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Razvojni pluripotencijski-pridruženi protein 2 jest protein koji je kod ljudi kodiran genom DPPA2 sa hromosoma 3.[5][6][7]

DPPA2
Identifikatori
AliasiDPPA2
Vanjski ID-jeviOMIM: 614445 MGI: 2157523 HomoloGene: 79572 GeneCards: DPPA2
Lokacija gena (čovjek)
Hromosom 3 (čovjek)
Hrom.Hromosom 3 (čovjek)[1]
Hromosom 3 (čovjek)
Genomska lokacija za DPPA2
Genomska lokacija za DPPA2
Bend3q13.13Početak109,293,788 bp[1]
Kraj109,316,517 bp[1]
Lokacija gena (miš)
Hromosom 16 (miš)
Hrom.Hromosom 16 (miš)[2]
Hromosom 16 (miš)
Genomska lokacija za DPPA2
Genomska lokacija za DPPA2
Bend16|16 B5Početak48,124,271 bp[2]
Kraj48,140,086 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
chromatin binding
Ćelijska komponenta jedro
Biološki proces transcription, DNA-templated
GO:0009373 regulation of transcription, DNA-templated
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_138815

NM_028615

RefSeq (bjelančevina)

NP_620170

NP_082891

Lokacija (UCSC)Chr 3: 109.29 – 109.32 MbChr 16: 48.12 – 48.14 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 298 aminokiselina, а molekulska težina 33.784 Da.[8]

1020304050
MSDANLDSSKKNFLEGEVDDEESVILTLVPVKDDANMEQMEPSVSSTSDV
KLEKPKKYNPGHLLQTNEQFTAPQKARCKIPALPLPTILPPINKVCRDTL
RDWCQQLGLSTNGKKIEVYLRLHRHAYPEQRQDMPEMSQETRLQRCSRKR
KAVTKRARLQRSYEMNERAEETNTVEVITSAPGAMLASWARIAARAVQPK
ALNSCSIPVSVEAFLMQASGVRWCVVHGRLLSADTKGWVRLQFHAGQAWV
PTTHRRMISLFLLPACIFPSPGIEDNMLCPDCAKRNKKMMKRLMTVEK

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163530 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000072419 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Du J, Lin G, Nie ZY, Lu GX (decembar 2004). "[Molecular cloning and characterization analysis of HPESCRG1, a novel gene expressed specifically in human embryonic stem cell.]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 21 (6): 542–7. PMID 15583978.
  6. ^ "Entrez Gene: DPPA2 developmental pluripotency associated 2".
  7. ^ Klein, Rachel Herndon; Tung, Po-Yuan; Somanath, Priyanka; Fehling, Hans Joerg; Knoepfler, Paul S. (august 2018). "Genomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer". Stem Cell Research. 31: 83–94. doi:10.1016/j.scr.2018.07.009. ISSN 1876-7753. PMC 6133722. PMID 30031967.
  8. ^ "UniProt, Q7Z7J5" (jezik: engleski). Pristupljeno 7. 11. 2021.

Dopunska literatura

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