Carcinoma and Adenocarcinoma

OMICS Group Conferences invites all the participants across the globe to attend the "International Conference on Carcinoma and Adenocarcinoma” (Carcinoma-2016) slated on October 13-15,2016 at Rome, Italy.

Carcinoma-2016 directs towards addressing main issues as well as future strategies of Cancer. This is going to be the largest and most promising international conference where the program includes Clinical Oncologists, Registered Nurses, Nurse practitioners and the entire medical team involved in patient care, researchers, professional, early career individuals and patient advocates who wish to learn principles of tumor immunology and immunotherapy well as decision makers will come to discuss and debate on various aspects of the challenges, risks and investment opportunities throughout the complete information of Cancers. Conference deals with Prevention, Diagnosis,Therapy and Treatment diseases of the Organ-related Cancers and its innovative techniques. Carcinoma-2016 will also provide the three days of discussions on cancer chemotherapies are on course for staggering growth potential and may revolutionize cancer treatments over the next 10 years. The methods and improvement of Cancer and as well as to explore the new ideas and concepts on global scale and the topics include lung cancer, breast cancer, bone cancer, leukemia, blood cancer, cervical cancer, colon-rectum cancer, pediatric cancer, surgical cancer, Prostate cancer, thyroid cancer.

In Italy, the study carcinoma found that one in 10 of all cancers in men and one in 33 in women were caused by past or current alcohol intake.

3.6% of all carcinoma cases and 3.5% of cancer deaths worldwide are attributable to consumption of alcohol.

OMICS Group International is a pioneer and leading scientific event organizer, publishing around 400 Open access journals and conducting over 300 Scientific Meetings all over the globe annually with the support of more than 1000 scientific associations, 30,000 editorial board members, and 3.5 million followers to its credit.

 

Carcinoma: Cell Biology and Diagnosis

Carcinoma is a type of cancer that develops from epithelial cells Carcinomas occurs when the DNA of a cell is damaged or altered and the cell begins to grow uncontrollably and become malignant.  Genomics is the study of the sequence of these letters in your DNA. Cancer Cell biology encompasses to cancer research, in order to study the disease as a complex adaptive system.

The tumor microenvironment is the cellular environment in which the tumor exists, including surrounding blood vessels, immune cells, fibroblasts, other cells. The immune cells in the microenvironment can affect the growth and evolution of cancerous cells, such as in immune therapy. The environmental factors may produce risk in carcinoma cancer. The Physical Examination includes both objective and subjective assessments of the patient's physical being. The carcinoma cancer is diagnosed by dermascopy and skin biopsy. Dermoscopy or dermatoscopy refers to the examination of the skin using skin surface microscopy. Dermoscopy is mainly used to evaluate pigmented skin lesions. Skin biopsy is a biopsy technique in which a skin lesion is removed.

Carcinoma: Organ-specific Cancer  and Cancer Genetics

Organ specific cancer include Bladder carcinoma originate the cells lining the inside wall of the bladder. Breast cancer is an invasive tumor that develops in mammary gland. Oral cancer includes cancer of the mouth and the back of the mouth .Blood cancer hurts the blood, bone marrow, lymph, and lymphatic system. Throat cancer is a type of head and neck cancer, which includes cancer of the mouth, tonsils, nose, sinuses, salivary glands and neck lymph nodes. Cervical cancer is due to the abnormal growth of cells .Colorectal Cancer is the development of cancer in the colon or rectum .Oesophageal cancer is cancer arising from the oesophagus the food pipe that runs between the throat and the stomach. Lung cancer as carcinoma of the lung is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung. Ovarian cancer is results in abnormal cells that have the ability to invade or spread to other parts of the body. Prostate cancer is development in the male reproductive system. Cancer Genetics is rapidly improving our understanding of cancer biology, helping to identify at-risk individuals, furthering the ability to characterize malignancies, establishing treatment tailored to the molecular fingerprint of the disease, and leading to the development of new therapeutic modalities.

Carcinoma: Types

These are the various types of carcinoma:

Basal cell carcinoma, this is the most common form of all cancers. It occurs in cells lining the deepest part of the skin's outer layer.

