Objective To determine the most effective tocolytic agent at delaying delivery. Design
Systematic review and network meta-analysis. Data sources Cochrane Central Register of …

▪ Abstract The venoms of predatory cone snails represent a rich combinatorial-like library of
evolutionarily selected, neuropharmacologically active peptides. A major fraction of the …

▪ Abstract Spindle microtubules interact with mitotic chromosomes, binding to their
kinetochores to generate forces that are important for accurate chromosome segregation …

We have developed a computer software package, IMOD, as a tool for analyzing and
viewing three-dimensional biological image data. IMOD is useful for studying and modeling …

Background Hemophilia B, an X-linked disorder, is ideally suited for gene therapy. We
investigated the use of a new gene therapy in patients with the disorder. Methods We …

Recombinant adeno-associated virus (rAAV) vectors encoding human factor VIII (hFVIII)
were systematically evaluated for hemophilia A (HA) gene therapy. A 5.7-kb rAAV …

Background In patients with severe hemophilia B, gene therapy that is mediated by a novel
self-complementary adeno-associated virus serotype 8 (AAV8) vector has been shown to …

To paralyze their more agile prey, the venomous fish-hunting cone snails (Conus) have
developed a potent biochemical strategy. They produce several classes of toxic peptides …

In recent years the kinesin superfamily has become so large that several different naming
schemes have emerged, leading to confusion and miscommunication. Here, we set forth a …

The epidermal growth factor receptor (EGFR) and one of its ligands, transforming growth
factor α (TGF-α), are thought to function as a potential autocrine loop in non-small cell lung …