CCP4 Download

Here you can download the previous version of the CCP4 Software Suite, version 8.0, code name Addingham (the latest version is here). See the announcement for further information. See also the installation instructions for details on installing CCP4. This version of the CCP4 suite is no longer supported.

Binary downloads for Apple macOS

On the Mac, CCP4 Software Suite may be conveniently configured, downloaded and automatically installed with Package Manager (recommended)

ATTENTION:
• Supported platforms: macOS 10.13 (High Sierra) and above.
• You need XQuartz installed on your Mac to run CCP4.
• Do not forget to restart your Mac each time you install XQatrz.
• iMosflm on macOS 11 (Big Sur) and 12 (Monterey) requires exactly XQartz-2.8.0.
• COOT on macOS 10.14 (Mojave) only works with XQartz-2.8.0. This possibly applies to some other old macOS versions.
• Screen Time (macOS Catalina or newer) was found to block installation and updates of CCP4 in a non-obvious way. Therefore, we recommend switching it off during the CCP4 installation and updates.
• COOT and Update Manager on macOS 11 (Big Sur) should work with XQartz-2.8.3. If COOT still crashes, try XQartz-2.8.0. This may result in a combined installation reporting version 2.8.3, but that is OK. Do not forget to restart your Mac each time you install XQatrz.
• COOT on macOS 13.0, 13.2 and possibly some other 13.XX (Ventura) hides all its windows when the delete dialogue is auto-closed. Use "keep delete active" checked or, better, upgrade or downgrade macOS. We know no better recipe.

Package Manager

Download size: 6 MB
Date: 26/04/2022

In rare circumstances, you would have to install CCP4 from a tarball.

ATTENTION:
• Supported platforms: macOS 10.13 (High Sierra) and above.
• The installation in the standard location can be completed as follows.
(1) Download the required tar.gz file(s) from the list below.
(2) Open a Terminal window and execute the following commands.
cd /Applications
sudo tar -zxf ~/Downloads/ccp4-8.0.019-macosx64.tar.gz
sudo ./ccp4-8.0/BINARY.setup
(3) Install XQartz. (check the required version in the Package Manager section above).
(4) reboot your Mac.
• To install in a non-standard location, replace /Applications in the first command with the path you want.
• If the installation folder is inside your home folder, exclude the word sudo from the second and third commands.
• If you moved existing installation to a new location, rerun BINARY.setup
• NEVER install CCP4 inside the Downloads, Desktop or Documents folders.

	CCP4 Program Suite v8.0.019	Download size: 2489 MB Date: 11/04/2024
$CCP4 is a collection of over 200 useful programs, written by various authors, which provides tools for all stages of structure solution process, plus software libraries and accompanying data. Core packages are needed for other applications in the list. SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction.$	CCP4 Program Suite v8.0.019 including SHELX	Download size: 2531 MB Date: 11/04/2024
$CCP4 is a collection of over 200 useful programs, written by various authors, which provides tools for all stages of structure solution process, plus software libraries and accompanying data. Core packages are needed for other applications in the list. SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction. ARP/wARP is Crystallographic Macromolecular Building Software from EMBL-Hamburg.$	CCP4 Program Suite v8.0.019 including SHELX and ARP/wARP v8.0	Download size: 2792 MB Date: 11/04/2024
	ARP/wARP v8.0	Download size: 261 MB Date: 29/10/2022
	MoRDa database v52	Download size: 2454 MB Date: 18/02/2023

Click here for the MD5 checksums of all files.

if anything does not work as expected.

$SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction.$

Binary downloads for Linux

On Linux systems, CCP4 Software Suite may be conveniently configured, downloaded and automatically installed with Package Manager (recommended).

ATTENTION:
See also the known issues and how to resolve them.

Package Manager

Download size: 7 MB
Date: 26/04/2022

Alternatively, the suite may be downloaded and installed in separate parts.

	CCP4 Program Suite v8.0.019	Download size: 2510 MB Date: 11/04/2024
$CCP4 is a collection of over 200 useful programs, written by various authors, which provides tools for all stages of structure solution process, plus software libraries and accompanying data. Core packages are needed for other applications in the list. SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction.$	CCP4 Program Suite v8.0.019 including SHELX	Download size: 2579 MB Date: 11/04/2024
$CCP4 is a collection of over 200 useful programs, written by various authors, which provides tools for all stages of structure solution process, plus software libraries and accompanying data. Core packages are needed for other applications in the list. SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction. ARP/wARP is Crystallographic Macromolecular Building Software from EMBL-Hamburg.$	CCP4 Program Suite v8.0.019 including SHELX and ARP/wARP v8.0	Download size: 2840 MB Date: 11/04/2024
	ARP/wARP v8.0	Download size: 261 MB Date: 29/10/2022
	MoRDa database v52	Download size: 2454 MB Date: 18/02/2023

Click here for the MD5 checksums of all files.

if anything does not work as expected.

$SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction.$

Binary downloads for MS Windows

The binary packages for Microsoft Windows are available below. These include SHELX and WinCoot (version 0.9.8.92) as optional components. If you are planning to install SHELX, please register and confirm your agreement to conditions of use at the SHELX web site. Note that the conditions are different for academic and for-profit users.

Issues have previously been reported when using CCP4 software, while having Avast AV running on Windows systems. We therefore recommend using the default Windows Defender software as an alternative when installing or using CCP4 software.

$CCP4 is a collection of over 200 useful programs, written by various authors, which provides tools for all stages of structure solution process, plus software libraries and accompanying data. Core packages are needed for other applications in the list. SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction. COOT is the Crystallographic Object-Oriented Toolkit. An interactive graphical application for macromolecular model building, model completion and validation, particularly suitable for protein modelling using X-ray data. Coot displays maps and models and allows model manipulations such as idealization, real-space refinement, manual rotation/translation, rigid-body fitting, ligand search, solvation, mutations, rotamers, Ramachandran plots, skeletonization, non-crystallographic symmetry and more.$	CCP4 Program Suite v8.0.012 + SHELX + COOT v0.9.8.92 (exe)	Download size: 2008 MB Date: 13/06/2023
$CCP4 is a collection of over 200 useful programs, written by various authors, which provides tools for all stages of structure solution process, plus software libraries and accompanying data. Core packages are needed for other applications in the list. SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction. COOT is the Crystallographic Object-Oriented Toolkit. An interactive graphical application for macromolecular model building, model completion and validation, particularly suitable for protein modelling using X-ray data. Coot displays maps and models and allows model manipulations such as idealization, real-space refinement, manual rotation/translation, rigid-body fitting, ligand search, solvation, mutations, rotamers, Ramachandran plots, skeletonization, non-crystallographic symmetry and more.$	CCP4 Program Suite v8.0.019 + SHELX + COOT v0.9.8.92 (zip)	Download size: 3099 MB Date: 11/04/2024
	Cloud Tutorials	Download size: 2391 MB Date: 24/04/2022
	COOT v0.9.8.92	Download size: 242 MB Date: 03/10/2023

Click here for the MD5 checksums of all files.

To try the latest version of the CCP4 Suite while still keeping the previous one, unpack the installer using 7z and run ccp4i2.bat or ccp4i.bat.

if anything does not work as expected.

Windows 10 WSL-1 : Installation for CCP4 Testing

Current for 25th January 2021 – NB. this is all quite experimental at the moment!

For WSL2, the following instructions may also work. In Windows 11, you don't need to install the X11 server separately, as long as you have enabled WSLg.

See below for an update for WSL2.

Jump to downloads

Installation of WSL-1 is straightforward but will require a manual installation since it is not included with the standard Windows 10 updates. Note that Windows WSL (Windows Subsystem for Linux) is still under development and is considered in Beta by Microsoft so installation does come with caveats. Kay Dederichs has also investigated using WSL-2 with CCP4, and has managed to get CCP4 working on it. His notes on this can be found here.

I installed WSL-1 using the manual install instructions & didn’t encounter any show-stopping issues (see notes below). If you follow the instructions shown on the web page below (for manual installs) & then setup the display for graphical programs you should end up with WSL-1 in a functional state (see further on) :-

https://docs.microsoft.com/en-us/windows/wsl/install-win10

V1 of WSL was chosen, as hyper-threading capability is needed for the more recent v2. At the time of writing hyperthreading was not possible on Oracle VM. If you are using an actual Windows partition it should be fine to use WSL-2 (instructions also available on the webpage). When picking the flavour of Linux to use, I would recommend Ubuntu 18.04 LTS (if available).

Firefox is broken on the Linux Install, and the google browser installs but doesn’t work. The default WSL browser works fine though.

Also note I encountered problems when copying things to & from the Windows partition in WSL-1 (lost permission settings & was unable to chmod them back). If you stick to just working with the Linux variant of Edge & downloading to the Linux partition it all works ok.

CCP4 Installation

CCP4 Installed fine (mostly, but with certain provisos) using the standard Linux version of the CCP4 installer (choose the GNU/Linux tab above). Some additional work is needed though. :-

To get aimless working, install the following from a WSL terminal,

sudo apt-get install libgomp1

All the other command-line programs I tried worked (this doesn’t cover every single binary though).

