.88 %). The custard formulation containing 1% of perilla seed oil provides the highest scores in all sensory attribute terms compared to other formulations containing perilla seed oil. The purple sweet potato-based custard containing perilla seed oil provides good antioxidant activities with percent inhibition by DPPH range from 29.8 to 35.1. The result indicates the concentration-dependent of perilla seed oil in the product. The custard developed in this study provides not only an excellent source of polyunsaturated fatty acids but also an excellent source of antioxidant agent.
proceeding on the international halal science and technology conference , 2022
A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat mil... more A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat milk as main ingredients, purple sweet potato, perilla seed oil, butter, egg yolk, corn starch as well as monk fruit syrup. The aims of this research were to develop a heathy custard product, characterize the fatty acid profiles, anti-scavenging activity and sensory attribute of developed purple sweet potato-based custard fortified with perilla seed oil. The fatty acid profiles of the custard containing 3 % of perilla seed oil provides the highest amount of LA (17.32 %) and ALA (25.88 %). The custard formulation containing 1% of perilla seed oil provides the highest scores in all sensory attribute terms compared to other formulations containing perilla seed oil. The purple sweet potato-based custard containing perilla seed oil provides good antioxidant activities with percent inhibition by DPPH range from 29.8 to 35.1. The result indicates the concentration-dependent of perilla seed oil in the product. The custard developed in this study provides not only an excellent source of polyunsaturated fatty acids but also an excellent source of antioxidant agent.
A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat mil... more A creamy dairy custard was developed in this study. This custard matrixes consists of low-fat milk as main ingredients, purple sweet potato, perilla seed oil, butter, egg yolk, corn starch as well as monk fruit syrup. The aims of this research were to develop a heathy custard product, characterize the fatty acid profiles, anti-scavenging activity and sensory attribute of developed purple sweet potato-based custard fortified with perilla seed oil. The fatty acid profiles of the custard containing 3 % of perilla seed oil provides the highest amount of LA (17.32 %) and ALA (25.88 %). The custard formulation containing 1% of perilla seed oil provides the highest scores in all sensory attribute terms compared to other formulations containing perilla seed oil. The purple sweet potato-based custard containing perilla seed oil provides good antioxidant activities with percent inhibition by DPPH range from 29.8 to 35.1. The result indicates the concentration-dependent of perilla seed oil in the product. The custard developed in this study provides not only an excellent source of polyunsaturated fatty acids but also an excellent source of antioxidant agent.
Proceedings of The International Halal Science and Technology Conference
A creamy dairy custard was developed in this study. This custard matrixs consists of low-fat milk... more A creamy dairy custard was developed in this study. This custard matrixs consists of low-fat milk as main ingredients, purple sweet potato, perilla seed oil, butter, egg yolk, corn starch as well as monk fruit syrup. The aims of this research were to develop a heathy custard product, characterize the fatty acid profiles, anti-scavenging activity and sensory attribute of developed purple sweet potato-based custard fortified with perilla seed oil. The fatty acid profiles of the custard containing 3 % of perilla seed oil provides the highest amount of LA (17.32 %) and ALA (25.88 %). The custard formulation containing 1% of perilla seed oil provides the highest scores in all sensory attribute terms compare to other formulations containing perilla seed oil. The purple sweet potato-based custard containing perilla seed oil provides good antioxidant activities with percent inhibition by DPPH range from 29.8 to 35.1. The result indicates the concentration-dependent of perilla seed oil in th...
Ocimum gratissimum L. leaf oil exhibited many pharmacological properties. This study aimed to for... more Ocimum gratissimum L. leaf oil exhibited many pharmacological properties. This study aimed to formulate and evaluate the physical and chemical stability of O.gratissimum leaf oil nanoemulsion. O.gratissimum leaf oil was extracted by hydrodistillation. The major component of the essential oil eugenol, was analyzed by UV-Vis spectrophotometry. Nanoemulsions of O.gratissimum leaf oil were formulated using polysorbate 80, hyaluronic acid, poloxamer 188, and deionized water by phase inversion composition method. The hydrodynamic diameter, polydispersity index, and zeta potential value of O.gratissimum leaf oil nanoemulsion was evaluated by a dynamic light scattering technique. The %remaining of eugenol in the nanoemulsion was analyzed by UV-Vis spectrophotometry. The essential oil extracted from of O. gratissimum leaf oil was a clear, pale yellow color. The %yield of the essential oil was 0.15 ± 0.03% v/w. The size of the nanoemulsion was less than 106 nm. The polydispersity index of the...
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