Squamous cell carcinoma that develops on the skin is usually caused by spending too much time in the sun over the course of your life. In rare cases, it may spread to the lymph nodes.

Adenocarcinoma is neoplasia of epithelial tissue that has glandular origin, glandular characteristics or both.

Anaplastic carcinoma is a malignant neoplasm arising from the uncontrolled proliferation of transformed cells of epithelial origin. Adenosquamous carcinoma is a type of cancer that contains two types of cells squamous cells organs and gland-like cells.

Bronchogenic carcinoma is a malignant neoplasm of the lung arising from the epithelium of the bronchus or bronchiole.

Oat-cell carcinoma is a type of highly malignant cancer that most commonly arises within the lung.

Lung Carcinoma also known as pulmonary carcinoma is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.

Carcinoma: Signs and Symptoms

Bowen's disease (BD) also known as "squamous cell carcinoma " is a neoplastic skin disease; which can arise on the glans or prepuce in males and vulva in females. The malignant tumour is having a symptom as lump or bump on growth tissue made up from cancer cells which continue to multiply. Kaposi's sarcoma is a tumor caused by infection with human herpes virus 8 (HHV8) agent. Kaposi’s sarcoma (KS) is a systemic disease that can present. Merkel cell carcinoma is a rare and highly aggressive skin cancer, which, is caused by the Merkel cell polyomavirus (MCV)Sebaceous Carcinoma is an uncommon and aggressive malignant cutaneous tumour, may originate anywhere in the body where these glands are found.

Carcinoma: Treatment, Therapy and Vaccines

If cancer is only in the kidneys, which is about 60% of cases, it can be treated roughly 90% of the time with surgery. If it has spread outside of the kidneys, often into the lymph nodes, the lungs or the main vein of the kidney, then multiple therapies are used including surgery and medications. RCC is resistant to chemotherapy and radiotherapy in most cases, but does respond well to immunotherapy with interleukin-2 or interferon-alpha, biologic, or targeted therapy. In early stage cases, cryotherapy and surgery are the preferred options.

Sipuleucel-T is used to treat people with metastatic, asymptomatic, hormone-refractory prostate cancer (HRPC).Vaccine therapy is a type of treatment that uses a substance or group of substances to stimulate the immune system to destroy a tumour or infectious microorganisms such as bacteria or viruses.

Retroviral vectors have been the most preferred gene transfer systems in clinical gene therapy due to its well understood biology and its high efficiency of transduction. Oncolytic virotherapy is an emerging treatment modality which uses replication competent viruses to destroy cancers.

Carcinoma: Laboratory Diagnostic Tests

A laboratory tests is a procedure in which a sample of blood, urine, other bodily fluid, or tissue is examined to get information about a person’s health. Chromogranin-A test (Cg-A) is a 439-amino-acid protein contained in secretory granules of neuroendocrine cells, in addition to specific hormone peptides or neuropeptides.HER2 test is a member of the human epidermal growth factor receptor . Amplification plays an important role in the development and progression of certain aggressive types of cancer. Cancer genemutation test is used for the assessment of cancer risk. Tumour markers test is used for the Diagnosis, deciding on appropriate treatment, assessing response to treatment, and monitoring for cancer recurrence.

Carcinoma and Carcinogenesis

Carcinogenesis or oncogenesis or tumorigenesis is the actual formation of a cancer, whereby normal cells are transformed into cancer cells.  The process is characterized by a progression of changes at the cellular, genetic, and epigenetic level that ultimately reprogram a cell to undergo uncontrolled cell division, thereby forming a malignant mass.

Cell division is a physiological process that occurs in almost all tissues and under many circumstances. Under normal circumstances, the balance between proliferation and programmed cell death, usually in the form of apoptosis, is maintained by regulation of both processes to ensure the integrity of tissues and organs. Mutations and epimutations in DNA  lead to cancer.

