Bioactive glass reinforced elastomer composites for skeletal regeneration: A review

Mater Sci Eng C Mater Biol Appl. 2015 Aug:53:175-88. doi: 10.1016/j.msec.2015.04.035. Epub 2015 Apr 22.

Authors

Ehsan Zeimaran¹, Sara Pourshahrestani¹, Ivan Djordjevic², Belinda Pingguan-Murphy¹, Nahrizul Adib Kadri¹, Mark R Towler³

Affiliations

¹ Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia.
² Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia. Electronic address: ivan.djordjevic@um.edu.my.
³ Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia; Department of Mechanical & Industrial Engineering, Ryerson University, Toronto M5B 2K3, ON, Canada.

PMID: 26042705
DOI: 10.1016/j.msec.2015.04.035

Abstract

Biodegradable elastomers have clinical applicability due to their biocompatibility, tunable degradation and elasticity. The addition of bioactive glasses to these elastomers can impart mechanical properties sufficient for hard tissue replacement. Hence, a composite with a biodegradable polymer matrix and a bioglass filler can offer a method of augmenting existing tissue. This article reviews the applications of such composites for skeletal augmentation.

Keywords: Bioactive glass; Bioactivity; Bone tissue engineering; Composites; Elastomers; Scaffolds.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biocompatible Materials*
Bone Regeneration*
Elastomers*
Glass*
Tissue Engineering*
Tissue Scaffolds

Substances

Biocompatible Materials
Elastomers