The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010,
and the second edition was published in 2015 by the Japanese Society of Gastroenterology …

Nonalcoholic fatty liver disease (NAFLD) has become a serious public health issue not only
in Western countries but also in Japan. Within the wide spectrum of NAFLD, nonalcoholic …

Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing
inflammatory diseases of the intestinal tract and generally refers to ulcerative colitis (UC) …

Hepatitis C virus (HCV) is the main cause of chronic hepatitis worldwide. Chronic hepatitis
ultimately results in the development of hepatocellular carcinoma 1, 2 (HCC). However, the …

The mechanism of hepatocarcinogenesis in hepatitis C virus (HCV) infection is still
undefined. One possibility is the involvement of oxidative stress, which can produce genetic …

Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide, which finally leads
to development of hepatocellular carcinoma. Chronic hepatitis C is characterized by several …

Background & Aims: Epidemiological studies have suggested a linkage between type 2
diabetes and chronic hepatitis C virus (HCV) infection. However, the presence of additional …

Background & Aims Obesity defined by body mass index (BMI) significantly increases the
risk of hepatocellular carcinoma (HCC). In contrast, not only obesity but also underweight is …

Hepatitis C virus (HCV), a major causative agent of non-A, non-B chronic hepatitis, is also
suggested to be associated with extrahepatic manifestations such as mixed …

We studied the development of liver tumors in male HBx gene transgenic mice. Of two
lineages studied, in the lineage with the lowest HBx gene expression liver tumors developed …