Carcinoma: Advance Research

Advances in Cancer Research (ACR) have covered a remarkable period of discovery that encompasses the beginning of the revolution in biology. The first ACR volume came out in the year that Watson and Crick reported on the central dogma of biology, the DNA double helix. In the first 100 volumes are found many contributions by some of those who helped shape the revolution and who made many of the remarkable discoveries in cancer research that have developed from it. In the complex fight against cancer, Dana-Farber researchers are advancing the field on every front. They are probing the molecular changes that cause tumors, testing new drug therapies, addressing the needs of cancer survivors, and improving the delivery of care.

Carcinoma: Cancer Nanotechnology

Nano-technology, the application of  nanomedicine to cancer diagnosis and treatment, has the potential to transform clinical oncology by enhancing the efficacy of cancer chemotherapy for a wide spectrum of invasive cancers. It achieves this by enabling novel drug delivery systems which target the tumour site with several functional molecules, including tumour-specific ligands, antibodies, cytotoxic agents, and imaging probes simultaneously thereby improving tumour response rates in addition to significant reduction of the systemic toxicity associated with current chemotherapy regimens. For this reason, nanotechnology is attracting considerable scientific interest and a growing investment by the global pharmaceutical industry. Several therapeutic nano-carriers have been approved for clinical use and others are undergoing phase II and III clinical trials.

Carcinoma: Cancer Biomarkers

A cancer biomarker refers to a substance or process that is indicative of the presence of cancer in the body. A biomarker may be a molecule secreted by a tumor or a specific response of the body to the presence of cancer. Genetic, epigenetic, proteomic, glycomic, and imaging biomarkers can be used for cancer diagnosis, prognosis, and epidemiology. Ideally, such biomarkers can be assayed in non-invasively collected bio fluids like blood or serum.

While numerous challenges exist in translating biomarker research into the clinical space; a number of gene and protein based biomarkers have already been used at some point in patient care; including, AFP (Liver Cancer), BCR-ABL (Chronic Myeloid Leukaemia),BRCA1 / BRCA2 (Breast/Ovarian Cancer), BRAF V600E (Melanoma/Colorectal Cancer), CA-125 (Ovarian Cancer), CA19.9 (Pancreatic Cancer), CEA (Colorectal Cancer), EGFR (Non-small-cell lung carcinoma), HER-2 (Breast Cancer), KIT (Gastrointestinal stromal  tumor),PSA (Prostate Specific Antigen)(Prostate Cancer), S100 (Melanoma).

 

OMICS Group Conferences invites all the participants across the globe to attend the "International Conference on Carcinoma and Adenocarcinoma” (Carcinoma-2016) slated on October 13-15, 2016 at Rome, Italy.

 

         Carcinoma-2016 directs towards addressing main issues as well as future strategies of Cancer. This is going to be the largest and most promising international conference where the program includes Clinical Oncologists, Registered Nurses, Nurse practitioners and the entire medical team involved in patient care, researchers, professional, early career individuals and patient advocates who wish to learn principles of tumor immunology and immunotherapy well as decision makers will come to discuss and debate on various aspects of the challenges, risks and investment opportunities throughout the complete information of Cancers. Conference deals with Prevention, Diagnosis,Therapy and Treatment diseases of the Organ-related Cancers and its innovative techniques. Carcinoma-2016 will also provide the three days of discussions on cancer chemotherapies are on course for staggering growth potential and may revolutionize cancer treatments over the next 10 years. The methods and improvement of Cancer and as well as to explore the new ideas and concepts on global scale and the topics include lung cancer, breast cancer, bone cancer, leukemia, blood cancer, cervical cancer, colon-rectum cancer, pediatric cancer, surgical cancer, Prostate cancer, thyroid cancer.

 

In Italy, the study carcinoma found that one in 10 of all cancers in men and one in 33 in women were caused by past or current alcohol intake.

3.6% of all carcinoma cases and 3.5% of cancer deaths worldwide are attributable to consumption of alcohol.

 

OMICS Group International is a pioneer and leading scientific event organizer, publishing around 400 Open access journals and conducting over 300 Scientific Meetings all over the globe annually with the support of more than 1000 scientific associations, 30,000 editorial board members, and 3.5 million followers to its credit.