There has been an exponential increase in interest in the area of in vitro enzyme-catalyzed
organic reactions, since many families of enzymes can be utilized for transformation of not …

Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last
decade, and the field has become a rapidly growing area in the pharmaceutical industry …

Since optical coherence tomography (OCT) was first performed in humans two decades ago,
this imaging modality has been widely adopted in research on coronary atherosclerosis and …

During the process of autophagy, autophagosomes undergo a maturation process
consisting of multiple fusions with endosomes and lysosomes, which provide an acidic …

The thyroid-specific enhancer-binding protein (T/ebp) gene was disrupted by homologous
recombination in embryonic stem cells to generate mice lacking T/EBP expression …

Adiponectin (Ad) is a hormone secreted by adipocytes that regulates energy homeostasis
and glucose and lipid metabolism. However, the signaling pathways that mediate the …

Adiponectin is an adipocyte-derived hormone. Recent genome-wide scans have mapped a
susceptibility locus for type 2 diabetes and metabolic syndrome to chromosome 3q27, where …

Agonist-induced activation of peroxisome proliferator-activated receptor γ (PPARγ) is known
to cause adipocyte differentiation and insulin sensitivity. The biological role of PPARγ was …

The debrisoquine-4-hydroxylase polymorphism is a genetic variation in oxidative drug
metabolism characterized by two phenotypes, the extensive metabolizer (EM) and poor …

Hepatitis C virus (HCV) is the main cause of chronic hepatitis worldwide. Chronic hepatitis
ultimately results in the development of hepatocellular carcinoma 1, 2 (HCC). However, the …