Abstract
3,5-Dihydroxy-6,7,8-trimethoxyflavone, 3-O-methylquercetin, and helichrysetin were isolated from the flowers of the Rwandese medicinal plant, Helichrysum odoratissimum. Because of inconsistencies of the mp of the latter chalcone, a synthesis of helichrysetin was developed. 3-O-Methylquercetin was shown to be an active principle as it displayed antimicrobial activity.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Infective Agents / chemical synthesis
-
Anti-Infective Agents / isolation & purification*
-
Anti-Infective Agents / pharmacology
-
Chalcone / analogs & derivatives
-
Chalcone / biosynthesis*
-
Chalcone / chemical synthesis
-
Chalcone / isolation & purification*
-
Flavonoids / isolation & purification*
-
Microbial Sensitivity Tests
-
Plants, Medicinal / analysis*
-
Propiophenones / biosynthesis*
-
Propiophenones / isolation & purification*
Substances
-
Anti-Infective Agents
-
Flavonoids
-
Propiophenones
-
Chalcone
-
helichrysetin