The installer may run slower than it usually does, but it does work – please don’t interrupt it if it’s taking a few minutes longer than usual.

*IMPORTANT* For graphical programs, you will need to setup the display & x11 correctly :-

echo "export DISPLAY=localhost:0.0" >> ~/.bashrc

source ~/.bashrc

and you will also need to setup x11 for graphical stuff (& have it running).

install VcXsrv

https://sourceforge.net/projects/vcxsrv/

In order to get coot running (I suspect libglu is the one that matters, but it doesn’t harm to have all of them) install,

sudo apt-get install guile-2.2-libs

sudo apt-get install guile-2.2-dev

sudo apt-get install libglu1-mesa

To run jligand (still doesn't work fully though)

sudo apt-get install default-jre

Google Chrome doesn't work in WSL-1 but for information purposes this is how to get it anyway :-

wget https://dl.google.com/linux/direct/google-chrome-stable_current_amd64.deb

sudo apt-get install ./google-chrome-stable_current_amd64.deb

google-chrome

google-chrome-stable

To get CCP4Cloud running (wslview is the default WSL browser – the first command is just to test it’s working ok!) :-

wslview https://www.bbc.co.uk

ccp4cloud-config.sh -b wslview

ccp4cloud-config.sh

ccp4cloud-desktop.sh

If you try this, & wish to ask anything, you can e-mail us at :- ccp4@stfc.ac.uk

On WSL2, add the following lines to the .wslconfig file (under the %userprofile% directory in Windows; for example: C:\Users\yourname\):

[wsl2] kernelCommandLine = vsyscall=emulate

and restart WSL (type wsl --shutdown in Powershell). This change is required to run the statically linked binaries in the SHELX suite and ARP/wARP. This solution was found by Kay Diederichs.

Update April 2024:

The CCP4 Suite for Linux installs and runs on Ubuntu 20.04 and 22.04 under WSL2 on Windows 11, with WSLg enabled.

On Ubuntu 20.04, make sure the following packages are installed:

apt install tcsh libxi6 libxrandr2 libglib2.0-0 libxinerama1 binutils libxss1 libgomp1 libopengl0 libglu1-mesa libxdamage1 libxkbcommon0 libxcb-icccm4 libxcb-xkb1 libxkbcommon-x11-0 libxcb-render-util0 libxcb-image0 libxcb-keysyms1 libxcb-xinerama0 libxcb-xinput0 libxcb-xfixes0

On Ubuntu 22.04, install these additional packages:

sudo apt install libncurses5 libtinfo5 libxcb-xinerama0 libxcb-xinput0

If it still doesn't run, or you are using a different distribution in WSL, refer to the known issues document. In particular, it may help to run the find-missing-libs.sh script.

Windows 10 WSL: Downloads

CCP4 Software Suite may be conveniently configured, downloaded and automatically installed with Package Manager (recommended).

Package Manager

Download size: 7 MB
Date: 26/04/2022

Alternatively, the suite may be downloaded and installed in separate parts. ARP/wARP requires a separate licence from EMBL-Hamburg, so you will first be redirected to their website.

	CCP4 Program Suite v8.0.019	Download size: 2510 MB Date: 11/04/2024
$CCP4 is a collection of over 200 useful programs, written by various authors, which provides tools for all stages of structure solution process, plus software libraries and accompanying data. Core packages are needed for other applications in the list. SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction.$	CCP4 Program Suite v8.0.019 including SHELX	Download size: 2579 MB Date: 11/04/2024
$CCP4 is a collection of over 200 useful programs, written by various authors, which provides tools for all stages of structure solution process, plus software libraries and accompanying data. Core packages are needed for other applications in the list. SHELX is a set of programs for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction. ARP/wARP is Crystallographic Macromolecular Building Software from EMBL-Hamburg.$	CCP4 Program Suite v8.0.019 including SHELX and ARP/wARP v8.0	Download size: 2840 MB Date: 11/04/2024
	MoRDa database v52	Download size: 2454 MB Date: 18/02/2023

CCP4 Source Packages

Once compiled, the CCP4 source package allows automatic updates directly from the CCP4 source code repositories. It includes suitable Python and Tcl/Tk software, and can build COOT and CCP4 Molecular Graphics. See the README file in the package, or read it online.

CCP4 Program Suite 8.0

Download size: 4194 MB
Date: 09/02/2023

Click here for the MD5 checksums of all files.

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CCP4 Download pages

Binary downloads for Apple macOS

Binary downloads for Linux

Binary downloads for MS Windows

Windows 10 WSL-1 : Installation for CCP4 Testing

Windows 10 WSL: Downloads

CCP4 Source Packages